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Clinical decision-making, knowledge support systems, and theory

Section edited by Paul Taylor

This section aims to publish studies on the development, implementation and evaluation of clinical decision support systems. The section also accepts articles on the theoretical support of clinical decision-making (including shared-decision making), decision analysis, and decision aids.

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  1. Colorectal cancer (CRC) screening has shown to reduce incidence and mortality rates, and therefore is widely recommended for people above 50 years-old. However, despite the implementation of population-based s...

    Authors: Lilisbeth Perestelo-Perez, Amado Rivero-Santana, Alezandra Torres-Castaño, Vanesa Ramos-Garcia, Yolanda Alvarez-Perez, Nerea Gonzalez-Hernandez, Andrea Buron, Michael Pignone and Pedro Serrano-Aguilar

    Citation: BMC Medical Informatics and Decision Making 2019 19:8

    Content type: Research article

    Published on:

  2. Machine-learning classifiers mostly offer good predictive performance and are increasingly used to support shared decision-making in clinical practice. Focusing on performance and practicability, this study ev...

    Authors: Manuel Huber, Christoph Kurz and Reiner Leidl

    Citation: BMC Medical Informatics and Decision Making 2019 19:3

    Content type: Research article

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  3. The Cancer of the Prostate Risk Assessment (CAPRA) score was designed and validated several times to predict the biochemical recurrence-free survival after a radical prostatectomy. Our objectives were, first, ...

    Authors: Marine Lorent, Haïfa Maalmi, Philippe Tessier, Stéphane Supiot, Etienne Dantan and Yohann Foucher

    Citation: BMC Medical Informatics and Decision Making 2019 19:2

    Content type: Research article

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  4. Breast cancer chemoprevention can reduce breast cancer incidence in high-risk women; however, chemoprevention is underutilized in the primary care setting. We conducted a pilot study of decision support tools ...

    Authors: Rita Kukafka, Jiaqi Fang, Alejandro Vanegas, Thomas Silverman and Katherine D. Crew

    Citation: BMC Medical Informatics and Decision Making 2018 18:134

    Content type: Research article

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  5. Decision-making about palliative care for metastatic colorectal cancer (mCRC) consists of many different treatment-related decisions, and there generally is no best treatment option. Decision support systems (...

    Authors: Ellen G. Engelhardt, Dóra Révész, Hans J. Tamminga, Cornelis J. A. Punt, Miriam Koopman, Bregje D. Onwuteaka-Philipsen, Ewout W. Steyerberg, Henrica C. W. de Vet and Veerle M. H. Coupé

    Citation: BMC Medical Informatics and Decision Making 2018 18:132

    Content type: Research article

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  6. As of 2014, stroke is the fourth leading cause of death in Japan. Predicting a future diagnosis of stroke would better enable proactive forms of healthcare measures to be taken. We aim to predict a diagnosis o...

    Authors: Douglas Teoh

    Citation: BMC Medical Informatics and Decision Making 2018 18:127

    Content type: Technical advance

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  7. Common measures used to describe preventive treatment effects today are proportional, i.e. they compare the proportions of events in relative or absolute terms, however they are not easily interpreted from the...

    Authors: Erik Berglund, Ragnar Westerling, Johan Sundström and Per Lytsy

    Citation: BMC Medical Informatics and Decision Making 2018 18:106

    Content type: Research article

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  8. To identify publicly available internet resources and assess their likelihood to support women making informed decisions about, and between, fertility preservation procedures before starting their cancer treat...

    Authors: N. Mahmoodi, H. L. Bekker, N. V. King, J. Hughes and G. L. Jones

    Citation: BMC Medical Informatics and Decision Making 2018 18:104

    Content type: Research article

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  9. The National Sleep Research Resource (NSRR) is a large-scale, openly shared, data repository of de-identified, highly curated clinical sleep data from multiple NIH-funded epidemiological studies. Although many...

    Authors: Licong Cui, Ningzhou Zeng, Matthew Kim, Remo Mueller, Emily R. Hankosky, Susan Redline and Guo-Qiang Zhang

    Citation: BMC Medical Informatics and Decision Making 2018 18:99

    Content type: Research article

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  10. Headache disorders are an important health burden, having a large health-economic impact worldwide. Current treatment & follow-up processes are often archaic, creating opportunities for computer-aided and deci...

