Articles

Implementation of shared decision-making in oncology: development and pilot study of a nurse-led decision-coaching programme for women with ductal carcinoma in situ

To implement informed shared decision-making (ISDM) in breast care centres, we developed and piloted an inter-professional complex intervention.

Authors: Birte Berger-Höger, Katrin Liethmann, Ingrid Mühlhauser and Anke Steckelberg

Recognizing difficult trade-offs: values and treatment preferences for end-of-life care in a multi-site survey of adult patients in family practices

Decisions about care options and the use of life-sustaining treatments should be informed by a person’s values and treatment preferences. The objective of this study was to examine the consistency of ratings o...

Authors: Michelle Howard, Nick Bansback, Amy Tan, Doug Klein, Carrie Bernard, Doris Barwich, Peter Dodek, Aman Nijjar and Daren K. Heyland

Autism risk classification using placental chorionic surface vascular network features

Autism Spectrum Disorder (ASD) is one of the fastest-growing developmental disorders in the United States. It was hypothesized that variations in the placental chorionic surface vascular network (PCSVN) struct...

Authors: Jen-Mei Chang, Hui Zeng, Ruxu Han, Ya-Mei Chang, Ruchit Shah, Carolyn M. Salafia, Craig Newschaffer, Richard K. Miller, Philip Katzman, Jack Moye, Margaret Fallin, Cheryl K. Walker and Lisa Croen

Development of a video-simulation instrument for assessing cognition in older adults

Commonly used methods to assess cognition, such as direct observation, self-report, or neuropsychological testing, have significant limitations. Therefore, a novel tablet computer-based video simulation was cr...

Authors: Edward H. Ip, Ryan Barnard, Sarah A. Marshall, Lingyi Lu, Kaycee Sink, Valerie Wilson, Dana Chamberlain and Stephen R. Rapp

The effect of nursing participation in the design of a critical care information system: a case study in a Chinese hospital

Intensive care information systems (ICIS) are continuously evolving to meet the ever changing information needs of intensive care units (ICUs), providing the backbone for a safe, intelligent and efficient pati...

Authors: Yanhong Qin, Ranyun Zhou, Qiong Wu, Xiaodi Huang, Xinli Chen, Weiwei Wang, Xun Wang, Hua Xu, Jing Zheng, Siyu Qian, Changqing Bai and Ping Yu

The development of a nursing subset of patient problems to support interoperability

Since the emergence of electronic health records, nursing information is increasingly being recorded and stored digitally. Several studies have shown that a wide range of nursing information is not interoperab...

Authors: R. A. M. M. Kieft, E. M. Vreeke, E. M. de Groot, P. A. Volkert, A. L. Francke and D. M. J. Delnoij

Validation of an algorithm that determines stroke diagnostic code accuracy in a Japanese hospital-based cancer registry using electronic medical records

This study aimed to validate an algorithm that determines stroke diagnostic code accuracy, in a hospital-based cancer registry, using electronic medical records (EMRs) in Japan.

Authors: Yasufumi Gon, Daijiro Kabata, Keichi Yamamoto, Ayumi Shintani, Kenichi Todo, Hideki Mochizuki and Manabu Sakaguchi

Exploring the feasibility of eHealth solutions to decrease delays in maternal healthcare in remote communities of Ghana

Despite the introduction of the Millennium Development Goal to reduce maternal deaths from 400 to 100 per 100,000 live births, the proportion of maternal deaths is still much higher in most developing countrie...

Authors: Pedro Pagalday-Olivares, Bengt Arne Sjöqvist, Jessy Adjordor-van de Beek, Samuel Abudey, Ants R. Silberberg and Ruben Buendia

Medical subdomain classification of clinical notes using a machine learning-based natural language processing approach

The medical subdomain of a clinical note, such as cardiology or neurology, is useful content-derived metadata for developing machine learning downstream applications. To classify the medical subdomain of a not...

