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  1. The promises of improved health care and health research through data-intensive applications rely on a growing amount of health data. At the core of large-scale data integration efforts, clinical data warehous...

    Authors: Elena Pavlenko, Daniel Strech and Holger Langhof

    Citation: BMC Medical Informatics and Decision Making 2020 20:157

    Content type: Research article

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  2. Despite the numerous healthcare smartphone applications for self-management of diabetes, patients often fail to use these applications consistently due to various limitations, including difficulty in inputting...

    Authors: Sung Woon Park, Gyuri Kim, You-Cheol Hwang, Woo Je Lee, Hyunjin Park and Jae Hyeon Kim

    Citation: BMC Medical Informatics and Decision Making 2020 20:156

    Content type: Study protocol

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  3. Evidence-based Clinical Decision Support Systems (CDSSs) usually obtain clinical evidences from randomized controlled trials based on coarse-grained groups. Individuals who are beyond the scope of the original...

    Authors: Junyi Yang, Liang Xiao and Kangning Li

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):138

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  4. Circular RNAs (circRNAs) are those RNA molecules that lack the poly (A) tails, which present the closed-loop structure. Recent studies emphasized that some circRNAs imply different functions from canonical tra...

    Authors: Yidan Wang, Xuanping Zhang, Tao Wang, Jinchun Xing, Zhun Wu, Wei Li and Jiayin Wang

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):137

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  5. Bladder cancer (BC) is regarded as one of the most fatal cancer around the world. Nevertheless, there still lack of sufficient markers to predict the prognosis of BC patients. Herein, we aim to establish a pro...

    Authors: Xiaolong Zhang, Meng Zhang, Xuanping Zhang, Xiaoyan Zhu and Jiayin Wang

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):136

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  6. Hepatocellular carcinoma is one of the most general malignant neoplasms in adults with high mortality. Mining relative medical knowledge from rapidly growing text data and integrating it with other existing bi...

    Authors: Nan Li, Zhihao Yang, Ling Luo, Lei Wang, Yin Zhang, Hongfei Lin and Jian Wang

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):135

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  7. It is of utmost importance to investigate novel therapies for cancer, as it is a major cause of death. In recent years, immunotherapies, especially those against immune checkpoints, have been developed and bro...

    Authors: Yuyu Zheng, Xiangyu Meng, Pierre Zweigenbaum, Lingling Chen and Jingbo Xia

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):133

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  8. With China experiencing unprecedented economic development and social change over the past three decades, Chinese policy makers and health care professionals have come to view mental health as an important out...

    Authors: Wenyan Tan, Haicheng Lin, Baoxin Lei, Aihua Ou, Zehui He, Ning Yang, Fujun Jia, Heng Weng and Tianyong Hao

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):132

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  9. The interpretability of results predicted by the machine learning models is vital, especially in the critical fields like healthcare. With the increasingly adoption of electronic healthcare records (EHR) by th...

    Authors: Peipei Chen, Wei Dong, Jinliang Wang, Xudong Lu, Uzay Kaymak and Zhengxing Huang

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):131

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  10. The social Q&A community quickly becomes a popular platform for consumers to find health information because of its convenience and interactivity.

    Authors: Wang Zhao, Peixin Lu, Siwei Yu and Long Lu

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):130

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  11. With the rapid development of sequencing technologies, collecting diverse types of cancer omics data become more cost-effective. Many computational methods attempted to represent and fuse multiple omics into a...

    Authors: Kaiwen Tan, Weixian Huang, Jinlong Hu and Shoubin Dong

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):129

    Content type: Research

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    This article is part of a Supplement: Volume 20 Supplement 3

  12. Nowadays, the latent power of technology, which can offer innovative resolutions to disease diagnosis, has awakened high-level anticipation in the community of patients as well as professionals. An easy-to-use...

    Authors: Fan Guo, Weiqing Li, Xin Zhao, Junfeng Qiu and Yuxiang Mai

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):128

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  13. In the few studies of clinical experience available, cigarette smoking may be associated with ischemic heart disease and acute coronary events, which can be reflected in the electrocardiogram (ECG). However, t...

    Authors: Kuo-Kun Tseng, Jiaqian Li, Yih-Jing Tang, Ching Wen Yang and Fang-Ying Lin

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):127

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  14. Cardiogenic stroke has increasing morbidity in China and brought economic burden to patient families. In cardiogenic stroke diagnosis, echocardiograph examination is one of the most important examinations. Son...

    Authors: Lu Qin, Xiaowei Xu, Lingling Ding, Zixiao Li and Jiao Li

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):126

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  15. To provide satisfying answers, medical QA system has to understand the intentions of the users’ questions precisely. For medical intent classification, it requires high-quality datasets to train a deep-learnin...