    Authors: Gilles Vandewiele, Femke De Backere, Kiani Lannoye, Maarten Vanden Berghe, Olivier Janssens, Sofie Van Hoecke, Vincent Keereman, Koen Paemeleire, Femke Ongenae and Filip De Turck

    Citation: BMC Medical Informatics and Decision Making 2018 18:98

    Content type: Research article

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  11. Technological support may be crucial in optimizing healthcare professional practice and improving patient outcomes. A focus on electronic health records has left other technological supports relatively neglect...

    Authors: C Keyworth, J Hart, C J Armitage and M P Tully

    Citation: BMC Medical Informatics and Decision Making 2018 18:93

    Content type: Research article

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  12. Trio studies, which involve the testing of samples from a proband and both parents, are often used by clinical laboratories to help with the classification of genetic variants, including copy number variants. ...

    Authors: Daniel Xia, Chen Zhang, Va Lip, Marian Harris and Yiping Shen

    Citation: BMC Medical Informatics and Decision Making 2018 18:91

    Content type: Software

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  13. The health area is one of the most affected systems on the perspective of decision-making with multiobjectives, thus becoming prone to errors in the final solution, however, multicriteria decision analysis (MD...

    Authors: Talita D. C. Frazão, Deyse G. G. Camilo, Eric L. S. Cabral and Ricardo P. Souza

    Citation: BMC Medical Informatics and Decision Making 2018 18:90

    Content type: Research article

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  14. Molecular precision oncology is an emerging practice to improve cancer therapy by decreasing the risk of choosing treatments that lack efficacy or cause adverse events. However, the challenges of integrating m...

    Authors: Franziska Singer, Anja Irmisch, Nora C. Toussaint, Linda Grob, Jochen Singer, Thomas Thurnherr, Niko Beerenwinkel, Mitchell P. Levesque, Reinhard Dummer, Luca Quagliata, Sacha I. Rothschild, Andreas Wicki, Christian Beisel and Daniel J. Stekhoven

    Citation: BMC Medical Informatics and Decision Making 2018 18:89

    Content type: Research article

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  15. Patients suffering obstructive sleep apnea are mainly treated with continuous positive airway pressure (CPAP). Although it is a highly effective treatment, compliance with this therapy is problematic to achiev...

    Authors: Xavier Rafael-Palou, Cecilia Turino, Alexander Steblin, Manuel Sánchez-de-la-Torre, Ferran Barbé and Eloisa Vargiu

    Citation: BMC Medical Informatics and Decision Making 2018 18:81

    Content type: Research article

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  16. Usability flaws in medication alerting systems may have a negative impact on clinical use and patient safety. In order to prevent the release of alerting systems that contain such flaws, it is necessary to pro...

    Authors: Romaric Marcilly, Elske Ammenwerth, Erin Roehrer, Julie Niès and Marie-Catherine Beuscart-Zéphir

    Citation: BMC Medical Informatics and Decision Making 2018 18:69

    Content type: Research article

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  17. The use of knowledge models facilitates information retrieval, knowledge base development, and therefore supports new knowledge discovery that ultimately enables decision support applications. Most existing wo...

    Authors: Yiqing Zhao, Nooshin J. Fesharaki, Hongfang Liu and Jake Luo

    Citation: BMC Medical Informatics and Decision Making 2018 18:61

    Content type: Research article

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  18. Approaches to nurse staffing are commonly concerned with determining the minimum number of care hours according to the illness severity of patients. However, there is a gap in the literature considering multi-...

    Authors: Ana Respicio, Margarida Moz, Margarida Vaz Pato, Rute Somensi and Cecília Dias Flores

    Citation: BMC Medical Informatics and Decision Making 2018 18:53

    Content type: Research article

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  19. Despite the growing interest in developing markers for predicting treatment response and optimizing treatment decisions, an appropriate methodology to identify, combine and evaluate such markers has been slow ...

    Authors: Parvin Tajik, Mohammad Hadi Zafarmand, Aeilko H. Zwinderman, Ben W. Mol and Patrick M. Bossuyt

    Citation: BMC Medical Informatics and Decision Making 2018 18:52

    Content type: Technical advance

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  20. The performance of Computer Aided Diagnosis Systems for early melanoma detection relies mainly on quantitative evaluation of the geometric features corresponding to skin lesions. In these systems, diagnosis is...

