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  1. The analysis of large-scale gene expression data is a fundamental approach to functional genomics and the identification of potential drug targets. Results derived from such studies cannot be trusted unless th...

    Authors: Peyman Jafari and Francisco Azuaje

    Citation: BMC Medical Informatics and Decision Making 2006 6:27

    Content type: Research article

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  3. The Cancer Biomedical Informatics Grid (caBIG™) is a network of individuals and institutions, creating a world wide web of cancer research. An important aspect of this informatics effort is the development of ...

    Authors: Jonathan Tobias, Ram Chilukuri, George A Komatsoulis, Sambit Mohanty, Nicholas Sioutos, Denise B Warzel, Lawrence W Wright and Rebecca S Crowley

    Citation: BMC Medical Informatics and Decision Making 2006 6:25

    Content type: Research article

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  6. Computerized decision support systems (DSS) have mainly focused on improving clinicians' diagnostic accuracy in unusual and challenging cases. However, since diagnostic omission errors may predominantly result...

    Authors: Padmanabhan Ramnarayan, Graham C Roberts, Michael Coren, Vasantha Nanduri, Amanda Tomlinson, Paul M Taylor, Jeremy C Wyatt and Joseph F Britto

    Citation: BMC Medical Informatics and Decision Making 2006 6:22

    Content type: Research article

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  7. Clinical research can be facilitated by the use of informatics tools. We used an existing electronic medical record (EMR) system and personal data assistants (PDAs) to assess the characteristics and outcomes o...

    Authors: Lameck Diero, Joseph K Rotich, John Bii, Burke W Mamlin, Robert M Einterz, Irene Z Kalamai and William M Tierney

    Citation: BMC Medical Informatics and Decision Making 2006 6:21

    Content type: Research article

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  8. PROforma is one of several languages that allow clinical guidelines to be expressed in a computer-interpretable manner. How these languages should be compared, and what requirements they should meet, are quest...

    Authors: David R Sutton, Paul Taylor and Kenneth Earle

    Citation: BMC Medical Informatics and Decision Making 2006 6:20

    Content type: Research article

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  9. The National Institute of Diabetes and Digestive and Kidney Diseases have established central repositories for the collection of DNA, biological samples, and clinical data to be catalogued at a single site. He...

    Authors: A Jamie Cuticchia, Philip C Cooley, R David Hall and Ying Qin

    Citation: BMC Medical Informatics and Decision Making 2006 6:19

    Content type: Database

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  10. Databases are frequently used for pharmacoepidemiological research. However, most of these databases consist either of prescribing, dispensing or administrative data and therefore lack insight in the interacti...

    Authors: Stefan R Florentinus, Patrick C Souverein, Fabiënne AMG Griens, Peter P Groenewegen, Hubert GM Leufkens and Eibert R Heerdink

    Citation: BMC Medical Informatics and Decision Making 2006 6:18

    Content type: Research article

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  13. Management of acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU) is clinically challenging and costly. Neuromuscular blocking agents may facilitate mechanical ventilation and improve o...

    Authors: Alex Macario, John L Chow and Franklin Dexter

    Citation: BMC Medical Informatics and Decision Making 2006 6:15

    Content type: Research article

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  14. Current practice guidelines offer different management recommendations for adults presenting with a sore throat. The key issue is the extent to which the clinical likelihood of a Group A streptococcal infectio...

    Authors: Sonal Singh, James G Dolan and Robert M Centor

    Citation: BMC Medical Informatics and Decision Making 2006 6:14

    Content type: Research article

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  15. Data mining can be utilized to automate analysis of substantial amounts of data produced in many organizations. However, data mining produces large numbers of rules and patterns, many of which are not useful. ...

    Authors: Mir S Siadaty and William A Knaus

    Citation: BMC Medical Informatics and Decision Making 2006 6:13

    Content type: Research article

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  16. Electronic medical records, including pathology reports, are often used for research purposes. Currently, there are few programs freely available to remove identifiers while leaving the remainder of the pathol...

    Authors: Bruce A Beckwith, Rajeshwarri Mahaadevan, Ulysses J Balis and Frank Kuo

    Citation: BMC Medical Informatics and Decision Making 2006 6:12

    Content type: Software

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  17. Approximately 30% of intubated preterm infants with respiratory distress syndrome (RDS) will fail attempted extubation, requiring reintubation and mechanical ventilation. Although ventilator technology and mon...

    Authors: Martina Mueller, Carol L Wagner, David J Annibale, Rebecca G Knapp, Thomas C Hulsey and Jonas S Almeida

    Citation: BMC Medical Informatics and Decision Making 2006 6:11

    Content type: Research article

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  19. In this study we propose the development of a new algorithm for selecting optimal recording sites for limited lead body surface potential mapping. The proposed algorithm differs from previously reported method...

    Authors: Dewar D Finlay, Chris D Nugent, Mark P Donnelly, Robert L Lux, Paul J McCullagh and Norman D Black

    Citation: BMC Medical Informatics and Decision Making 2006 6:9

    Content type: Technical advance

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  21. Categorization is designed to enhance resource description by organizing content description so as to enable the reader to grasp quickly and easily what are the main topics discussed in it. The objective of th...

