Fig. 2

PharmaCheck screenshots. Top screenshot: This example presents the results produced by a PharmaCheck alert when prescribing certain anticoagulants (apixaban—Eliquis®, rivaroxaban—Xarelto®) in the presence of a creatinine clearance below 30 mL/min. The first columns show patient name, age, episode-of-care number (hidden in screenshot) The following columns show inpatient unit (“Unité de soins”), and current medical order (“OM actuel”) related to the anticoagulant. Then the creatinine clearance is calculated using the Cockcroft and Gault formula (“Clairance CG”), taking into account the patient’s adjusted weight (“Clairance CG selon”). PharmaCheck enables patient’s adjusted weight calculation using mathematical operations that consider sex, creatinine values, weight, and height. Similarly, further mathematical operations are performed on available estimated renal function values (“Delta eGFR”). These operations calculate the progression of renal function (14% and 116% increases, respectively) between the last two eGFR measurements. Bottom screenshot: This example presents the results produced by a PharmaCheck alert when prescribing drugs lowering seizure threshold (“Traitements”) in patients with a history of epilepsy characterized by the French world "épilepsie" in patient notes (“Problème”)