    Authors: Nan Chen, Xiangdong Su, Tongyang Liu, Qizhi Hao and Ming Wei

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):125

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  16. Reinforcement learning (RL) provides a promising technique to solve complex sequential decision making problems in healthcare domains. Recent years have seen a great progress of applying RL in addressing decis...

    Authors: Chao Yu, Guoqi Ren and Yinzhao Dong

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):124

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  17. Electronic medical records contain a variety of valuable medical information for patients. So, when we are able to recognize and extract risk factors for disease from EMRs of patients with cardiovascular disea...

    Authors: Zhichang Zhang, Yanlong Qiu, Xiaoli Yang and Minyu Zhang

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):123

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  18. The increasing global cancer incidence corresponds to serious health impact in countries worldwide. Knowledge-powered health system in different languages would enhance clinicians’ healthcare practice, patient...

    Authors: Hetong Ma, Feihong Yang, Jiansong Ren, Ni Li, Min Dai, Xuwen Wang, An Fang, Jiao Li, Qing Qian and Jie He

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):122

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  19. Blood cultures are often performed to detect patients who has a serious illness without infections and patients with bloodstream infections. Early positive blood culture prediction is important, as bloodstream...

    Authors: Ming Cheng, Xiaolei Zhao, Xianfei Ding, Jianbo Gao, Shufeng Xiong and Yafeng Ren

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):121

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  20. Although clinical guidelines provide the best practice for medical activities, there are some limitations in using clinical guidelines to assistant decision-making in practical application, such as long update...

    Authors: Haifeng Xu, Jianfei Pang, Xi Yang, Mei Li and Dongsheng Zhao

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):120

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  21. Deep learning based on segmentation models have been gradually applied in biomedical images and achieved state-of-the-art performance for 3D biomedical segmentation. However, most of existing biomedical segmen...

    Authors: Xibin Jia, Yunfeng Liu, Zhenghan Yang and Dawei Yang

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):119

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  22. A semi-supervised model is proposed for extracting clinical terms of Traditional Chinese Medicine using feature words.

    Authors: Liangliang Liu, Xiaojing Wu, Hui Liu, Xinyu Cao, Haitao Wang, Hongwei Zhou and Qi Xie

    Citation: BMC Medical Informatics and Decision Making 2020 20(Suppl 3):118

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 20 Supplement 3

  23. Various methods based on k-anonymity have been proposed for publishing medical data while preserving privacy. However, the k-anonymity property assumes that adversaries possess fixed background knowledge. Althoug...

    Authors: Hyukki Lee and Yon Dohn Chung

    Citation: BMC Medical Informatics and Decision Making 2020 20:155

    Content type: Research article

    Published on:

  24. The increasing complexity of current drug therapies jeopardizes patient adherence. While individual needs to simplify a medication regimen vary from patient to patient, a straightforward approach to integrate ...

    Authors: Viktoria S. Wurmbach, Steffen J. Schmidt, Anette Lampert, Eduard Frick, Michael Metzner, Simone Bernard, Petra A. Thürmann, Stefan Wilm, Achim Mortsiefer, Attila Altiner, Lisa Sparenberg, Joachim Szecsenyi, Frank Peters-Klimm, Petra Kaufmann-Kolle, Walter E. Haefeli and Hanna M. Seidling

    Citation: BMC Medical Informatics and Decision Making 2020 20:154

    Content type: Research article

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  25. Electronic personal health records (ePHRs) are defined as electronic applications through which individuals can access, manage, and share health information in a private, secure, and confidential environment. ...

    Authors: Zahra Niazkhani, Esmaeel Toni, Mojgan Cheshmekaboodi, Andrew Georgiou and Habibollah Pirnejad

    Citation: BMC Medical Informatics and Decision Making 2020 20:153

    Content type: Research article

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  26. For real-time monitoring of hospital patients, high-quality inference of patients’ health status using all information available from clinical covariates and lab test results is essential to enable successful ...

    Authors: Li-Fang Cheng, Bianca Dumitrascu, Gregory Darnell, Corey Chivers, Michael Draugelis, Kai Li and Barbara E Engelhardt

    Citation: BMC Medical Informatics and Decision Making 2020 20:152

    Content type: Technical Advance

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  27. Recent studies increasingly examine social support for diabetes self-management delivered via mHealth. In contrast to previous studies examining social support as an outcome of technology use, or technology as...

    Authors: Nicola Brew-Sam, Arul Chib and Constanze Rossmann

    Citation: BMC Medical Informatics and Decision Making 2020 20:151

    Content type: Research article

    Published on:

  28. Patients with diabetes are at an increased risk of readmission and mortality when discharged from hospital. Existing research identifies statistically significant risk factors that are thought to underpin thes...

