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  1. Routine surveillance of disease notification data can enable the early detection of localised disease outbreaks. Although hidden Markov models (HMMs) have been recognised as an appropriate method to model dise...

    Authors: Rochelle E Watkins, Serryn Eagleson, Bert Veenendaal, Graeme Wright and Aileen J Plant

    Citation: BMC Medical Informatics and Decision Making 2009 9:39

    Content type: Research article

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  2. The use of electronic health records (EHRs) to support the organization and delivery of healthcare is evolving rapidly. However, little is known regarding potential variation in access to EHRs by provider type...

    Authors: Margo C Orchard, Mark J Dobrow, Lawrence Paszat, Hedy Jiang and Patrick Brown

    Citation: BMC Medical Informatics and Decision Making 2009 9:38

    Content type: Research article

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  3. The penetration rate of Electronic Health Record (EHR) systems in health care is increasing. However, many different EHR-systems are used with varying ePrescription designs and functionalities. The aim of the ...

    Authors: Lina Hellström, Karolina Waern, Emelie Montelius, Bengt Åstrand, Tony Rydberg and Göran Petersson

    Citation: BMC Medical Informatics and Decision Making 2009 9:37

    Content type: Research article

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  4. The early identification of influenza outbreaks has became a priority in public health practice. A large variety of statistical algorithms for the automated monitoring of influenza surveillance have been propo...

    Authors: David Conesa, Antonio López-Quílez, Miguel Ángel Martínez-Beneito, María Teresa Miralles and Francisco Verdejo

    Citation: BMC Medical Informatics and Decision Making 2009 9:36

    Content type: Software

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  5. Health information technology (HIT) may improve health care quality and outcomes, in part by making information available in a timelier manner. However, there are few studies documenting the changes in timely ...

    Authors: Naomi S Bardach, Jie Huang, Richard Brand and John Hsu

    Citation: BMC Medical Informatics and Decision Making 2009 9:35

    Content type: Research article

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  6. The first step in practising Evidence Based Medicine (EBM) has been described as translating clinical uncertainty into a structured and focused clinical question that can be used to search the literature to as...

    Authors: Keith Lloyd, Matteo Cella, Michael Tanenblatt and Anni Coden

    Citation: BMC Medical Informatics and Decision Making 2009 9:34

    Content type: Research article

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  7. Exchange of Electronic Health Record (EHR) data between systems from different suppliers is a major challenge. EHR communication based on archetype methodology has been developed by openEHR and CEN/ISO. The ex...

    Authors: Rong Chen, Gunnar O Klein, Erik Sundvall, Daniel Karlsson and Hans Åhlfeldt

    Citation: BMC Medical Informatics and Decision Making 2009 9:33

    Content type: Research article

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  8. This paper presents the rationale for designing and implementing the next-generation of public health information systems using grid computing concepts and tools. Our attempt is to evaluate all grid types incl...

    Authors: Catherine J Staes, Wu Xu, Samuel D LeFevre, Ronald C Price, Scott P Narus, Adi Gundlapalli, Robert Rolfs, Barry Nangle, Matthew Samore and Julio C Facelli

    Citation: BMC Medical Informatics and Decision Making 2009 9:32

    Content type: Debate

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  9. Data protection is important for all information systems that deal with human-subjects data. Grid-based systems – such as the cancer Biomedical Informatics Grid (caBIG) – seek to develop new mechanisms to faci...

    Authors: Frank J Manion, Robert J Robbins, William A Weems and Rebecca S Crowley

    Citation: BMC Medical Informatics and Decision Making 2009 9:31

    Content type: Research article

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  10. Currently ambulatory patients break one in four tablets before ingestion. Roughly 10% of them are not suitable for splitting because they lack score lines or because enteric or modified release coating is dest...

    Authors: Renate Quinzler, Simon PW Schmitt, Maria Pritsch, Jens Kaltschmidt and Walter E Haefeli

    Citation: BMC Medical Informatics and Decision Making 2009 9:30

    Content type: Research article

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  11. Many hospital departments have implemented small clinical departmental systems (CDSs) to collect and use patient data for documentation as well as for other department-specific purposes. As hospitals are imple...

    Authors: Eivind Vedvik, Aksel H Tjora and Arild Faxvaag

    Citation: BMC Medical Informatics and Decision Making 2009 9:29

    Content type: Research article

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  12. Clinical guidelines carry medical evidence to the point of practice. As evidence is not always available, many guidelines do not provide recommendations for all clinical situations encountered in practice. We ...

