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Clinical decision-making, knowledge support systems, and theory

Section edited by Paul Taylor

This section aims to publish studies on the development, implementation and evaluation of clinical decision support systems. The section also accepts articles on the theoretical support of clinical decision-making (including shared-decision making), decision analysis, and decision aids.

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  1. Evidenced-based practice is a key component of quality care. This study aims to explore users’ expectations concerning paediatric local clinical practice guidelines.

    Authors: Joanna Dagard, Nadia Mazille-Orfanos, Nawras Georgi, Intissar Dechicha, Guy Carrault, Patrick Pladys and Alain Beuchée

    Citation: BMC Medical Informatics and Decision Making 2021 21:269

    Content type: Research article

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    The Correction to this article has been published in BMC Medical Informatics and Decision Making 2021 21:277

  2. Hospitalized people with unhealthy substance use should be referred to treatment. Although inpatient referral resources are often available, clinicians report that outpatient referral networks are not well-est...

    Authors: Kelli Thoele, Mengmeng Yu, Mandeep Dhillon, Robert Skipworth Comer, Hannah L. Maxey, Robin Newhouse and Ukamaka M. Oruche

    Citation: BMC Medical Informatics and Decision Making 2021 21:260

    Content type: Software

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  3. The International Consortium for Health Outcomes Measurement (ICHOM) develops condition-specific Standard Sets of outcomes to be measured in clinical practice for value-based healthcare evaluation. Standard Se...

    Authors: Caroline B. Terwee, Marloes Zuidgeest, Harald E. Vonkeman, David Cella, Lotte Haverman and Leo D. Roorda

    Citation: BMC Medical Informatics and Decision Making 2021 21:259

    Content type: Research article

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  4. Rhinosinusitis is an inflammation of the sinonasal cavity which affects roughly one in seven people per year. Acute rhinosinusitis (ARS) is mostly, apart from allergic etiology, caused by a viral infection and...

    Authors: L. Hart, A. Polášková and P. Schalek

    Citation: BMC Medical Informatics and Decision Making 2021 21:239

    Content type: Software

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  5. Home blood pressure measurements have equal or even greater predictive value than clinic blood pressure measurements regarding cardiovascular outcomes. With advances in home blood pressure monitors, we face an...

    Authors: Pete Wegier, Jeffery L. Belden, Shannon M. Canfield, Victoria A. Shaffer, Sonal J. Patil, Michael L. LeFevre, K. D. Valentine, Mihail Popescu, Linsey M. Steege, Akshay Jain and Richelle J. Koopman

    Citation: BMC Medical Informatics and Decision Making 2021 21:235

    Content type: Research article

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  6. The coronavirus disease (COVID-19), a pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown its destructiveness with more than one million confirmed cases and dozens of tho...

    Authors: Hetong Ma, Liu Shen, Haixia Sun, Zidu Xu, Li Hou, Sizhu Wu, An Fang, Jiao Li and Qing Qian

    Citation: BMC Medical Informatics and Decision Making 2021 21:231

    Content type: Database

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  7. Achilles tendon ruptures are common injuries in an otherwise healthy, active population. Several treatment options exist, with both surgical and non-surgical options. Each treatment option has a unique set of ...

    Authors: Brad Meulenkamp, Julia Brillinger, Dean Fergusson, Dawn Stacey and Ian D. Graham

    Citation: BMC Medical Informatics and Decision Making 2021 21:225

    Content type: Study protocol

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  8. Low back pain is a leading cause of disability worldwide. Health literacy has been associated with pain intensity and pain control. However, there is a paucity of evidence regarding this association. In the fi...

    Authors: Ye King Clarence See, Helen Elizabeth Smith, Lorainne Tudor Car, Joanne Protheroe, Wei Cong Wong and Bernadette Bartlam

    Citation: BMC Medical Informatics and Decision Making 2021 21:215

    Content type: Research article

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  9. In oncology, decision-making in individual situations is often very complex. To deal with such complexity, people tend to reduce it by relying on their initial intuition. The downside of this intuitive, subjec...

    Authors: Fabio Dennstädt, Theresa Treffers, Thomas Iseli, Cédric Panje and Paul Martin Putora

    Citation: BMC Medical Informatics and Decision Making 2021 21:212

    Content type: Review

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  10. In Chile, a patient needing a specialty consultation or surgery has to first be referred by a general practitioner, then placed on a waiting list. The Explicit Health Guarantees (GES in Spanish) ensures, by la...

