Table 4 Life years gained per 1000 individuals screened compared to no screening by risk factor cohort and screening regimen: Mean predictions are shown with 95% prediction intervals
From: Evaluating risk factor assumptions: a simulation-based approach
| Â | Age at initiation (years) | Â | |
|---|---|---|---|
| Â | 50 | 45 | Difference* |
Risk Factors: | Â | Â | Â |
None | 128 (108, 155) | 146 (122, 181) | 18 (14, 26) |
100% more adenomas | 248 (210, 298) | 281 (236, 346) | 33 (25, 48) |
30% faster adenoma growth | 236 (198, 272) | 276 (230, 322) | 41 (21, 51) |
Preclinical transition sizes as if 30% larger | 232 (198, 267) | 271 (229, 317) | 39 (31, 50) |