Fig. 3
From: In silico clinical trials for relapsing-remitting multiple sclerosis with MS TreatSim
Distribution of disease and immune system characteristics for Populations 1 and 2. Each population consists of 200 DPs. A Histogram showing the total number of relapses over 5 years, divided between 1 or 2 relapses, or three or more. B Mean total B cells over 5 years. Distributions and medians of the mean B cell number were both found to be significantly different between Populations 1 and 2 (p < 0.001). C Mean total CD4+ T cells over 5 years. Distributions and medians of the mean CD4 + T cells were both found to be significantly different between Populations 1 and 2 (p < 0.001). D Mean IFN-γ over 5 years. Distributions and medians of the mean IFN-γ concentration were both found to be significantly different between Populations 1 and 2 (p < 0.001). * = distributions and medians difference, p < 0.001