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Fig. 2 | BMC Medical Informatics and Decision Making

Fig. 2

From: Discovery of genes positively modulating treatment effect using potential outcome framework and Bayesian update

Fig. 2

Discovery of positive modulator genes by C-search in the cBioPortal breast cancer dataset. Nine causal genes are discovered, and patients with causal genes are assigned to the causal gene group. Patients without casual genes are assigned to the other gene group. All Kaplan − Meier survival curves are adjusted with propensity score matching [39]; 95% confidence intervals are depicted, and p-values are noted. a Kaplan − Meier survival curves of the causal gene group and the other gene group. b Treated and untreated patients are compared in the causal gene group. c Treated and untreated patients are compared for the other gene group. d The causal gene and other gene group are compared between treated patients. e The causal gene and other gene group are compared between the untreated patients. f Survival curve following the optimal policy and the other policy is shown

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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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