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Fig. 6 | BMC Medical Informatics and Decision Making

Fig. 6

From: Expediting knowledge acquisition by a web framework for Knowledge Graph Exploration and Visualization (KGEV): case studies on COVID-19 and Human Phenotype Ontology

Fig. 6

Shortest path search example. The search represents paths with a length of three edges between obesity and COVID-19 through nodes under the UMLS semantic group of “Genes & Molecular Sequences”. Direct paths are excluded. The edges represent disease-gene relationships from DisGeNET and gene-phenotype relationships from HPO to obtain obesity-associated genes, and gene–gene relationships from STRING (interaction score >  = 700, representing high confidence interactions) and CORD-19 (at least 7 supporting texts). The search results represent some of the pathways through with obesity may be associated with COVID-19 risk. The graph in the figure represents a subset of the results; The full results can be viewed by following the search settings in the tutorial section of the KGEV website (http://covid19nlp.wglab.org/tutorial)

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