    Authors: Agustin Sancen-Plaza, Raul Santiago-Montero, Humberto Sossa, Francisco J. Perez-Pinal, Juan J. Martinez-Nolasco and Jose A. Padilla-Medina

    Citation: BMC Medical Informatics and Decision Making 2018 18:50

    Content type: Research article

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  21. As patients become more engaged in decisions regarding their medical care, they must weigh the potential benefits and harms of different treatments. Patients who are low in numeracy may be at a disadvantage wh...

    Authors: Rachel F. Eyler, Sara Cordes, Benjamin R. Szymanski and Liana Fraenkel

    Citation: BMC Medical Informatics and Decision Making 2018 18:40

    Content type: Research article

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  22. It is essential that cancer patients understand anticipated symptoms, how to self-manage these symptoms, and when to call their clinicians. However, patients are often ill-prepared to manage symptoms at home. ...

    Authors: Mary E. Cooley, Janet L. Abrahm, Donna L. Berry, Michael S. Rabin, Ilana M. Braun, Joanna Paladino, Manan M. Nayak and David F. Lobach

    Citation: BMC Medical Informatics and Decision Making 2018 18:31

    Content type: Research article

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  23. Pathology reports are written in free-text form, which precludes efficient data gathering. We aimed to overcome this limitation and design an automated system for extracting biomarker profiles from accumulated...

    Authors: Jeongeun Lee, Hyun-Je Song, Eunsil Yoon, Seong-Bae Park, Sung-Hye Park, Jeong-Wook Seo, Peom Park and Jinwook Choi

    Citation: BMC Medical Informatics and Decision Making 2018 18:29

    Content type: Research article

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  24. Although evidence-based practice in healthcare has been facilitated by Internet access through wireless mobile devices, research on the effectiveness of clinical decision support for clinicians at the point of...

    Authors: Kyungsook Gartrell, Caitlin W. Brennan, Gwenyth R. Wallen, Fang Liu, Karen G. Smith and Paul Fontelo

    Citation: BMC Medical Informatics and Decision Making 2018 18:27

    Content type: Research article

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  25. The use of measurement instruments has become a major issue in physical therapy, but their use in daily practice is rare. The aim of this paper is to describe adherence to standardized assessments by physical ...

    Authors: Tania Gutiérrez Panchana and Viviane Hidalgo Cabalín

    Citation: BMC Medical Informatics and Decision Making 2018 18:21

    Content type: Research article

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  26. The frequency of head computed tomography (CT) imaging for mild head trauma patients has raised safety and cost concerns. Validated clinical decision rules exist in the published literature and on-line sources...

    Authors: Ronald W. Gimbel, Ronald G. Pirrallo, Steven C. Lowe, David W. Wright, Lu Zhang, Min-Jae Woo, Paul Fontelo, Fang Liu and Zachary Connor

    Citation: BMC Medical Informatics and Decision Making 2018 18:20

    Content type: Research article

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  27. Traditional Chinese Medicine (TCM) is a style of traditional medicine informed by modern medicine but built on a foundation of more than 2500 years of Chinese medical practice. According to statistics, TCM acc...

    Authors: Jian-Xiang Wei, Jing Wang, Yun-Xia Zhu, Jun Sun, Hou-Ming Xu and Ming Li

    Citation: BMC Medical Informatics and Decision Making 2018 18:19

    Content type: Research article

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  28. Patient portals are considered valuable instruments for self-management of long term conditions, however, there are concerns over how patients might interpret and act on the clinical information they access. W...

    Authors: Paolo Fraccaro, Markel Vigo, Panagiotis Balatsoukas, Sabine N. van der Veer, Lamiece Hassan, Richard Williams, Grahame Wood, Smeeta Sinha, Iain Buchan and Niels Peek

    Citation: BMC Medical Informatics and Decision Making 2018 18:11

    Content type: Research article

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  29. The United States Preventive Services Task Force (USPSTF) issued recommendations for older, heavy lifetime smokers to complete annual low-dose computed tomography (LDCT) scans of the chest as screening for lun...

