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Table 1 Baseline characteristics of the NR study population (n = 854)

From: Machine learning to predict no reflow and in-hospital mortality in patients with ST-segment elevation myocardial infarction that underwent primary percutaneous coronary intervention

Variable Normal blood flow (n = 755) NR (n = 99) p-value
Age (years) 60.34 (13.27) 62.79 (13.88) 0.086
Male (n (%)) 628 (83.2) 74 (74.7) 0.039
Hypertension (n (%)) 345 (45.7) 38 (38.4) 0.169
Diabetes (n (%)) 124 (16.4) 12 (12.1) 0.271
Smoke (n (%)) 377 (49.9) 34 (34.3) 0.004
Angina pectoris (n (%)) 41 (5.4) 7 (7.1) 0.505
Previous PCI (n (%)) 19 (2.5) 5 (5.1) 0.267
Anterior wall MI (n(%)) 391 (51.8) 48 (48.5) 0.536
Cardiac troponin I (normalized) 0.47 (0.33) 0.67 (0.31)  < 0.001
creatine kinase-MB (normalized) 0.13 (0.13) 0.22 (0.17)  < 0.001
hs-CRP (normalized) 0.34 (0.33) 0.50 (0.39)  < 0.001
Hemoglobin (g/L) 137.65 (19.28) 133.90 (19.60) 0.07
WBC count (109/L) 11.50 (3.94) 12.40 (3.78) 0.033
Creatinine (μmol/L) 89.68 (43.15) 99.38 (45.22) 0.037
Uric acid (μmol/L) 385.33 (118.53) 407.30 (135.37) 0.089
Albumin (g/L) 38.72 (4.37) 38.43 (4.91) 0.544
Glucose (mmol/L) 7.31 (3.44) 7.52 (2.84) 0.577
LDL-C (mmol/L) 3.28 (1.05) 3.12 (0.97) 0.156
HDL-C (mmol/L) 1.20 (0.44) 1.15 (0.32) 0.351
Triglyceride (mmol/L) 1.65 (1.13) 1.60 (1.25) 0.734
Total cholesterol (mmol/L) 5.01 (1.24) 4.89 (1.26) 0.347
Fibrinogen (g/L) 3.65 (1.08) 3.63 (1.24) 0.862
Shock (%) 13 (1.7) 7 (7.1) 0.003
Malignant arrhythmia (n (%)) 90 (11.9) 18 (18.2) 0.078
Killip class (n (%))
 I 610 (80.8) 64 (64.6)  < 0.001
 II 83 (11.0) 15 (15.2) 0.222
 III 15 (2.0) 3 (3.0) 0.758
 IV 47 (6.2) 17 (17.2)  < 0.001
LVEF (%) 57.97 (9.15) 54.30 (10.16)  < 0.001
Total ischemia time (h) 4.85 (3.51) 6.29 (5.61)  < 0.001
SO-to-FMC (min) 157.21 (166.20) 262.06 (290.03)  < 0.001
Door-to balloon (min) 85.68 (49.34) 88.53 (54.05) 0.594
Baseline TIMI flow
 0 581 (77.0) 90 (90.9) 0.001
 1 38 (5.0) 5 (5.1) 1.0
 2 77 (10.2) 1 (1.0) 0.003
 3 59 (7.8) 3 (3.0) 0.085
Criminal blood vessels (n (%))
 LAD 431 (57.3) 49 (49.5) 0.140
 LCX 56(7.4) 8 (8.1) 0.814
 RCA 263 (34.8) 41 (41.4) 0.199
 LM 5 (0.7) 1 (1.0) 0.524
Double or multiple lesions (n (%)) 501 (66.4) 78 (78.8) 0.013
Post dilatation (n (%)) 446 (59.1) 56 (56.6) 0.634
Thrombus aspiration (n (%)) 84 (11.1) 29 (29.3)  < 0.001
Stent diameter (mm) 3.14 (0.43) 3.14 (0.40) 0.895
Stent length (mm) 33.94 (17.25) 41.57 (18.78)  < 0.001
  1. hs-CRP high-sensitivity C-reactive protein, HDL-C high-density lipoprotein cholesterol, LVEF left ventricular ejection fraction, LAD left anterior descending coronary artery, LCX left coronary circumflexus artery, LDL-C low-density lipoprotein cholesterol, LM left main coronary artery, MI myocardial infarction, PCI percutaneous transluminal coronary intervention, RCA right coronary artery, SO-to-FMC symptom-onset to-first medical contact, TIMI thrombolysis and thrombin inhibition in myocardial infarction