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Figure 4 | BMC Medical Informatics and Decision Making

Figure 4

From: Decision curve analysis revisited: overall net benefit, relationships to ROC curve analysis, and application to case-control studies

Figure 4

Application of decision curve analysis to a case-control study. Decision curves for a simple model, a complex model, the reference strategies to treat none or all, and a hypothetical perfect prediction model based on the overall net benefit for an assumed true prevalence of π 0 = 0.15 (a), π 0 = 0.45 (b) and π 0 = 0.30 (c), the latter corresponding to the empirical prevalence π. While (c) is a reasonable assumption if the data are representative of the population of interest, this may no longer be the case if the data originate from a case-control study.

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