Authors: Wei-Hung Weng, Kavishwar B. Wagholikar, Alexa T. McCray, Peter Szolovits and Henry C. Chueh

A mobile and web-based clinical decision support and monitoring system for diabetes mellitus patients in primary care: a study protocol for a randomized controlled trial

Physicians’ guideline use rates for diagnosis, treatment and monitoring of diabetes mellitus (DM) is very low. Time constraints, patient overpopulation, and complex guidelines require alternative solutions for...

Authors: Özge Kart, Vildan Mevsim, Alp Kut, İsmail Yürek, Ayşe Özge Altın and Oğuz Yılmaz

Patient perspectives on engagement in decision-making in early management of non-ST elevation acute coronary syndrome: a qualitative study

Surveys of patients suggest many want to be actively involved in treatment decisions for acute coronary syndromes. However, patient experiences of their engagement and participation in early phase decision-mak...

Authors: Todd Wilson, Jean Miller, Sylvia Teare, Colin Penman, Winnie Pearson, Nancy J. Marlett, Svetlana Shklarov, P. Diane Galbraith, Danielle A. Southern, Merril L. Knudtson, Colleen M. Norris, Matthew T. James and Stephen B. Wilton

Association between borderline dysnatremia and mortality insight into a new data mining approach

Even small variations of serum sodium concentration may be associated with mortality. Our objective was to confirm the impact of borderline dysnatremia for patients admitted to hospital on in-hospital mortalit...

Authors: Yannick Girardeau, Anne-Sophie Jannot, Gilles Chatellier and Olivier Saint-Jean

Experimental application of Business Process Management technology to manage clinical pathways: a pediatric kidney transplantation follow up case

To test the application of Business Process Management technology to manage clinical pathways, using a pediatric kidney transplantation as case study, and to identify the benefits obtained from using this tech...

Authors: Martina Andellini, Sandra Fernandez Riesgo, Federica Morolli, Matteo Ritrovato, Piero Cosoli, Silverio Petruzzellis and Nicola Rosso

Evaluation of data quality of interRAI assessments in home and community care

The aim of this project is to describe the quality of assessment data regularly collected in home and community, with techniques adapted from an evaluation of the quality of long-term care data in Canada.

Authors: Sophie E. Hogeveen, Jonathan Chen and John P. Hirdes

Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting

Multiple criteria decision analysis (MCDA) has appeared as a methodology to address limitations of economic evaluation in health technology assessment (HTA), however there are limited empirical evidence from r...

Authors: Aris Angelis, Gilberto Montibeller, Daniel Hochhauser and Panos Kanavos

EsPRit: ethics committee proposals for Long Term Medical Data Registries in rapidly evolving research fields - a future-proof best practice approach

Long-term data collection is a challenging task in the domain of medical research. Many effects in medicine require long periods of time to become traceable e.g. the development of secondary malignancies based...

Authors: S. Oberbichler, W. O. Hackl and A. Hörbst

Finnish physicians’ stress related to information systems keeps increasing: a longitudinal three-wave survey study

Poorly functioning, time-consuming, and inadequate information systems are among the most important work-related psychosocial factors causing stress in physicians. The present study examined the trend in the p...

Authors: Tarja Heponiemi, Hannele Hyppönen, Tuulikki Vehko, Sari Kujala, Anna-Mari Aalto, Jukka Vänskä and Marko Elovainio

Assessment of a Business-to-Consumer (B2C) model for Telemonitoring patients with Chronic Heart Failure (CHF)

The purpose of this study is to assess the Business-to-Consumer (B2C) model for telemonitoring patients with Chronic Heart Failure (CHF) by analysing the value it creates, both for organizations or ventures th...

Authors: Andrija S. Grustam, Hubertus J. M. Vrijhoef, Ron Koymans, Philipp Hukal and Johan L. Severens

Paramedic literature search filters: optimised for clinicians and academics

Search filters aid clinicians and academics to accurately locate literature. Despite this, there is no search filter or Medical Subject Headings (MeSH) term pertaining to paramedics. Therefore, the aim of this...

