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Table 1 Characteristics of included studies

From: Telemedicine application in patients with chronic disease: a systematic review and meta-analysis

Author, year

Participants with disease

Telemedicine inventions

Intervention providers

Outcome index

Experiment duration

Conclusion

Han Yun et al. [30]

(Diabetes)

(1) Experiment sample size:46

(2) Control sample size:45

Age:25–75

Telemedicine inventions: web-based consultation

Endocrinologist; nurse; nutritionist; exercise therapist; doctor

HbA1c

FBG

PBG

3/6/12 months

FBG was reduced

Kun et al. [40]

(Diabetes)

(1) Experiment sample size: 97

Age: 52.6士9.1

(2) Control sample size:89

Age: 54.7土10.3

Telemedicine inventions: Telemonitoring

Nurse

Doctor

HbA1C

FBG

HDL-C

LDL-C

3/6 months

FBG, HbA1c were improved

Lee et al. [28]

(Diabetes)

(1) Experiment sample size:120

Age: 56.1 ± 9.2

(2) Control sample size:120

Age: 70.9 ± 6.8

Telemedicine inventions: Telemonitoring

Doctor

Researcher

Clinician

HbA1C

FBG

BP

LDL

Total cholesterol

1/3/6/12 months

SBP and total cholesterol were statistically significant

Shea et al. [38]

(Diabetes)

(1) Experiment sample size:700

Age: 70.8 ± 6.5

(2) Control sample size:717

Age: 70.9 ± 6.8

Telemedicine inventions: Remote consultation

Nurse case manages; physician

HbA1c

LDL

BP

12 months

HbA1c, BP and LDL were improved

Shea et al. [39]

(Diabetes)

(1) Experiment sample size:729

Age: 70.8 ± 6.5

(2) Control sample size:716

Age: 70.9 ± 6.8

Telemedicine inventions: remote consultation

Nurse case manages; physician

HbA1c

LDL

BP

12/24/36/48/60 months

HbA1c, BP and LDL levels were improved

Sood et al. [31]

(Diabetes)

(1) Experiment sample size:199

Age: 61.6 ± 9.4

(2)Control sample size:83

Age: 61.1 ± 10.0

Telemedicine inventions: Remote consultation

A team of a diabetes specialist (endocrinologist) and a nurse practitioner

HbA1c

BP

LDL

HDL

18 months

HbA1c was no statistically significant

Fountoulakis et al. [26]

(Diabetes)

(1) Experiment sample size:70

Age: 55.2 ± 16.1

(2) Control sample size:35

Age: 55.4 ± 19.2

Telemedicine inventions: telemonitoring

Outpatient Department Endocrinologists

Doctor

HbA1c

BMI

Cost

3/6/6 months after discontinuation

Telemonitoring effective in rapidly reducing HbA1c

Lu et al. [35]

(Diabetes)

(1) Experiment sample size:60

Age:56.75 ± 12.05

(2) Control sample size:59

Age: 53.17 ± 11.44

Telemedicine inventions: Internet-based consultation

pharmacist

HbA1c

FBG

edication

6 months

HbA1c and FBG were no statistically significant

Yuli Hu et al. [34]

(Diabetes)

(1) Experiment sample size:72

Age:50.04 ± 5.76

(2) Control sample size:70

Age:52.21 ± 8.38

Telemedicine inventions: Internet-based consultation

Doctors

Nurses

HbA1c

Urinary albumin to creatinine ratio

Carotid plaque

 

The telemedicine system reduced rate of hypoglycemia and indexes of HbA1c

Jia et al. [32]

(Hypertension)

(1) Experiment sample size:81

Age: 70.2 ± 6.5

(2) Control sample size:81

Age: 69.2 ± 6.7

Telemedicine inventions: Internet-based consultation

Nurse

Doctor

BP

6 months

BP was improved

Margolis et al. [37]

(Hypertension)

(1) Experiment sample size:228

Age: 62.0 ± 11.7

(2) Control sample size:222

Age: 60.2 ± 12.2

Telemedicine inventions: telemonitoring

Pharmacists

Doctor

BP

6/12/18/54 months

BP was decreased after 12 months

McManus et al. [33]

(Hypertension)

(1)Experiment sample size:234

Age: 66.6 ± 8.8

(2) Control sample size:246

Age: 66.2 ± 8.8

Telemedicine inventions: Telemonitoring

Research team; Family doctor

BP

6/12 months

BP changed significantly after 6 months and 12 months

Richard et al.

(Hypertension)

(1) Experiment sample size:269

Age: 65.2 ± 10.3

(2) Control sample size:278

Age: 66.7 ± 10.2

Telemedicine inventions: telemonitoring

Healthcare practitioners

BP

6/12 months

The systolic blood pressure was improved after one year than usual care

Song et al. [29]

(Rheumatoid arthritis)

(1) Experiment sample size: 41

(2) Control sample size: 36

Age: 55.26 ± 10.84

Telemedicine inventions: telemonitoring

Nurses

Medication compliance

Disease activity

3/6 months

The intervention group had significantly higher medication adherence

Ferwerda et al. [27]

(Rheumatoid arthritis)

(1) Experiment sample size: 62

(2) Control sample size: 71

Age: 56.35 ± 10.00

Telemedicine inventions: internet-based consultation

Therapists

Beck depression inventory

Negative mood

Anxiety

Satisfaction

3/6/9/12 months

Patients with psychological distress have reduced

  1. HbA1c glycosylated hemoglobin; FBG fasting blood glucose; PBG postprandial blood glucose; FPG fasting plasma glucose; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol; BMI Body Mass Index; BP blood pressure; LDL low density lipoprotein; HbA1c glycosylated hemoglobin; HDL high density lipoprotein; SBP systolic blood pressure; DBP diastolic blood pressure