    Authors: Fabián Villena, Jorge Pérez, René Lagos and Jocelyn Dunstan

    Citation: BMC Medical Informatics and Decision Making 2021 21:208

    Content type: Research article

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    The Correction to this article has been published in BMC Medical Informatics and Decision Making 2021 21:220

  11. Tools for shared decision-making (e.g. decision aids) are intended to support health care professionals and patients engaged in clinical encounters involving shared decision-making. However, decision aids are ...

    Authors: Anja Fog Heen, Per Olav Vandvik, Linn Brandt, Frankie Achille, Gordon Henry Guyatt, Elie A. Akl, Shaun Treewek and Thomas Agoritsas

    Citation: BMC Medical Informatics and Decision Making 2021 21:202

    Content type: Research article

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  12. Rational drug use requires that patients receive and take medication appropriately. Though the process of diagnosis and pharmaceutical care is complex, World Health Organization (WHO)/international network for...

    Authors: Teklehaimanot Fentie Wendie, Abdulmejid Ahmed and Solomon Ahmed Mohammed

    Citation: BMC Medical Informatics and Decision Making 2021 21:197

    Content type: Research article

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  13. Cardiovascular disease is the leading cause of death in many countries. Physicians often diagnose cardiovascular disease based on current clinical tests and previous experience of diagnosing patients with simi...

    Authors: Armin Yazdani, Kasturi Dewi Varathan, Yin Kia Chiam, Asad Waqar Malik and Wan Azman Wan Ahmad

    Citation: BMC Medical Informatics and Decision Making 2021 21:194

    Content type: Research article

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  14. Women with pathogenic BRCA1 and BRCA2 mutations possess a high risk of developing breast and ovarian cancer. They face difficult choices when considering preventive options. This study presents the development pr...

    Authors: Sibylle Kautz-Freimuth, Marcus Redaèlli, Kerstin Rhiem, Andrea Vodermaier, Lisa Krassuski, Kathrin Nicolai, Miriam Schnepper, Violetta Kuboth, Julia Dick, Vera Vennedey, Regina Wiedemann, Rita Schmutzler and Stephanie Stock

    Citation: BMC Medical Informatics and Decision Making 2021 21:180

    Content type: Research article

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  15. Different endometrial patterns have an important effect on the relationship between endometrial thickness (EMT) and clinical pregnancy rate. There is a significant difference in age, selection of cycle protoco...

    Authors: ShuJie Liao, Renjie Wang, Cheng Hu, Wulin Pan, Wei Pan, Dongyang Yu and Lei Jin

    Citation: BMC Medical Informatics and Decision Making 2021 21:176

    Content type: Research article

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  16. The promotion of early diagnosis is undoubtedly effective in reducing the burden of disease. Contrast-enhanced ultrasound (CEUS) is a diagnostic technology for liver cancer, but its implementation faces some c...

    Authors: Qingwen Deng, Yuhang Zheng, Junhong Lu, Zhichao Zeng and Wenbin Liu

    Citation: BMC Medical Informatics and Decision Making 2021 21:173

    Content type: Research article

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  17. Interventional studies are the fundamental method for obtaining answers to clinical questions. However, these studies are sometimes difficult to conduct because of insufficient financial or human resources or ...

    Authors: Yumi Wakabayashi, Masamitsu Eitoku and Narufumi Suganuma

    Citation: BMC Medical Informatics and Decision Making 2021 21:167

    Content type: Research article

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  18. Several epidemiological and cohort studies suggest that regular low-dose aspirin use independently reduces the long-term incidence and risk of colorectal cancer deaths by approximately 20%. However, there are ...

    Authors: Lenira Semedo, Kate J. Lifford, Adrian Edwards, Kathy Seddon, Kate Brain, Stephanie Smits and Sunil Dolwani

    Citation: BMC Medical Informatics and Decision Making 2021 21:165

    Content type: Research article

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  19. Robust identification of surrogate endpoints can help accelerate the development of pharmacotherapies for diseases traditionally evaluated using true endpoints associated with prolonged follow-up. The meta-ana...

