|
# patients
|
5
|
9
|
2
|
2
|
|
Duration of trial (days), mean (SD)
|
22.60
|
22.11
|
22.50
|
22.00
|
|
(1.95)
|
(0.33)
|
(0.71)
|
(0.00)
|
|
Total # headache attacks
|
20
|
78
|
20
|
15
|
|
# attacks per patient, mean (SD)
|
4.00
|
8.67
|
10.00
|
7.50
|
|
(2.74)
|
(3.46)
|
(7.07)
|
(0.71)
|
|
Pain intensity of attacks, mean (SD)
|
2.00
|
1.76
|
1.50
|
2.27
|
|
(0.92)
|
(0.81)
|
(0.61)
|
(0.70)
|
|
Pct. of attacks w/ pain intensity
| | | | |
|
0 (no pain)
|
0.00%
|
0.00%
|
0.00%
|
0.00%
|
|
1 (mild pain)
|
30.00%
|
46.15%
|
55.00%
|
13.33%
|
|
2 (moderate pain)
|
50.00%
|
33.33%
|
40.00%
|
46.67%
|
|
3 (severe pain)
|
10.00%
|
19.23%
|
5.00%
|
40.00%
|
|
4 (very severe pain)
|
10.00%
|
1.28%
|
0.00%
|
0.00%
|
|
Duration (HH:mm), mean (SD)
|
08:27
|
05:59
|
00:22
|
00:50
|
| |
(09:39)
|
(05:42)
|
(00:15)
|
(00:20)
|
|
Pct. of unilateral attacks
|
45.00%
|
73.08%
|
100.00%
|
100.00%
|
|
# symptoms per attack, mean (SD)
|
4.40
|
2.29
|
0.65
|
2.73
|
| |
(2.41)
|
(2.10)
|
(0.67)
|
(1.03)
|
|
# triggers per attack, mean (SD)
|
0.75
|
0.83
|
0.35
|
0.33
|
| |
(0.79)
|
(0.90)
|
(0.49)
|
(0.49)
|
|
Pct. of attacks w/o symptom
|
0.00%
|
19.23%
|
45.00%
|
0.00%
|
|
Pct. of attacks w/o trigger
|
45.00%
|
43.59%
|
65.00%
|
66.67%
|
|
Pct. of attacks treated
|
95.00%
|
51.28%
|
70.00%
|
100.00%
|
|
Pct. of attacks treated successfully
|
75.00%
|
37.18%
|
70.00%
|
93.33%
|
|
Pct. of attacks w/ selected symptom:
| | | | |
|
Conjunctival injection
|
10.00%
|
0.00%
|
5.00%
|
26.67%
|
|
Lacrimation
|
15.00%
|
5.13%
|
0.00%
|
26.67%
|
|
Ptosis
|
0.00%
|
8.97%
|
0.00%
|
0.00%
|
|
Miosis
|
0.00%
|
6.41%
|
0.00%
|
0.00%
|
|
Eyelid oedema
|
5.00%
|
6.41%
|
10.00%
|
0.00%
|
|
Nasal congestion
|
20.00%
|
7.69%
|
0.00%
|
80.00%
|
|
Rhinorrhoea
|
20.00%
|
3.85%
|
0.00%
|
6.67%
|
|
Sweaty forehead and face
|
25.00%
|
1.28%
|
0.00%
|
0.00%
|
|
Pulsating pain
|
75.00%
|
34.62%
|
45.00%
|
53.33%
|
|
Movement sensitivity
|
40.00%
|
28.21%
|
0.00%
|
6.67%
|
|
Pain increment during routine physical activity
|
40.00%
|
25.64%
|
0.00%
|
6.67%
|
|
Restlessness or agitation
|
30.00%
|
21.79%
|
5.00%
|
60.00%
|
|
Photophobia
|
95.00%
|
24.36%
|
0.00%
|
6.67%
|
|
Phonophobia
|
35.00%
|
29.49%
|
0.00%
|
0.00%
|
|
Osmophobia
|
20.00%
|
2.56%
|
0.00%
|
0.00%
|
|
Nausea
|
10.00%
|
23.08%
|
0.00%
|
0.00%
|
|
Vomiting
|
0.00%
|
0.00%
|
0.00%
|
0.00%
|