    Authors: Tim Robbins, Sarah N. Lim Choi Keung, Sailesh Sankar, Harpal Randeva and Theodoros N. Arvanitis

    Citation: BMC Medical Informatics and Decision Making 2020 20:150

    Content type: Research article

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  29. Combining MRI techniques with machine learning methodology is rapidly gaining attention as a promising method for staging of brain gliomas. This study assesses the diagnostic value of such a framework applied ...

    Authors: Carole H. Sudre, Jasmina Panovska-Griffiths, Eser Sanverdi, Sebastian Brandner, Vasileios K. Katsaros, George Stranjalis, Francesca B. Pizzini, Claudio Ghimenton, Katarina Surlan-Popovic, Jernej Avsenik, Maria Vittoria Spampinato, Mario Nigro, Arindam R. Chatterjee, Arnaud Attye, Sylvie Grand, Alexandre Krainik…

    Citation: BMC Medical Informatics and Decision Making 2020 20:149

    Content type: Research article

    Published on:

  30. Prostate cancer (PCa) represents a significant healthcare problem. The critical clinical question is the need for a biopsy. Accurate risk stratification of patients before a biopsy can allow for individualised...

    Authors: Amirhossein Jalali, Robert W. Foley, Robert M. Maweni, Keefe Murphy, Dara J. Lundon, Thomas Lynch, Richard Power, Frank O’Brien, Kieran J. O’Malley, David J. Galvin, Garrett C. Durkan, T. Brendan Murphy and R. William Watson

    Citation: BMC Medical Informatics and Decision Making 2020 20:148

    Content type: Research article

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  31. Semantic interoperability is essential for improving data quality and sharing. The ISO/IEC 11179 Metadata Registry (MDR) standard has been highlighted as a solution for standardizing and registering clinical d...

    Authors: Hye Hyeon Kim, Yu Rang Park, Suehyun Lee and Ju Han Kim

    Citation: BMC Medical Informatics and Decision Making 2020 20:147

    Content type: Technical advance

    Published on:

  32. The design and internal layout of modern operating rooms (OR) are influencing the surgical team’s collaboration and communication, ergonomics, as well as intraoperative hygiene substantially. Yet, there is no ...

    Authors: Juliane Neumann, Christine Angrick, Celina Höhn, Dirk Zajonz, Mohamed Ghanem, Andreas Roth and Thomas Neumuth

    Citation: BMC Medical Informatics and Decision Making 2020 20:145

    Content type: Research article

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  33. Clinical intuition and nonanalytic reasoning play a major role in clinical hypothesis generation; however, clinicians’ intuition about whether a critically ill child is bacteremic has not been explored. We end...

    Authors: Katherine E. M. Hoops, James C. Fackler, Anne King, Elizabeth Colantuoni, Aaron M. Milstone and Charlotte Woods-Hill

    Citation: BMC Medical Informatics and Decision Making 2020 20:144

    Content type: Research article

    Published on:

  34. As a kind of widely distributed disease in China, acquired immune deficiency syndrome (AIDS) has been quickly growing each year, become a serious problem and caused serious damage to the life and health of peo...

    Authors: Zeming Li and Yanning Li

    Citation: BMC Medical Informatics and Decision Making 2020 20:143

    Content type: Research article

    Published on:

  35. The adoption of robotic-assisted surgery (RAS) requires a clear willingness, not only from healthcare organization to operate the robotic system but also from the public that is going to perceive it. This stud...

    Authors: Ali Jasem Buabbas, Saad Aldousari and Abrar Abdulmohsen Shehab

    Citation: BMC Medical Informatics and Decision Making 2020 20:140

    Content type: Research article

    Published on:

  36. The main objective of phase I cancer clinical trials is to identify the maximum tolerated dose, usually defined as the highest dose associated with an acceptable level of severe toxicity during the first cycle...

    Authors: D. Dinart, J. Fraisse, D. Tosi, A. Mauguen, C. Touraine, S. Gourgou, M. C. Le Deley, C. Bellera and C. Mollevi

    Citation: BMC Medical Informatics and Decision Making 2020 20:134

    Content type: Software

    Published on:

  37. Cancer is a leading cause of death in the United States. Primary care providers (PCPs) juggle patient cancer prevention and screening along with managing acute and chronic health problems. However, clinical de...

    Authors: Melissa L. Harry, Daniel M. Saman, Anjali R. Truitt, Clayton I. Allen, Kayla M. Walton, Patrick J. O’Connor, Heidi L. Ekstrom, JoAnn M. Sperl-Hillen, Joseph A. Bianco and Thomas E. Elliott

    Citation: BMC Medical Informatics and Decision Making 2020 20:117

    Content type: Research article

    Published on:

  38. Learning from routine healthcare data is important for the improvement of the quality of care. Providing feedback on clinicians’ performance in comparison to their peers has been shown to be more efficient for...

