Table 2 Predicted situations for hypothetical cases

Medicine that should not be used concurrently

“ACETYL-SALICYLIC ACID” and “WARFARIN” present in drugs “ASPIRIN 500 mg” and “WARFARIN 2.5 mg” in the same prescription

Prescription for patients who have an active daytime routine

Patient who wakes up at 7am, work from 8am to 12 pm and from 1 to 6 pm. Sleeps at 10 pm

Prescription for patients who have an active night routine

Patient who works from 10 pm to 6am and sleeps from 7:30am to 2:30 pm

Medicines that require a minimum interval between doses

Use of “DIGOXIN” and “MYLANTA PLUS®” which have interaction between active principles “DIGOXIN” and “ALUMINUM HYDROXIDE” requiring an interval between doses

Prescription for a patient who has a health condition in which a drug is contraindicated

Patient with severe liver disease (cirrhosis) with prescription of “ATORVASTATIN CALCIUM” which is contraindicated drug for this situation

Overdose prescription for a particular drug

2-years-old child weighing 13 kg with a prescription of the “AZITROMYCIN” with a dose higher than the maximum dosage allowed for the child’s weight

Prescription of medications that need interaction with food

Prescription of “OMEPRAZOLE” which is indicated to be used on an empty stomach

Prescription for patients in which sleep disruption should be avoided

6-years-old child who needs antibiotics every 8 h

Medicine with indication not to be used, but by clinical decision opted for the risk

“CARBAMAZEPINE” for a pregnant woman with 12 weeks of gestation, to avoid epilepsy crises

Medicines that need specific guidelines for use

Use of “ALENDRONATE SODIUM” and “LEVOTHYROXINE”