Authors: Alexander Olaussen, William Semple, Alaa Oteir, Paula Todd and Brett Williams

Decision support systems for incurable non-small cell lung cancer: a systematic review

Individually tailored cancer treatment is essential to ensure optimal treatment and resource use. Treatments for incurable metastatic non-small cell lung cancer (NSCLC) are evolving rapidly, and decision suppo...

Authors: D. Révész, E. G. Engelhardt, J. J. Tamminga, F. M. N. H. Schramel, B. D. Onwuteaka-Philipsen, E. M. W. van de Garde, E. W. Steyerberg, E. P. Jansma, H. C. W. De Vet and V. M. H. Coupé

A health app developer’s guide to law and policy: a multi-sector policy analysis

Apps targeted at health and wellbeing sit in a rapidly growing industry associated with widespread optimism about their potential to deliver accessible and cost-effective healthcare. App developers might not b...

Authors: Lisa Parker, Tanya Karliychuk, Donna Gillies, Barbara Mintzes, Melissa Raven and Quinn Grundy

A study protocol of the effectiveness of PEGASUS: a multi-centred study comparing an intervention to promote shared decision making about breast reconstruction with treatment as usual

Increasingly, women elect breast reconstruction after mastectomy. However, their expectations of surgery are often not met, and dissatisfaction with outcome and ongoing psychosocial concerns and distress are c...

Authors: Diana Harcourt, Nicole Paraskeva, Paul White, Jane Powell and Alex Clarke

Information needs for the rapid response team electronic clinical tool

Information overload in healthcare is dangerous. It can lead to critical errors and delays. During Rapid Response Team (RRT) activations providers must make decisions quickly to rescue patients from physiologi...

Authors: Amelia Barwise, Sean Caples, Jeffrey Jensen, Brian Pickering and Vitaly Herasevich

A novel data-driven workflow combining literature and electronic health records to estimate comorbidities burden for a specific disease: a case study on autoimmune comorbidities in patients with celiac disease

Data collected in EHRs have been widely used to identifying specific conditions; however there is still a need for methods to define comorbidities and sources to identify comorbidities burden. We propose an ap...

Authors: Jean-Baptiste Escudié, Bastien Rance, Georgia Malamut, Sherine Khater, Anita Burgun, Christophe Cellier and Anne-Sophie Jannot

Factors influencing the development of primary care data collection projects from electronic health records: a systematic review of the literature

Primary care data gathered from Electronic Health Records are of the utmost interest considering the essential role of general practitioners (GPs) as coordinators of patient care. These data represent the synt...

Authors: Marie-Line Gentil, Marc Cuggia, Laure Fiquet, Camille Hagenbourger, Thomas Le Berre, Agnès Banâtre, Eric Renault, Guillaume Bouzille and Anthony Chapron

The role and benefits of accessing primary care patient records during unscheduled care: a systematic review

The purpose of this study was to assess the impact of accessing primary care records on unscheduled care. Unscheduled care is typically delivered in hospital Emergency Departments. Studies published to Decembe...

Authors: Tom Bowden and Enrico Coiera

Communicating projected survival with treatments for chronic kidney disease: patient comprehension and perspectives on visual aids

Mortality in end stage renal disease (ESRD) is higher than many malignancies. There is no data about the optimal way to present information about projected survival to patients with ESRD. In other areas, graph...

Authors: Frances Dowen, Karishma Sidhu, Elizabeth Broadbent and Helen Pilmore

Internet use, eHealth literacy and attitudes toward computer/internet among people with schizophrenia spectrum disorders: a cross-sectional study in two distant European regions

Individuals with schizophrenia spectrum disorders use the Internet for general and health-related purposes. Their ability to find, understand, and apply the health information they acquire online in order to m...

Authors: Christina Athanasopoulou, Maritta Välimäki, Katerina Koutra, Eliisa Löttyniemi, Antonios Bertsias, Maria Basta, Alexandros N. Vgontzas and Christos Lionis

Risk factors of chronic periodontitis on healing response: a multilevel modelling analysis

Chronic periodontitis is a multifactorial polygenetic disease with an increasing number of associated factors that have been identified over recent decades. Longitudinal epidemiologic studies have demonstrated...

