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Table 2 Quantity of information of likelihood distributions for decisions about LST as measured by its entropy H(X) (mean ± standard deviation for multiple samples obtained by bootstrapping)

From: Contribution of information about acute and geriatric characteristics to decisions about life-sustaining treatment for old patients in intensive care

 

Hmax

Withholding decision

Withdrawing decision

VIP1

VIP2

VIP1

VIP2

Age

3.0

2.98 ± 0.003 (1.04, 1.02–1.06)

2.97 ± 0.004 (1.06, 1.04–1.08)

2.99 ± 0.005 (1.03, 1.0–1.05)

2.98 ± 0.009 (0.99, 0.82–1.02)

Gender (female vs male)

1.0

1.0 ± 0.0004 (0.98, 0.84–1.13)

1.0 ± 0.0004 (1.02,0.88–1.18)

0.99 ± 0.002 (0.79, 0.66–0.95)

1.0 ± 0.001 (0.99, 0.82–1.2)

Frailty (CFS)

3.0

2.91 ± 0.009 (1.22, 1.17–1.27)

2.95 ± 0.006 (1.15, 1.1–1.20)

2.96 ± 0.01 (1.08, 1.03–1.14)

2.99 ± 0.003 (1.0, 0.95–1.05)

SOFA

3.0

2.97 ± 0.005 (1.03, 1.01–1.05)

2.94 ± 0.007 (1.07, 1.05–1.09)

2.78 ± 0.02 (1.12, 1.10–1.15)

2.80 ± 0.02 (1.14, 1.12–1.17)

Other geriatric features:

 

Not available

 

Not available

 

 Co-morbidities (number)

3.0

 

2.98 ± 0.003 (1.02, 0.99–1.06)

 

2.97 ± 0.01 (0.98, 0.93–1.02)

 Functional impairment (Katz index)

2.8

 

2.78 ± 0.004 (1.01, 0.96–1.07)

 

2.79 ± 0.007(1.05, 0.97–1.14)

 Residence (home - baseline)*

2.0

 

1.99 ± 0.004

 

1.97 ± 0.02

   Home with caregiver

  

(0.8, 0.61–1.03)

 

(0.68, 0.46–0.99)

   Nursing home/hospital

  

(1.05, 0.83–1.32)

 

(1.15, 0.84–1.56)

  1. Note that the maximum entropy Hmax varies according to the number of bins for each variable. Odds ratios (per 1-point increase) and 95% confidence intervals from logistic regression are depicted in brackets to show the influence of specific variables in these decisions
  2. *Note that H(X) describes the distribution of probabilities for all residence categories, whereas the odds ratios are determined for comparisons between two specific types of residence