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Table 2 Significance test analysis of the indicators used to predict AD

From: Solving the class imbalance problem using ensemble algorithm: application of screening for aortic dissection

Variables

AD

N = 802

Non-AD

N = 52,411

\({\upchi }^{2}/\mathrm{t}\)

P value

1.1 MCV

91.84 ± 6.82

92.10 ± 7.17

− 1.04

0.161

1.2 MPV

8.93 ± 1.39

9.3 ± 1.58

− 7.59

 < 0.001

1.3 HGB

119.76 ± 21.57

119.95 ± 22.47

− 0.23

0.18

1.4 A/G

1.40 ± 0.36

1.49 ± 0.37

− 6.71

0.88

1.5 NEUT

7.16 ± 4.08

4.79 ± 3.47

19.12

 < 0.001

1.6 NEUT%

72.83 ± 10.79

65.30 ± 12.09

17.53

0.02

1.7 LYMPH%

16.94 ± 9.10

24.22 ± 10.44

− 19.64

0.01

1.8 LYMPH

1.36 ± 0.60

1.57 ± 2.03

− 2.92

0.22

2.1 TP

64.58 ± 7.06

65.43 ± 8.04

− 3.01

 < 0.001

2.2 AIB

37.08 ± 5.67

38.61 ± 6.26

− 6.9

0.04

2.3 GIOB

27.57 ± 5.19

26.94 ± 5.32

3.31

0.13

2.4 TB

16.19 ± 21.62

13.20 ± 26.81

3.13

0.07

2.5 DB

6.65 ± 11.52

5.39 ± 13.53

2.63

0.09

2.6 TBA

6.22 ± 13.32

7.55 ± 15.04

− 2.49

0.17

2.7 ALT

66.50 ± 296.27

32.47 ± 108.73

8.4

 < 0.001

2.8 AST

85.34 ± 510.27

36.33 ± 155.39

8.28

 < 0.001

2.9 UREA

7.37 ± 5.21

7.06 ± 5.21

1.66

0.29

2.10 CREA

136.87 ± 156.07

138.98 ± 213.75

− 0.28

0.08

2.11 UA

337.62 ± 128.66

349.58 ± 116.65

− 2.88

 < 0.001

2.12 HBA1C

2.25 ± 0.62

2.03 ± 0.73

8.39

0.05

2.13 CHO

4.33 ± 0.43

4.37 ± 0.55

− 2.19

0.81

2.14 HDL

1.12 ± 0.17

1.12 ± 0.17

− 0.28

0.71

2.15 LDL

2.60 ± 0.35

2.63 ± 0.46

− 1.98

0.51

2.16 LDH

322.03 ± 684.10

236.51 ± 283.48

8.19

 < 0.001

2.17 CK

538.04 ± 5272.64

162.57 ± 567.45

12.3

 < 0.001

2.18 CK-MB

35.93 ± 299.32

19.33 ± 33.08

9.48

 < 0.001

2.19 MYOG

72.69 ± 84.95

57.60 ± 59.02

7.13

 < 0.001

2.20 K + 

3.83 ± 0.56

3.97 ± 0.52

− 7.52

 < 0.001

2.21 Na + 

139.37 ± 4.28

140.71 ± 3.79

− 9.89

 < 0.001

2.22 Cl-

101.08 ± 4.95

102.59 ± 4.62

− 9.15

0.01

2.23 CO2CP

23.14 ± 3.21

23.20 ± 3.65

− 0.45

 < 0.001

2.24 AG

15.24 ± 3.68

14.95 ± 3.35

2.38

0.7

2.25 Ca + 

2.16 ± 0.16

2.21 ± 0.18

− 7.85

0.01

2.26 P + 

1.19 ± 0.39

1.19 ± 0.34

− 0.64

0.01

2.27 Mg + 

0.90 ± 0.13

0.89 ± 0.13

2.38

0.56

2.28 ESR

31.34 ± 28.57

37.87 ± 30.34

− 6.054

0.023

2.29 FT3

3.77 ± 0.90

3.95 ± 1.60

− 3.32

0.034

2.30 TSH

3.18 ± 7.86

3.52 ± 7.47

− 1.258

0.442

3.1 PT%

99.83 ± 18.59

106.62 ± 17.36

− 10.984

 < 0.001

3.2 INR

1.06 ± 0.39

1.01 ± 0.28

5.281

 < 0.001

3.3 APTT

37.66 ± 11.29

35.54 ± 9.68

6.14

 < 0.001

3.4 FIB

4.44 ± 1.81

3.77 ± 1.22

15.223

 < 0.001

3.5 D-Dimer

1.37 ± 1.94

0.97 ± 1.27

8.808

 < 0.001

3.6 PLGAg

252.01 ± 24.57

255.86 ± 27.68

− 3.914

 < 0.001

3.7 TT

18.92 ± 14.17

19.11 ± 12.91

− 0.398

0.078

3.8 PT

13.57 ± 4.39

13.02 ± 3.06

5.08

 < 0.001

3.9 AT-III

271.19 ± 17.23

271.18 ± 21.52

0.01

0.77

4.1 Chest pain

206(25.69)

9460(18.05)

30.985

 < 0.001

4.2 Stomach ache

66(8.23)

2996(5.72)

9.199

0.002

4.3 Heart palpitations

63(7.86)

6106(11.65)

11.099

0.001

4.4 Dizziness and headache

62(7.73)

7803(14.89)

32.127

 < 0.001

4.5Aortic valve area murmur

23(2.87)

377(0.72)

48.875

 < 0.001

4.6 Family history of hypertension

92(11.47)

4798(9.15)

5.081

0.024

4.7 Family history of aortic dissection

0(0.00)

2(0.00)

0.031

0.861

4.8 Chest trauma history

11(1.37)

206(0.39)

18.623

 < 0.001

4.9 Hypertension

530(66.08)

31,571(60.24)

11.285

0.001

4.10 Diabetes

88(10.97)

11,910(22.72)

62.467

 < 0.001

4.11 Family history of diabetes

8(1.00)

1480(2.82)

9.693

0.002

4.12 Sex

228(28.43)

22,417(42.77)

66.471

 < 0.001

4.13 Hypertension and duration

6.01 ± 6.47

6.10 ± 7.09

− 0.33

 < 0.001

4.14 Smoking and duration

10.22 ± 14.39

7.34 ± 13.88

5.831

 < 0.001

4.15 Stop smoking and duration

0.57 ± 2.64

0.78 ± 3.26

− 1.82

 < 0.001

4.16 Drinking and duration

6.62 ± 11.68

5.57 ± 11.10

2.652

 < 0.001

4.17 Stop drinking and duration

0.17 ± 1.12

0.24 ± 1.65

− 1.209

0.016

4.18 Systolic pressure

142.41 ± 26.71

136.86 ± 21.90

7.091

 < 0.001

4.19 Diastolic pressure

83.20 ± 16.59

80.46 ± 13.01

5.896

 < 0.001

4.20 Heart rate

81.74 ± 13.87

78.73 ± 14.20

5.967

0.31

4.21 Age

55.57 ± 12.90

62.56 ± 13.06

− 15.034

0.319

4.22 Smoking

0.66 ± 0.53

0.82 ± 0.51

− 9.114

 < 0.001

4.23 Drinking

0.81 ± 0.48

0.85 ± 0.44

− 2.426

 < 0.001

4.24 Diabetes and duration

0.85 ± 2.87

1.82 ± 3.83

− 7.113

 < 0.001

  1. The bold items were features selected by significance test
  2. The underlined items were features selected by logistic regression and not by significance test