Authors: J. Song, H. Zhao, C. Pan, C. Li, J. Liu and Y. Pan

Dynamic-ETL: a hybrid approach for health data extraction, transformation and loading

Electronic health records (EHRs) contain detailed clinical data stored in proprietary formats with non-standard codes and structures. Participating in multi-site clinical research networks requires EHR data to...

Authors: Toan C. Ong, Michael G. Kahn, Bethany M. Kwan, Traci Yamashita, Elias Brandt, Patrick Hosokawa, Chris Uhrich and Lisa M. Schilling

Erratum to: development and testing of a mobile application to support diabetes self-management for people with newly diagnosed type 2 diabetes: a design thinking case study

Authors: Mira Petersen and Nana F. Hempler

Reviewing clinical guideline development tools: features and characteristics

To improve consistency and streamline development and publication of clinical guidelines (GL), there is a need for appropriate software support. We have found few specific tools for the actual authoring and ma...

Authors: Soudabeh Khodambashi and Øystein Nytrø

EXPLICIT: a feasibility study of remote expert elicitation in health technology assessment

Expert opinion is often sought to complement available information needed to inform model-based economic evaluations in health technology assessments. In this context, we define expert elicitation as the proce...

Authors: Bogdan Grigore, Jaime Peters, Christopher Hyde and Ken Stein

Evaluation of infectious diseases and clinical microbiology specialists’ preferences for hand hygiene: analysis using the multi-attribute utility theory and the analytic hierarchy process methods

Hand hygiene is one of the most effective attempts to control nosocomial infections, and it is an important measure to avoid the transmission of pathogens. However, the compliance of healthcare workers (HCWs) ...

Authors: Aslı Suner, Ozlem Ege Oruc, Cagri Buke, Hacer Deniz Ozkaya and Gul Kitapcioglu

Decision aids for second-line palliative chemotherapy: a randomised phase II multicentre trial

There is increasing recognition of the delicate balance between the modest benefits of palliative chemotherapy and the burden of treatment. Decision aids (DAs) can potentially help patients with advanced cance...

Authors: Linda J. M. Oostendorp, Petronella B. Ottevanger, A. Rogier T. Donders, Agnes J. van de Wouw, Ivonne J. H. Schoenaker, Tineke J. Smilde, Winette T. A. van der Graaf and Peep F. M. Stalmeier

Providing guidance for genomics-based cancer treatment decisions: insights from stakeholder engagement for post-prostatectomy radiation therapy

Despite the emergence of genomics-based risk prediction tools in oncology, there is not yet an established framework for communication of test results to cancer patients to support shared decision-making. We r...

Authors: James Abe, Jennifer M. Lobo, Daniel M. Trifiletti and Timothy N. Showalter

Empirical advances with text mining of electronic health records

Korian is a private group specializing in medical accommodations for elderly and dependent people. A professional data warehouse (DWH) established in 2010 hosts all of the residents’ data. Inside this informat...

Authors: T. Delespierre, P. Denormandie, A. Bar-Hen and L. Josseran

Unsatisfactory colposcopy: clinical decision-making in conditions of uncertainty

Unsatisfactory colposcopy, where the cells of interest are not visible in women with a positive cervical screening test, is a common area of clinical uncertainty due to the lack of clear evidence and guidance....

Authors: Kristyn M. Manley, Rebecca A. Simms, Sarah Platt, Amit Patel and Rachna Bahl

Word2Vec inversion and traditional text classifiers for phenotyping lupus

Identifying patients with certain clinical criteria based on manual chart review of doctors’ notes is a daunting task given the massive amounts of text notes in the electronic health records (EHR). This task c...

Authors: Clayton A. Turner, Alexander D. Jacobs, Cassios K. Marques, James C. Oates, Diane L. Kamen, Paul E. Anderson and Jihad S. Obeid

Examining database persistence of ISO/EN 13606 standardized electronic health record extracts: relational vs. NoSQL approaches

The objective of this research is to compare the relational and non-relational (NoSQL) database systems approaches in order to store, recover, query and persist standardized medical information in the form of ...