    Authors: Milan Geybels, Benjamin Ole Wolthers, Frederik Flindt Kreiner, Søren Rasmussen and Robert Bauer

    Citation: BMC Medical Informatics and Decision Making 2021 21:164

    Content type: Technical advance

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  20. Current management of children with minor head trauma (MHT) and intracranial injuries is not evidence-based and may place some children at risk of harm. Evidence-based electronic clinical decision support (CDS...

    Authors: Jacob K. Greenberg, Ayodamola Otun, Azzah Nasraddin, Ross C. Brownson, Nathan Kuppermann, David D. Limbrick, Po-Yin Yen and Randi E. Foraker

    Citation: BMC Medical Informatics and Decision Making 2021 21:161

    Content type: Research article

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  21. Malaria is a major cause of death in children under five years old in low- and middle-income countries such as Malawi. Accurate diagnosis and management of malaria can help reduce the global burden of childhoo...

    Authors: Sanya B. Taneja, Gerald P. Douglas, Gregory F. Cooper, Marian G. Michaels, Marek J. Druzdzel and Shyam Visweswaran

    Citation: BMC Medical Informatics and Decision Making 2021 21:158

    Content type: Research article

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  22. While many studies have tested the impact of a decision aid (DA) compared to not receiving any DA, far fewer have tested how different types of DAs affect key outcomes such as treatment choice, patient–provide...

    Authors: Angela Fagerlin, Margaret Holmes-Rovner, Timothy P. Hofer, David Rovner, Stewart C. Alexander, Sara J. Knight, Bruce S. Ling, James A.Tulsky, John T. Wei, Khaled Hafez, Valerie C. Kahn, Daniel Connochie, Jeffery Gingrich and Peter A. Ubel

    Citation: BMC Medical Informatics and Decision Making 2021 21:154

    Content type: Research article

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  23. Despite the proven value of multicriteria decision analysis in the health field, there is a lack of studies focused on prioritising victims in the Emergency Medical Service, EMS. With this, and knowing that th...

    Authors: Talita D. C. Frazão, Ana F. A. dos Santos, Deyse G. G. Camilo, João Florêncio da Costa Júnior and Ricardo P. de Souza

    Citation: BMC Medical Informatics and Decision Making 2021 21:151

    Content type: Research article

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  24. Network meta-analysis (NMA) has been widely used in the field of medicine and health, but the research topics and development trends are still unclear. This study aimed to identify the cooperation of countries...

    Authors: Jiyuan Shi, Ya Gao, Liu Ming, Kelu Yang, Yue Sun, Ji Chen, Shuzhen Shi, Jie Geng, Lun Li, Jiarui Wu and Jinhui Tian

    Citation: BMC Medical Informatics and Decision Making 2021 21:144

    Content type: Research article

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  25. Healthcare providers need training to implement shared decision making (SDM). In Norway, we developed “Ready for SDM”, a comprehensive SDM curriculum tailored to various healthcare providers, settings, and com...

    Authors: Simone Kienlin, Marie-Eve Poitras, Dawn Stacey, Kari Nytrøen and Jürgen Kasper

    Citation: BMC Medical Informatics and Decision Making 2021 21:140

    Content type: Research article

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  26. Inguinal hernia repair, gallbladder removal, and knee- and hip replacements are the most commonly performed surgical procedures, but all are subject to practice variation and variable patient-reported outcomes...

    Authors: Floris M. Thunnissen, Bernhard W. Schreurs, Carmen S. S. Latenstein, Marjan J. Meinders, Eddy M. Adang, Glyn Elwyn, Doeke Boersma, Bas Bosmans, Koop Bosscha, Bastiaan L. Ginsel, Eric J. Hazebroek, Jeroen J. Nieuwenhuis, Maarten Staarink, Dries Verhallen, Marc L. Wagener, Femke Atsma…

    Citation: BMC Medical Informatics and Decision Making 2021 21:110

    Content type: Study protocol

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  27. Strabismus is a complex disease that has various treatment approaches each with its own advantages and drawbacks. In this context, shared decisions making (SDM) is a communication process with the provider sha...

    Authors: Ala Paduca, Oleg Arnaut, Eugeniu Beschieru, Per Olof Lundmark and Jan Richard Bruenech

    Citation: BMC Medical Informatics and Decision Making 2021 21:109

    Content type: Research article

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  28. In the recent decades, the use of computerized decision support software (CDSS)-integrated telephone triage (TT) has become an important tool for managing rising healthcare demands and overcrowding in the emer...

