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Table 1 Characteristics of patients with a minimum of 1, 3, and 5 years of follow up time

From: Adapted time-varying covariates Cox model for predicting future cirrhosis development performs well in a large hepatitis C cohort

  1-year minimum (n = 146,182) 3-year minimum (n = 110,559) 5-year minimum (n = 84,189) All (n = 182,772)
Age (years), mean (SD) 52.5 (8.28) 52.4 (8.08) 52.2 (7.75) 52.4 (8.32)
Male, n (%) 141,663 (96.9%) 107,012 (96.8%) 81,449 (96.7%) 177,270 (97.0%)
Race, n (%)     
Black 51,206 (35.0%) 40,445 (36.6%) 32,007 (38.0%) 63,017 (34.5%)
White 74,948 (51.3%) 56,817 (51.4%) 42,834 (50.9%) 93,240 (51.0%)
Hispanic 6646 (4.5%) 4906 (4.4%) 3639 (4.3%) 8414 (4.6%)
Other 2561 (1.8%) 1913 (1.7%) 1427 (1.7%) 3212 (1.8%)
Missing 10,821 (7.4%) 6478 (5.9%) 4282 (5.1%) 14,889 (8.1%)
BMI, mean (SD) 27.5 (5.24) 27.5 (5.23) 27.6 (5.23) 27.4 (5.24)
History of alcohol use disorder 73,961 (50.6%) 56,466 (51.1%) 43,473 (51.6%) 93,045 (50.9%)
History of substance use disorder 75,350 (51.5%) 58,339 (52.8%) 45,478 (54.0%) 94,167 (51.5%)
Diabetes mellitus 47,846 (32.7%) 37,977 (34.3%) 30,125 (35.8%) 57,889 (31.7%)
Human immunodeficiency virus 4085 (2.8%) 3373 (3.1%) 2738 (3.3%) 4863 (2.7%)
Received antiviral treatment*, n (%) 75,820 (51.9%) 61,435 (55.6%) 49,338 (58.6%) 95,630 (52.3%)
SVR, n (%) 69,475 (47.5%) 56,534 (51.1%) 45,629 (54.2%) 76,854 (42.0%)
Baseline laboratory values, mean (SD)     
APRI 0.648 (0.692) 0.609 (0.510) 0.585 (0.473) 0.668 (0.686)
Albumin (g/dL) 3.99 (0.447) 4.01 (0.437) 4.01 (0.430) 3.98 (0.461)
Alanine aminotransferase (U/L) 65.8 (53.6) 64.2 (52.0) 63.3 (50.7) 67.1 (55.9)
Aspartate aminotransferase (U/L) 51.5 (33.4) 49.7 (31.6) 48.6 (30.6) 52.5 (34.3)
Total bilirubin (mg/dL) 0.706 (0.407) 0.696 (0.373) 0.691 (0.369) 0.716 (0.472)
Blood urea nitrogen (mmol/L) 14.1 (7.15) 14.0 (6.84) 14.0 (6.61) 14.1 (7.44)
Chloride (mmol/L) 103 (3.57) 103 (3.52) 103 (3.51) 103 (3.60)
Creatinine (mg/dL) 1.04 (0.743) 1.04 (0.713) 1.04 (0.686) 1.05 (0.769)
Glucose (mg/dL) 115 (59.6) 115 (59.5) 115 (59.6) 115 (59.5)
Hemoglobin (g/dL) 14.9 (1.59) 15.0 (1.56) 15.0 (1.54) 14.9 (1.62)
INR 1.05 (0.282) 1.05 (0.287) 1.05 (0.278) 1.06 (0.282)
Platelet (1000/µL) 229 (72.5) 231 (71.3) 233 (70.7) 228 (73.7)
Potassium (mEq/dL) 4.23 (0.441) 4.23 (0.439) 4.23 (0.438) 4.22 (0.444)
Total protein (g/dL) 7.55 (0.670) 7.55 (0.664) 7.55 (0.661) 7.55 (0.678)
Sodium (mEq/dL) 139 (3.11) 139 (3.09) 139 (3.08) 139 (3.14)
White blood cell count (1000/µL) 7.19 (2.56) 7.20 (2.54) 7.20 (2.54) 7.20 (2.62)
  1. *Treated during 2000–2015. Does not include patients treated after 2015