Authors: Ricardo Sánchez-de-Madariaga, Adolfo Muñoz, Raimundo Lozano-Rubí, Pablo Serrano-Balazote, Antonio L. Castro, Oscar Moreno and Mario Pascual

“Provoking conversations”: case studies of organizations where Option Grid™ decision aids have become ‘normalized’

Implementing patient decision aids in clinic workflow has proven to be a challenge for healthcare organizations and physicians. Our aim was to determine the organizational strategies, motivations, and facilita...

Authors: Peter Scalia, Glyn Elwyn and Marie-Anne Durand

Usability of data integration and visualization software for multidisciplinary pediatric intensive care: a human factors approach to assessing technology

Intensive care clinicians use several sources of data in order to inform decision-making. We set out to evaluate a new interactive data integration platform called T3™ made available for pediatric intensive ca...

Authors: Ying Ling Lin, Anne-Marie Guerguerian, Jessica Tomasi, Peter Laussen and Patricia Trbovich

A Fast Healthcare Interoperability Resources (FHIR) layer implemented over i2b2

Standards and technical specifications have been developed to define how the information contained in Electronic Health Records (EHRs) should be structured, semantically described, and communicated. Current tr...

Authors: Abdelali Boussadi and Eric Zapletal

Enhancement of hepatitis virus immunoassay outcome predictions in imbalanced routine pathology data by data balancing and feature selection before the application of support vector machines

Data mining techniques such as support vector machines (SVMs) have been successfully used to predict outcomes for complex problems, including for human health. Much health data is imbalanced, with many more co...

Authors: Alice M. Richardson and Brett A. Lidbury

Health care providers’ perceptions of use and influence of clinical decision support reminders: qualitative study following a randomized trial to improve HPV vaccination rates

Human Papillomavirus (HPV) leads to serious health issues and remains the most common sexually transmitted infection. Despite availability of effective vaccines, HPV vaccination rates are suboptimal. Furthermo...

Authors: Brian E. Dixon, Monica L. Kasting, Shannon Wilson, Amit Kulkarni, Gregory D. Zimet and Stephen M. Downs

Exploring differences in the use of the statin choice decision aid and diabetes medication choice decision aid in primary care

Shared decision making is essential to patient centered care, but can be difficult for busy clinicians to implement into practice. Tools have been developed to aid in shared decision making and embedded in ele...

Authors: Aimee Yu Ballard, Maya Kessler, Marianne Scheitel, Victor M. Montori and Rajeev Chaudhry

Developing a cardiovascular disease risk factor annotated corpus of Chinese electronic medical records

Cardiovascular disease (CVD) has become the leading cause of death in China, and most of the cases can be prevented by controlling risk factors. The goal of this study was to build a corpus of CVD risk factor ...

Authors: Jia Su, Bin He, Yi Guan, Jingchi Jiang and Jinfeng Yang

Routine health information system utilization and factors associated thereof among health workers at government health institutions in East Gojjam Zone, Northwest Ethiopia

Using reliable information from routine health information systems over time is an important aid to improving health outcomes, tackling disparities, enhancing efficiency, and encouraging innovation. In Ethiopi...

Authors: Atsede Mazengia Shiferaw, Dessalegn Tegabu Zegeye, Solomon Assefa and Melaku Kindie Yenit

Feature selection through validation and un-censoring of endovascular repair survival data for predicting the risk of re-intervention

Feature selection (FS) process is essential in the medical area as it reduces the effort and time needed for physicians to measure unnecessary features. Choosing useful variables is a difficult task with the p...

Authors: Omneya Attallah, Alan Karthikesalingam, Peter J. E. Holt, Matthew M. Thompson, Rob Sayers, Matthew J. Bown, Eddie C. Choke and Xianghong Ma

German dentists’ websites on periodontitis have low quality of information

The internet is an increasingly relevant source of health information. We aimed to assess the quality of German dentists’ websites on periodontitis, hypothesizing that it was significantly associated with a nu...

Authors: Falk Schwendicke, Jörg Stange, Claudia Stange and Christian Graetz