    Authors: Farah Islam, Marc Sabbe, Pieter Heeren and Koen Milisen

    Citation: BMC Medical Informatics and Decision Making 2021 21:107

    Content type: Research article

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  29. A central goal among researchers and policy makers seeking to implement clinical interventions is to identify key facilitators and barriers that contribute to implementation success. Despite calls from a numbe...

    Authors: Kristin M. Kostick, Meredith Trejo, Arvind Bhimaraj, Andrew Civitello, Jonathan Grinstein, Douglas Horstmanshof, Ulrich P. Jorde, Matthias Loebe, Mandeep R. Mehra, Nasir Z. Sulemanjee, Vinay Thohan, Barry H. Trachtenberg, Nir Uriel, Robert J. Volk, Jerry D. Estep and J. S. Blumenthal-Barby

    Citation: BMC Medical Informatics and Decision Making 2021 21:106

    Content type: Research article

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  30. Diabetes Mellitus (DM) has become the third chronic non-communicable disease that hits patients after tumors, cardiovascular and cerebrovascular diseases, and has become one of the major public health problems...

    Authors: Xuchun Wang, Mengmeng Zhai, Zeping Ren, Hao Ren, Meichen Li, Dichen Quan, Limin Chen and Lixia Qiu

    Citation: BMC Medical Informatics and Decision Making 2021 21:105

    Content type: Research article

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  31. Patients with complex health care needs may suffer adverse outcomes from fragmented and delayed care, reducing well-being and increasing health care costs. Health reform efforts, especially those in primary ca...

    Authors: David A. Dorr, Rachel L. Ross, Deborah Cohen, Devan Kansagara, Katrina Ramsey, Bhavaya Sachdeva and Jonathan P. Weiner

    Citation: BMC Medical Informatics and Decision Making 2021 21:104

    Content type: Research article

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  32. Clinical Decision Support Systems (CDSSs) for Prescribing are one of the innovations designed to improve physician practice performance and patient outcomes by reducing prescription errors. This study was ther...

    Authors: Sharare Taheri Moghadam, Farahnaz Sadoughi, Farnia Velayati, Seyed Jafar Ehsanzadeh and Shayan Poursharif

    Citation: BMC Medical Informatics and Decision Making 2021 21:98

    Content type: Research article

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  33. In the intensive care unit (ICU), delirium is a common, acute, confusional state associated with high risk for short- and long-term morbidity and mortality. Machine learning (ML) has promise to address researc...

    Authors: Caitlin E. Coombes, Kevin R. Coombes and Naleef Fareed

    Citation: BMC Medical Informatics and Decision Making 2021 21:97

    Content type: Research article

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  34. Over the last decades, the face of health care has changed dramatically, with big improvements in what is technically feasible. However, there are indicators that the current approach to evaluating evidence in...

    Authors: Wim van Biesen, Catherine Van Der Straeten, Sigrid Sterckx, Johan Steen, Lisa Diependaele and Johan Decruyenaere

    Citation: BMC Medical Informatics and Decision Making 2021 21:87

    Content type: Review

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  35. Colorectal cancer (CRC) is a common malignancy worldwide. Despite being the most common cancer in Singapore, CRC screening rate remains low due to knowledge deficits, social reasons such as inconvenience and a...

    Authors: Sok Wei Julia Yuen, Tsang Yew Tay, Ning Gao, Nian Qin Tho and Ngiap Chuan Tan

    Citation: BMC Medical Informatics and Decision Making 2021 21:86

    Content type: Research article

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  36. Cost control and usage regulation of medical materials (MMs) are the practical issues that the government pays close attention to. Although it is well established that there is great potential to mobilize doct...

    Authors: Guixian Tong, Qingqing Geng, Tong Xu, Debin Wang and Tongzhu Liu

    Citation: BMC Medical Informatics and Decision Making 2021 21:85

    Content type: Study protocol

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  37. Tumor necrosis factor α inhibitors (TNFi) is effective for rheumatoid arthritis (RA) patients who fail to conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs). Because of high cost, the dis...