    Authors: Stefan J Darmoni, Aurelie Névéol, Jean-Marie Renard, Jean-Francois Gehanno, Lina F Soualmia, Badisse Dahamna and Benoit Thirion

    Citation: BMC Medical Informatics and Decision Making 2006 6:7

    Content type: Research article

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  22. Real-time clinical decision support (CDS) integrated into clinicians' workflow has the potential to profoundly affect the cost, quality, and safety of health care delivery. Recent reports have identified a sur...

    Authors: Dean F Sittig, Michael A Krall, Richard H Dykstra, Allen Russell and Homer L Chin

    Citation: BMC Medical Informatics and Decision Making 2006 6:6

    Content type: Research article

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  24. Systematic reviews or randomised-controlled trials usually help to establish the effectiveness of drugs and other health technologies, but are rarely sufficient by themselves to ensure actual clinical use of t...

    Authors: Joseph Liu, Jeremy C Wyatt and Douglas G Altman

    Citation: BMC Medical Informatics and Decision Making 2006 6:4

    Content type: Debate

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  25. Factors of IT adoption have largely been discussed in the literature. However, existing frameworks (such as TAM or TTF) are failing to include one important aspect, the interaction between user and task.

    Authors: Elske Ammenwerth, Carola Iller and Cornelia Mahler

    Citation: BMC Medical Informatics and Decision Making 2006 6:3

    Content type: Research article

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  26. Robust, programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources are challenging to construct. Such systems require the adoption of comm...

    Authors: Joshua Phillips, Ram Chilukuri, Gilberto Fragoso, Denise Warzel and Peter A Covitz

    Citation: BMC Medical Informatics and Decision Making 2006 6:2

    Content type: Software

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  27. Comprehensive knowledge about the level of healthcare information technology (HIT) adoption in the United States remains limited. We therefore performed a baseline assessment to address this knowledge gap.

    Authors: Eric G Poon, Ashish K Jha, Melissa Christino, Melissa M Honour, Rushika Fernandopulle, Blackford Middleton, Joseph Newhouse, Lucian Leape, David W Bates, David Blumenthal and Rainu Kaushal

    Citation: BMC Medical Informatics and Decision Making 2006 6:1

    Content type: Research article

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  28. Tight glucose control by intensive insulin therapy has become a key part of critical care and is an important field of study in acute coronary care. A balance has to be found between frequency of measurements ...

    Authors: Mathijs Vogelzang, Felix Zijlstra and Maarten WN Nijsten

    Citation: BMC Medical Informatics and Decision Making 2005 5:38

    Content type: Research article

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  29. With the rapid growth of medical information and the pervasiveness of the Internet, online search and retrieval systems have become indispensable tools in medicine. The progress of Web technologies can provide...

    Authors: Michael Muin, Paul Fontelo, Fang Liu and Michael Ackerman

    Citation: BMC Medical Informatics and Decision Making 2005 5:37

    Content type: Software

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  30. Although colorectal cancer screening is recommended by major policy-making organizations, rates of screening remain low. Our aim was to develop a patient-directed, computer-based decision aid about colorectal ...

    Authors: Jane Kim, Annie Whitney, Sarah Hayter, Carmen Lewis, Marci Campbell, Lisa Sutherland, Beth Fowler, Sue Googe, Regina McCoy and Michael Pignone

    Citation: BMC Medical Informatics and Decision Making 2005 5:36

    Content type: Research article

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  34. Multiplication of data sources within heterogeneous healthcare information systems always results in redundant information, split among multiple databases. Our objective is to detect exact and approximate dupl...

    Authors: Erik A Sauleau, Jean-Philippe Paumier and Antoine Buemi

    Citation: BMC Medical Informatics and Decision Making 2005 5:32

    Content type: Research article

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  35. Theory-based approaches are advocated to improve our understanding of prescription behaviour. This study is an application of the theory of planned behaviour (TPB) with additional variables. It was designed to...

    Authors: France Legare, Gaston Godin, Virginie Ringa, Sylvie Dodin, Lucile Turcot and Joanna Norton

    Citation: BMC Medical Informatics and Decision Making 2005 5:31

    Content type: Research article

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  36. The medical problem list is an important part of the electronic medical record in development in our institution. To serve the functions it is designed for, the problem list has to be as accurate and timely as...

    Authors: Stephane Meystre and Peter J Haug

    Citation: BMC Medical Informatics and Decision Making 2005 5:30

    Content type: Research article

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  37. A common approach in exploring register data is to find relationships between outcomes and predictors by using multiple regression analysis (MRA). If there is more than one outcome variable, the analysis must ...

    Authors: Amir R Razavi, Hans Gill, Olle Stål, Marie Sundquist, Sten Thorstenson, Hans Åhlfeldt and Nosrat Shahsavar

    Citation: BMC Medical Informatics and Decision Making 2005 5:29

    Content type: Research article

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  38. The commercial development and expansion of mobile phone networks has led to the creation of devices combining mobile phones and personal digital assistants, which could prove invaluable in a clinical setting....