    Authors: Massoud Toussi, Jean-Baptiste Lamy, Philippe Le Toumelin and Alain Venot

    Citation: BMC Medical Informatics and Decision Making 2009 9:28

    Content type: Research article

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  13. The outcome of patients with bacteraemia is influenced by the initial selection of adequate antimicrobial therapy. The objective of our study was to clarify the influence of different crude data correction met...

    Authors: Ojan Assadian, Magda Diab-Elschahawi, Athanasios Makristathis, Alexander Blacky, Walter Koller and Klaus-Peter Adlassnig

    Citation: BMC Medical Informatics and Decision Making 2009 9:27

    Content type: Research article

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  14. Newborn screening, which identifies inherited disorders and sometimes carrier status, will increasingly involve health professionals in the provision of appropriate information and support to children and thei...

    Authors: Fiona Ulph, Ellen Townsend and Cris Glazebrook

    Citation: BMC Medical Informatics and Decision Making 2009 9:26

    Content type: Research article

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  15. Revised consensus sepsis definitions have been published in 2003. The present study was performed to compare the prevalence of different stages of sepsis and ICU mortality rates and find out the case mix withi...

    Authors: Manfred Weiss, Markus Huber-Lang, Michael Taenzer, Karl Traeger, Juergen Altherr, Martina Kron, Birgit Hay and Marion Schneider

    Citation: BMC Medical Informatics and Decision Making 2009 9:25

    Content type: Research article

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  16. Individuals claiming a disability benefit after long-term sickness absence, have to undergo medical disability assessments. These assessments, often carried out by specialized physicians, can be complicated by...

    Authors: David Samoocha, David J Bruinvels, Johannes R Anema, Romy Steenbeek and Allard J van der Beek

    Citation: BMC Medical Informatics and Decision Making 2009 9:23

    Content type: Study protocol

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  17. Chronic diseases affect millions of children worldwide leading to substantial disease burden to the children and their families as well as escalating health care costs. The increasing trend in the prevalence o...

    Authors: Fatemeh Moeinedin, Rahim Moineddin, Alejandro R Jadad, Jemila S Hamid, Teresa To and Joseph Beyene

    Citation: BMC Medical Informatics and Decision Making 2009 9:22

    Content type: Research article

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  18. Public health surveillance is the monitoring of data to detect and quantify unusual health events. Monitoring pre-diagnostic data, such as emergency department (ED) patient chief complaints, enables rapid dete...

    Authors: Ryan P Hafen, David E Anderson, William S Cleveland, Ross Maciejewski, David S Ebert, Ahmad Abusalah, Mohamed Yakout, Mourad Ouzzani and Shaun J Grannis

    Citation: BMC Medical Informatics and Decision Making 2009 9:21

    Content type: Research article

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  19. This paper by John D. Keen and James E. Keen addresses a thorny subject. The numerical findings and commentaries in their paper will be disturbing to some readers and seem to defy logic and well established vi...

    Authors: Michael Retsky

    Citation: BMC Medical Informatics and Decision Making 2009 9:20

    Content type: Commentary

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  20. We analyzed the claim "mammography saves lives" by calculating the life-saving absolute benefit of screening mammography in reducing breast cancer mortality in women ages 40 to 65.

    Authors: John D Keen and James E Keen

    Citation: BMC Medical Informatics and Decision Making 2009 9:18

    Content type: Research article

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  21. In recent years, the completion of the Human Genome Project and other rapid advances in genomics have led to increasing anticipation of an era of genomic and personalized medicine, in which an individual's hea...

    Authors: Kensaku Kawamoto, David F Lobach, Huntington F Willard and Geoffrey S Ginsburg

    Citation: BMC Medical Informatics and Decision Making 2009 9:17

    Content type: Debate

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  22. A timely detection of outbreaks through surveillance is needed in order to prevent future pandemics. However, current surveillance systems may not be prepared to accomplish this goal, especially in resource li...

    Authors: Moises A Huaman, Roger V Araujo-Castillo, Giselle Soto, Joan M Neyra, Jose A Quispe, Miguel F Fernandez, Carmen C Mundaca and David L Blazes

    Citation: BMC Medical Informatics and Decision Making 2009 9:16

    Content type: Research article

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  23. Adoption of EHRs by U.S. ambulatory practices has been slow despite the perceived benefits of their use. Most evaluations of EHR implementations in the literature apply to large practice settings. While there ...