    Authors: Juan Zhao, Wei Zhou, Yangfeng Wu, Ping Ji, Li Yang, Xiaoyan Yan and Zhuoli Zhang

    Citation: BMC Medical Informatics and Decision Making 2021 21:83

    Content type: Study protocol

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  38. Heart disease is the primary cause of morbidity and mortality in the world. It includes numerous problems and symptoms. The diagnosis of heart disease is difficult because there are too many factors to analyze...

    Authors: Qi Zhenya and Zuoru Zhang

    Citation: BMC Medical Informatics and Decision Making 2021 21:73

    Content type: Research article

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  39. Fatigue is a kind of non-specific symptom, which occurs widely in sub-health and various diseases. It is closely related to people's physical and mental health. Due to the lack of objective diagnostic criteria...

    Authors: Yulin Shi, Xiaojuan Hu, Ji Cui, Longtao Cui, Jingbin Huang, Xuxiang Ma, Tao Jiang, Xinghua Yao, Fang Lan, Jun Li, Zijuan Bi, Jiacai Li, Yu Wang, Hongyuan Fu, Jue Wang, Yanting Lin…

    Citation: BMC Medical Informatics and Decision Making 2021 21:72

    Content type: Research article

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  40. We know little about the best approaches to design training for healthcare professionals. We thus studied how user-centered and theory-based design contribute to the development of a distance learning program ...

    Authors: Moulikatou Adouni Lawani, Yves Turgeon, Luc Côté, France Légaré, Holly O. Witteman, Michèle Morin, Edeltraut Kroger, Philippe Voyer, Charo Rodriguez and Anik Giguere

    Citation: BMC Medical Informatics and Decision Making 2021 21:59

    Content type: Research article

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  41. Rheumatoid arthritis (RA) is an autoimmune disorder with systemic inflammation and may be induced by oxidative stress that affects an inflamed joint. Our objectives were to examine isotypes of autoantibodies a...

    Authors: Kai-Leun Tsai, Che-Chang Chang, Yu-Sheng Chang, Yi-Ying Lu, I-Jung Tsai, Jin-Hua Chen, Sheng-Hong Lin, Chih-Chun Tai, Yi-Fang Lin, Hui-Wen Chang, Ching-Yu Lin and Emily Chia-Yu Su

    Citation: BMC Medical Informatics and Decision Making 2021 21:49

    Content type: Research article

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  42. U.S. hospitals and dialysis centers are penalized for 30-day hospital readmissions of dialysis patients, despite little infrastructure to facilitate care transitions between these settings. We are developing a...

    Authors: Ann E. Vandenberg, Bernard G. Jaar, Kyle P. James, Janice Lea, Christopher O’Donnell, Tahsin Masud, Rich Mutell and Laura C. Plantinga

    Citation: BMC Medical Informatics and Decision Making 2021 21:47

    Content type: Research article

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  43. Researchers and policy makers have long suspected that people have differing, and potentially nefarious, motivations for participating in stated-preference studies such as discrete-choice experiments (DCE). Wh...

    Authors: Ilene L. Hollin, Ellen Janssen, Marcella A. Kelley and John F. P. Bridges

    Citation: BMC Medical Informatics and Decision Making 2021 21:44

    Content type: Research article

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  44. Quantitative data reports are widely produced to inform health policy decisions. Policymakers are expected to critically assess provided information in order to incorporate the best available evidence into the...

    Authors: Pamela Wronski, Michel Wensing, Sucheta Ghosh, Lukas Gärttner, Wolfgang Müller and Jan Koetsenruijter

    Citation: BMC Medical Informatics and Decision Making 2021 21:32

    Content type: Research article

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  45. Informed consent is required for participation in clinical trials, however trials involving adults who lack capacity to consent require different enrolment processes. A family member usually acts as a proxy to...

    Authors: Victoria Shepherd, Fiona Wood, Richard Griffith, Mark Sheehan and Kerenza Hood

    Citation: BMC Medical Informatics and Decision Making 2021 21:30

    Content type: Technical advance

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  46. Studies have revealed inappropriate laboratory testing as a source of waste. This review aimed at evaluating the effects and features of CDSSs on physicians' appropriate laboratory test ordering in inpatient h...

    Authors: Sahar Zare, Zahra Meidani, Mohammad Shirdeli and Ehsan Nabovati

    Citation: BMC Medical Informatics and Decision Making 2021 21:20

    Content type: Research article

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