    Authors: Daniel S. Reuland, Laura Cubillos, Alison T. Brenner, Russell P. Harris, Bailey Minish and Michael P. Pignone

    Citation: BMC Medical Informatics and Decision Making 2018 18:5

    Content type: Research article

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  30. The evolving role of pharmacists in providing pharmaceutical care, as part of the healthcare team, challenges them to acquire up-to-date knowledge of medicines to make the best clinical decisions. The volume o...

    Authors: Ali Jasem Buabbas, Fatemah Mohammad Alsaleh, Hamza Mohamad Al-Shawaf, Ali Abdullah and Abdullah Almajran

    Citation: BMC Medical Informatics and Decision Making 2018 18:4

    Content type: Research article

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  31. The identification of patients at high risk of unplanned readmission is an important component of discharge planning strategies aimed at preventing unwanted returns to hospital. The aim of this study was to in...

    Authors: Yashar Maali, Oscar Perez-Concha, Enrico Coiera, David Roffe, Richard O. Day and Blanca Gallego

    Citation: BMC Medical Informatics and Decision Making 2018 18:1

    Content type: Research article

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  32. We studied the impact of a clinical decision support system (CDSS) implemented in a few wards of two Italian health care organizations on the ordering of redundant laboratory tests under different perspectives...

    Authors: Elena Bellodi, Emidia Vagnoni, Barbara Bonvento and Evelina Lamma

    Citation: BMC Medical Informatics and Decision Making 2017 17:179

    Content type: Research article

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  33. Little research has examined how physicians choose medical devices for treating individual patients to reveal if interventions are needed to support decision-making and reduce device-associated morbidity and m...

    Authors: Anna R. Gagliardi, Ariel Ducey, Pascale Lehoux, Thomas Turgeon, Jeremy Kolbunik, Sue Ross, Patricia Trbovich, Anthony Easty, Chaim Bell and David R. Urbach

    Citation: BMC Medical Informatics and Decision Making 2017 17:178

    Content type: Research article

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  34. It is beneficial for health care institutions to monitor physician prescribing patterns to ensure that high-quality and cost-effective care is being provided to patients. However, detecting treatment patterns ...

    Authors: Daniel Backenroth, Herbert S. Chase, Ying Wei and Carol Friedman

    Citation: BMC Medical Informatics and Decision Making 2017 17:175

    Content type: Technical advance

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  35. Safety checklist is a type of cognitive tool enforcing short term memory of medical workers with the purpose of reducing medical errors caused by overlook and ignorance. To facilitate the daily use of safety c...

    Authors: Shan Nan, Pieter Van Gorp, Xudong Lu, Uzay Kaymak, Hendrikus Korsten, Richard Vdovjak and Huilong Duan

    Citation: BMC Medical Informatics and Decision Making 2017 17:170

    Content type: Research article

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  36. Decisions about care options and the use of life-sustaining treatments should be informed by a person’s values and treatment preferences. The objective of this study was to examine the consistency of ratings o...

    Authors: Michelle Howard, Nick Bansback, Amy Tan, Doug Klein, Carrie Bernard, Doris Barwich, Peter Dodek, Aman Nijjar and Daren K. Heyland

    Citation: BMC Medical Informatics and Decision Making 2017 17:164

    Content type: Research article

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  37. To implement informed shared decision-making (ISDM) in breast care centres, we developed and piloted an inter-professional complex intervention.

    Authors: Birte Berger-Höger, Katrin Liethmann, Ingrid Mühlhauser and Anke Steckelberg

    Citation: BMC Medical Informatics and Decision Making 2017 17:160

    Content type: Research article

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  38. This study aimed to validate an algorithm that determines stroke diagnostic code accuracy, in a hospital-based cancer registry, using electronic medical records (EMRs) in Japan.

    Authors: Yasufumi Gon, Daijiro Kabata, Keichi Yamamoto, Ayumi Shintani, Kenichi Todo, Hideki Mochizuki and Manabu Sakaguchi

    Citation: BMC Medical Informatics and Decision Making 2017 17:157

    Content type: Research article

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  39. Physicians’ guideline use rates for diagnosis, treatment and monitoring of diabetes mellitus (DM) is very low. Time constraints, patient overpopulation, and complex guidelines require alternative solutions for...