    Authors: Nancy M Lorenzi, Angelina Kouroubali, Don E Detmer and Meryl Bloomrosen

    Citation: BMC Medical Informatics and Decision Making 2009 9:15

    Content type: Debate

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  24. The health impacts of heat waves are serious and have prompted the development of heat wave response plans. Even when they are efficient, these plans are developed to limit the health effects of heat waves. Th...

    Authors: Loïc Josseran, Nadège Caillère, Dominique Brun-Ney, Jean Rottner, Laurent Filleul, Gilles Brucker and Pascal Astagneau

    Citation: BMC Medical Informatics and Decision Making 2009 9:14

    Content type: Research article

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  25. With wide applications of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TO...

    Authors: Yuan Cao, Na Wang, Xiaomin Ying, Ailing Li, Hengsha Wang, Xuemin Zhang and Wuju Li

    Citation: BMC Medical Informatics and Decision Making 2009 9:13

    Content type: Software

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  26. Computerized decision support systems (CDSS) are believed to have the potential to improve the quality of health care delivery, although results from high quality studies have been mixed. We conducted a system...

    Authors: Brent Mollon, Jaron JR Chong, Anne M Holbrook, Melani Sung, Lehana Thabane and Gary Foster

    Citation: BMC Medical Informatics and Decision Making 2009 9:11

    Content type: Research article

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  27. The practice of evidence-based medicine (EBM) requires clinicians to integrate their expertise with the latest scientific research. But this is becoming increasingly difficult with the growing numbers of publi...

    Authors: Grace Y Chung

    Citation: BMC Medical Informatics and Decision Making 2009 9:10

    Content type: Research article

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  28. Investing in computer-based information systems is notoriously risky, since many systems fail to become routinely used as part of everyday working practices, yet there is clear evidence about the management pr...

    Authors: David Boddy, Gerry King, Julia S Clark, David Heaney and Frances Mair

    Citation: BMC Medical Informatics and Decision Making 2009 9:9

    Content type: Research article

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  29. The introduction of electronic transfer of prescriptions (ETP) or ePrescriptions in ambulatory health care has been suggested to have a positive impact on the prescribing and dispensing processes. Thereby, imp...

    Authors: Bengt Åstrand, Emelie Montelius, Göran Petersson and Anders Ekedahl

    Citation: BMC Medical Informatics and Decision Making 2009 9:8

    Content type: Research article

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  30. The purpose of this study is to identify publication output, and research areas, as well as descriptively and quantitatively characterize the field of medical informatics through publication trend analysis ove...

    Authors: Jonathan P DeShazo, Donna L LaVallie and Fredric M Wolf

    Citation: BMC Medical Informatics and Decision Making 2009 9:7

    Content type: Research article

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  31. Despite wide promotion, clinical practice guidelines have had limited effect in changing physician behavior. Effective implementation strategies to date have included: multifaceted interventions involving audi...

    Authors: Madhukar H Trivedi, Ella J Daly, Janet K Kern, Bruce D Grannemann, Prabha Sunderajan and Cynthia A Claassen

    Citation: BMC Medical Informatics and Decision Making 2009 9:6

    Content type: Research article

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  32. Timely and accurate information is important to guide the medical treatment process. We developed, implemented and assessed an order-entry system to support documentation of prostate histologies involving urol...

    Authors: Bernhard Breil, Axel Semjonow and Martin Dugas

    Citation: BMC Medical Informatics and Decision Making 2009 9:5

    Content type: Research article

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  33. Vast amounts of data are collected about patients and service users in the course of health and social care service delivery. Electronic data systems for patient records have the potential to revolutionise ser...

    Authors: Ronan A Lyons, Kerina H Jones, Gareth John, Caroline J Brooks, Jean-Philippe Verplancke, David V Ford, Ginevra Brown and Ken Leake

    Citation: BMC Medical Informatics and Decision Making 2009 9:3

    Content type: Research article

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  34. This paper focuses on the creation of a predictive computer-assisted decision making system for traumatic injury using machine learning algorithms. Trauma experts must make several difficult decisions based on...

