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Fig. 1 | BMC Medical Informatics and Decision Making

Fig. 1

From: Harmonising electronic health records for reproducible research: challenges, solutions and recommendations from a UK-wide COVID-19 research collaboration

Fig. 1

A simplified example of the four-layer data preparation process used to harmonise data within SAIL with data for England (within the NHS Digital TRE for England). Layer 1 consists of raw data sources in SAIL (e.g., primary care and secondary care data sources). Layer 2 includes Research Ready Data Assets (RRDAs) and generated curated version of raw data sources. Examples of RRDAs are the COVID-19 C20 cohort, combined mortality data for COVID-19 C20 cohort [47] and RRDA version of dispensing data [45]. In Layer 3, phenotypes related data are generated using Layer 2 data and phenotype code-lists. Many phenotype code-lists in the HDR UK Phenotype Library [12] have already been imported into SAIL (only a subset of phenotypes has been displayed for illustrative purposes). Finally, in Layer 4 fully harmonised project-specific data tables are derived from Layer 2 and 3 data

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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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