    Authors: Özge Kart, Vildan Mevsim, Alp Kut, İsmail Yürek, Ayşe Özge Altın and Oğuz Yılmaz

    Citation: BMC Medical Informatics and Decision Making 2017 17:154

    Content type: Study protocol

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  40. Surveys of patients suggest many want to be actively involved in treatment decisions for acute coronary syndromes. However, patient experiences of their engagement and participation in early phase decision-mak...

    Authors: Todd Wilson, Jean Miller, Sylvia Teare, Colin Penman, Winnie Pearson, Nancy J. Marlett, Svetlana Shklarov, P. Diane Galbraith, Danielle A. Southern, Merril L. Knudtson, Colleen M. Norris, Matthew T. James and Stephen B. Wilton

    Citation: BMC Medical Informatics and Decision Making 2017 17:153

    Content type: Research article

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  41. Multiple criteria decision analysis (MCDA) has appeared as a methodology to address limitations of economic evaluation in health technology assessment (HTA), however there are limited empirical evidence from r...

    Authors: Aris Angelis, Gilberto Montibeller, Daniel Hochhauser and Panos Kanavos

    Citation: BMC Medical Informatics and Decision Making 2017 17:149

    Content type: Research article

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  42. Individually tailored cancer treatment is essential to ensure optimal treatment and resource use. Treatments for incurable metastatic non-small cell lung cancer (NSCLC) are evolving rapidly, and decision suppo...

    Authors: D. Révész, E. G. Engelhardt, J. J. Tamminga, F. M. N. H. Schramel, B. D. Onwuteaka-Philipsen, E. M. W. van de Garde, E. W. Steyerberg, E. P. Jansma, H. C. W. De Vet and V. M. H. Coupé

    Citation: BMC Medical Informatics and Decision Making 2017 17:144

    Content type: Research article

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  43. Increasingly, women elect breast reconstruction after mastectomy. However, their expectations of surgery are often not met, and dissatisfaction with outcome and ongoing psychosocial concerns and distress are c...

    Authors: Diana Harcourt, Nicole Paraskeva, Paul White, Jane Powell and Alex Clarke

    Citation: BMC Medical Informatics and Decision Making 2017 17:143

    Content type: Study protocol

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  44. Mortality in end stage renal disease (ESRD) is higher than many malignancies. There is no data about the optimal way to present information about projected survival to patients with ESRD. In other areas, graph...

    Authors: Frances Dowen, Karishma Sidhu, Elizabeth Broadbent and Helen Pilmore

    Citation: BMC Medical Informatics and Decision Making 2017 17:137

    Content type: Research article

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  45. Expert opinion is often sought to complement available information needed to inform model-based economic evaluations in health technology assessments. In this context, we define expert elicitation as the proce...

    Authors: Bogdan Grigore, Jaime Peters, Christopher Hyde and Ken Stein

    Citation: BMC Medical Informatics and Decision Making 2017 17:131

    Content type: Research article

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  46. There is increasing recognition of the delicate balance between the modest benefits of palliative chemotherapy and the burden of treatment. Decision aids (DAs) can potentially help patients with advanced cance...

    Authors: Linda J. M. Oostendorp, Petronella B. Ottevanger, A. Rogier T. Donders, Agnes J. van de Wouw, Ivonne J. H. Schoenaker, Tineke J. Smilde, Winette T. A. van der Graaf and Peep F. M. Stalmeier

    Citation: BMC Medical Informatics and Decision Making 2017 17:130

    Content type: Research article

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  47. Hand hygiene is one of the most effective attempts to control nosocomial infections, and it is an important measure to avoid the transmission of pathogens. However, the compliance of healthcare workers (HCWs) ...

    Authors: Aslı Suner, Ozlem Ege Oruc, Cagri Buke, Hacer Deniz Ozkaya and Gul Kitapcioglu

    Citation: BMC Medical Informatics and Decision Making 2017 17:129

    Content type: Research article

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  48. Despite the emergence of genomics-based risk prediction tools in oncology, there is not yet an established framework for communication of test results to cancer patients to support shared decision-making. We r...

    Authors: James Abe, Jennifer M. Lobo, Daniel M. Trifiletti and Timothy N. Showalter

    Citation: BMC Medical Informatics and Decision Making 2017 17:128

    Content type: Research article

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