    Authors: Soo-Yeon Ji, Rebecca Smith, Toan Huynh and Kayvan Najarian

    Citation: BMC Medical Informatics and Decision Making 2009 9:2

    Content type: Research article

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  35. Pretreatment auxological variables, such as birth size and parental heights, are important predictors of the growth response to GH treatment. For children with missing pretreatment data, published prediction m...

    Authors: Berit Kriström, Jovanna Dahlgren, Aimon Niklasson, Andreas FM Nierop and Kerstin Albertsson-Wikland

    Citation: BMC Medical Informatics and Decision Making 2009 9:1

    Content type: Research article

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  36. New legal regulations for the marketing of pharmaceutical products were introduced in 2002 in Switzerland. We investigated whether claims in drug advertisements citing published scientific studies were justifi...

    Authors: Macarena Gonzalez Santiago, Heiner C Bucher and Alain J Nordmann

    Citation: BMC Medical Informatics and Decision Making 2008 8:61

    Content type: Correspondence

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  37. Despite the pressing need for the creation of applications that facilitate the aggregation of clinical and molecular data, most current applications are proprietary and lack the necessary compliance with stand...

    Authors: Patrick McConnell, Rajesh C Dash, Ram Chilukuri, Ricardo Pietrobon, Kimberly Johnson, Robert Annechiarico and A Jamie Cuticchia

    Citation: BMC Medical Informatics and Decision Making 2008 8:60

    Content type: Software

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  38. While many factors can influence the way that cancer care is delivered, including the way that evidence is packaged and disseminated, little research has evaluated how health care professionals who manage canc...

    Authors: Anna R Gagliardi, Frances C Wright, Dave Davis, Robin S McLeod and David R Urbach

    Citation: BMC Medical Informatics and Decision Making 2008 8:59

    Content type: Research article

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  39. First generation Internet technologies such as mailing lists or newsgroups afforded unprecedented levels of information exchange within a variety of interest groups, including those who seek health information...

    Authors: Laura A O'Grady, Holly Witteman and C Nadine Wathen

    Citation: BMC Medical Informatics and Decision Making 2008 8:58

    Content type: Correspondence

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  40. Common dental procedures induce bacteremia. To prevent infectious complications from bacteremia in patients with specific medical conditions, antibiotic prophylaxis is considered. Recommendations are often unc...

    Authors: Eva Ellervall, Berndt Brehmer and Kerstin Knutsson

    Citation: BMC Medical Informatics and Decision Making 2008 8:57

    Content type: Research article

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  41. Several models for mortality prediction have been constructed for critically ill patients with haematological malignancies in recent years. These models have proven to be equally or more accurate in predicting...

    Authors: T Verplancke, S Van Looy, D Benoit, S Vansteelandt, P Depuydt, F De Turck and J Decruyenaere

    Citation: BMC Medical Informatics and Decision Making 2008 8:56

    Content type: Research article

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  42. Diabetic type 1 patients are often advised to use dose adjustment guidelines to calculate their doses of insulin. Conventional methods of measuring patients' adherence are not applicable to these cases, becaus...

    Authors: Massoud Toussi, Carine Choleau, Gérard Reach, Michel Cahané, Avner Bar-Hen and Alain Venot

    Citation: BMC Medical Informatics and Decision Making 2008 8:55

    Content type: Research article

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  43. Chronic disease management is a global health concern. By the time they reach adolescence, 10–15% of all children live with a chronic disease. The role of educational interventions in facilitating adaptation t...

    Authors: Toomas Timpka, Henrik Eriksson, Johnny Ludvigsson, Joakim Ekberg, Sam Nordfeldt and Lena Hanberger

    Citation: BMC Medical Informatics and Decision Making 2008 8:54

    Content type: Research article

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  44. Decision curve analysis is a novel method for evaluating diagnostic tests, prediction models and molecular markers. It combines the mathematical simplicity of accuracy measures, such as sensitivity and specifi...

    Authors: Andrew J Vickers, Angel M Cronin, Elena B Elkin and Mithat Gonen

    Citation: BMC Medical Informatics and Decision Making 2008 8:53

    Content type: Technical advance

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  45. The present work aims at the application of the decision theory to radiological image quality control (QC) in diagnostic routine. The main problem addressed in the framework of decision theory is to accept or ...

    Authors: Patrícia S Lessa, Cristofer A Caous, Paula R Arantes, Edson Amaro Jr and Fernando M Campello de Souza

    Citation: BMC Medical Informatics and Decision Making 2008 8:51

    Content type: Research article

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