Fig. 3

Role of cbpManager in use case of a MTB. For the discussion of a patient in MTB, a molecular analysis of the tumor is performed and clinical information such as diagnosis and previous therapies are retrieved from the medical records (MR). A medical documentalist applies cbpManager to create data files suitable for the upload in cBioPortal. For this, molecular data should be prepared in a MAF format, while samples and clinical data are added via the cpbManager interface. Once imported in cBioPortal, molecular aberrations are automatically annotated and previous therapies are visualized. This facilitates the patient-specific selection of a therapy in MTB