    Authors: Omer Aziz, Sukhmeet S Panesar, Gopalakrishnan Netuveli, Paraskevas Paraskeva, Aziz Sheikh and Ara Darzi

    Citation: BMC Medical Informatics and Decision Making 2005 5:28

    Content type: Research article

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  39. Notifiable disease surveillance in the United States is predominantly a passive process that is often limited by poor timeliness and low sensitivity. Interoperable tools are needed that interact more seamlessl...

    Authors: Timothy J Doyle, Haobo Ma, Samuel L Groseclose and Richard S Hopkins

    Citation: BMC Medical Informatics and Decision Making 2005 5:27

    Content type: Database

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  40. Pretest probability (PTP) assessment plays a central role in diagnosis. This report compares a novel attribute-matching method to generate a PTP for acute coronary syndrome (ACS). We compare the new method wit...

    Authors: Jeffrey A Kline, Charles L Johnson, Charles V Pollack Jr, Deborah B Diercks, Judd E Hollander, Craig D Newgard and J Lee Garvey

    Citation: BMC Medical Informatics and Decision Making 2005 5:26

    Content type: Research article

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  41. The AIDS and Cancer Specimen Resource (ACSR) is an HIV/AIDS tissue bank consortium sponsored by the National Cancer Institute (NCI) Division of Cancer Treatment and Diagnosis (DCTD). The ACSR offers to approve...

    Authors: David G Nohle, Barbara A Hackman and Leona W Ayers

    Citation: BMC Medical Informatics and Decision Making 2005 5:25

    Content type: Software

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  42. Understanding infant feeding practices in the context of HIV and factors that put mothers at risk of HIV infection is an important step towards prevention of mother to child transmission of HIV (PMTCT). Face-t...

    Authors: Anthony K Waruru, Ruth Nduati and Thorkild Tylleskär

    Citation: BMC Medical Informatics and Decision Making 2005 5:24

    Content type: Research article

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  43. Clinical practice guidelines are not uniformly successful in influencing clinicians' behaviour toward best practices. Implementability refers to a set of characteristics that predict ease of (and obstacles to)...

    Authors: Richard N Shiffman, Jane Dixon, Cynthia Brandt, Abdelwaheb Essaihi, Allen Hsiao, George Michel and Ryan O'Connell

    Citation: BMC Medical Informatics and Decision Making 2005 5:23

    Content type: Research article

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  44. Evaluating surveillance systems for the early detection of bioterrorism is particularly challenging when systems are designed to detect events for which there are few or no historical examples. One approach to...

    Authors: Christopher A Cassa, Karin Iancu, Karen L Olson and Kenneth D Mandl

    Citation: BMC Medical Informatics and Decision Making 2005 5:22

    Content type: Software

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  45. Although biomedical information is growing rapidly, it is difficult to find and retrieve validated data especially for rare hereditary diseases. There is an increased need for services capable of integrating a...

    Authors: Jouni Väliaho, Pentti Riikonen and Mauno Vihinen

    Citation: BMC Medical Informatics and Decision Making 2005 5:21

    Content type: Research article

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  46. With the information explosion, the retrieval of the best clinical evidence from large, general purpose, bibliographic databases such as MEDLINE can be difficult. Both researchers conducting systematic reviews...

    Authors: Nancy L Wilczynski, Douglas Morgan and R Brian Haynes

    Citation: BMC Medical Informatics and Decision Making 2005 5:20

    Content type: Study protocol

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  47. Public health departments in the United States are beginning to gain timely access to health data, often as soon as one day after a visit to a health care facility. Consequently, new approaches to outbreak sur...

    Authors: Karen L Olson, Marco Bonetti, Marcello Pagano and Kenneth D Mandl

    Citation: BMC Medical Informatics and Decision Making 2005 5:19

    Content type: Research article

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  48. The script concordance (SC) test is an assessment tool that measures capacity to solve ill-defined problems, that is, reasoning in context of uncertainty. This tool has been used up to now mainly in medicine. ...

    Authors: Louis Sibert, Stefan J Darmoni, Badisse Dahamna, Jacques Weber and Bernard Charlin

    Citation: BMC Medical Informatics and Decision Making 2005 5:18

    Content type: Research article

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  49. The objective of this study was to explore the use and perceptions of a local Severe Acute Respiratory Syndrome (SARS) Extranet and its potential to support future information and communication applications. T...

    Authors: Ruta K Valaitis, Noori Akhtar-Danesh, Cathy M Kealey, Glenn M Brunetti and Helen Thomas

    Citation: BMC Medical Informatics and Decision Making 2005 5:17

    Content type: Research article

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  50. Decision aids (DA) to assist patients in evaluating treatment options and sharing in decision making have proliferated in recent years. Most require high literacy and do not use plain language principles. We d...

    Authors: Margaret Holmes-Rovner, Sue Stableford, Angela Fagerlin, John T Wei, Rodney L Dunn, Janet Ohene-Frempong, Karen Kelly-Blake and David R Rovner

    Citation: BMC Medical Informatics and Decision Making 2005 5:16

    Content type: Research article

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