    Authors: Kassaye Yitbarek Yigzaw, Andrius Budrionis, Luis Marco-Ruiz, Torje Dahle Henriksen, Peder A. Halvorsen and Johan Gustav Bellika

    Citation: BMC Medical Informatics and Decision Making 2020 20:116

    Content type: Technical advance

    Published on:

  39. There is a shortage of medical informatics and data science platforms using cloud computing on electronic medical record (EMR) data, and with computing capacity for analyzing big data. We implemented, describe...

    Authors: Louis Ehwerhemuepha, Gary Gasperino, Nathaniel Bischoff, Sharief Taraman, Anthony Chang and William Feaster

    Citation: BMC Medical Informatics and Decision Making 2020 20:115

    Content type: Research article

    Published on:

  40. Incorporating patient preference (PP) information into decision-making has become increasingly important to many stakeholders. However, there is little guidance on which patient preference assessment methods, ...

    Authors: Chiara Whichello, Bennett Levitan, Juhaeri Juhaeri, Vaishali Patadia, Rachael DiSantostefano, Cathy Anne Pinto and Esther W. de Bekker-Grob

    Citation: BMC Medical Informatics and Decision Making 2020 20:114

    Content type: Research article

    Published on:

  41. Due to the increasing complexity in socioeconomic environments and the ambiguity in human cognition, decision makers prefer to give linguistic cognitive information with different granularities according to th...

    Authors: Wei Lu, Xin-pu Wang, Jie Zhao and Yun-kai Zhai

    Citation: BMC Medical Informatics and Decision Making 2020 20:113

    Content type: Research article

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  42. Transient ischemic attack (TIA) is a brief episode of neurological dysfunction resulting from cerebral ischemia not associated with permanent cerebral infarction. TIA is associated with high diagnostic errors ...

    Authors: Alia Stanciu, Mihai Banciu, Alireza Sadighi, Kyle A. Marshall, Neil R. Holland, Vida Abedi and Ramin Zand

    Citation: BMC Medical Informatics and Decision Making 2020 20:112

    Content type: Research article

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  43. Early warning scores (EWS) have been developed as clinical prognostication tools to identify acutely deteriorating patients. In the past few years, there has been a proliferation of studies that describe the d...

    Authors: Andrew Hao Sen Fang, Wan Tin Lim and Tharmmambal Balakrishnan

    Citation: BMC Medical Informatics and Decision Making 2020 20:111

    Content type: Research article

    Published on:

  44. The essential proteins in protein networks play an important role in complex cellular functions and in protein evolution. Therefore, the identification of essential proteins in a network can help to explain th...

    Authors: Caiyan Dai, Ju He, Kongfa Hu and Youwei Ding

    Citation: BMC Medical Informatics and Decision Making 2020 20:110

    Content type: Research article

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  45. There are increasing examples of linking data on healthcare resource use and patient outcomes from different sectors of health and social care systems. Linked data are generally anonymised, meaning in most jur...

    Authors: Mary P. Tully, Cecilia Bernsten, Mhairi Aitken and Caroline Vass

    Citation: BMC Medical Informatics and Decision Making 2020 20:109

    Content type: Research article

    Published on:

  46. Predictive patient stratification is greatly emerging, because it allows us to prospectively identify which patients will benefit from what interventions before their condition worsens. In the biomedical resea...

    Authors: Thanh-Trung Giang, Thanh-Phuong Nguyen and Dang-Hung Tran

    Citation: BMC Medical Informatics and Decision Making 2020 20:108

    Content type: Research article

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  47. Health care practice relies on evidence-based decisions and needs the use of quality health care data. Health management information system (HMIS) is among the core elements of health system building blocks. I...

    Authors: Mekonen Kebede, Emiru Adeba and Melese Chego

    Citation: BMC Medical Informatics and Decision Making 2020 20:107

    Content type: Research article

    Published on:

  48. Infectious diseases that can cause epidemics, such as COVID-19, SARS-CoV, and MERS-CoV, constitute a major social issue, with healthcare providers fearing secondary, tertiary, and even quaternary infections. T...

    Authors: Dong-won Kim, Jin-young Choi and Keun-hee Han

    Citation: BMC Medical Informatics and Decision Making 2020 20:106

    Content type: Research article

    Published on:

  49. Prior studies have explored the use of regular reminders to improve adherence among kidney transplant recipients (KTRs), but none have included real-time alarms about drug dosage, frequency, and interval. In t...

    Authors: Hee-Yeon Jung, Yena Jeon, Sook Jin Seong, Jung Ju Seo, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Chan-Duck Kim, Young-Ran Yoon, Se-Hee Yoon, Jong Soo Lee and Yong-Lim Kim

    Citation: BMC Medical Informatics and Decision Making 2020 20:105

    Content type: Research article

    Published on:

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