Table 1 Characteristics of patients with a minimum of 1, 3, and 5 years of follow up time
1-year minimum (n = 146,182) | 3-year minimum (n = 110,559) | 5-year minimum (n = 84,189) | All (n = 182,772) | |
|---|---|---|---|---|
Age (years), mean (SD) | 52.5 (8.28) | 52.4 (8.08) | 52.2 (7.75) | 52.4 (8.32) |
Male, n (%) | 141,663 (96.9%) | 107,012 (96.8%) | 81,449 (96.7%) | 177,270 (97.0%) |
Race, n (%) | ||||
Black | 51,206 (35.0%) | 40,445 (36.6%) | 32,007 (38.0%) | 63,017 (34.5%) |
White | 74,948 (51.3%) | 56,817 (51.4%) | 42,834 (50.9%) | 93,240 (51.0%) |
Hispanic | 6646 (4.5%) | 4906 (4.4%) | 3639 (4.3%) | 8414 (4.6%) |
Other | 2561 (1.8%) | 1913 (1.7%) | 1427 (1.7%) | 3212 (1.8%) |
Missing | 10,821 (7.4%) | 6478 (5.9%) | 4282 (5.1%) | 14,889 (8.1%) |
BMI, mean (SD) | 27.5 (5.24) | 27.5 (5.23) | 27.6 (5.23) | 27.4 (5.24) |
History of alcohol use disorder | 73,961 (50.6%) | 56,466 (51.1%) | 43,473 (51.6%) | 93,045 (50.9%) |
History of substance use disorder | 75,350 (51.5%) | 58,339 (52.8%) | 45,478 (54.0%) | 94,167 (51.5%) |
Diabetes mellitus | 47,846 (32.7%) | 37,977 (34.3%) | 30,125 (35.8%) | 57,889 (31.7%) |
Human immunodeficiency virus | 4085 (2.8%) | 3373 (3.1%) | 2738 (3.3%) | 4863 (2.7%) |
Received antiviral treatment*, n (%) | 75,820 (51.9%) | 61,435 (55.6%) | 49,338 (58.6%) | 95,630 (52.3%) |
SVR, n (%) | 69,475 (47.5%) | 56,534 (51.1%) | 45,629 (54.2%) | 76,854 (42.0%) |
Baseline laboratory values, mean (SD) | ||||
APRI | 0.648 (0.692) | 0.609 (0.510) | 0.585 (0.473) | 0.668 (0.686) |
Albumin (g/dL) | 3.99 (0.447) | 4.01 (0.437) | 4.01 (0.430) | 3.98 (0.461) |
Alanine aminotransferase (U/L) | 65.8 (53.6) | 64.2 (52.0) | 63.3 (50.7) | 67.1 (55.9) |
Aspartate aminotransferase (U/L) | 51.5 (33.4) | 49.7 (31.6) | 48.6 (30.6) | 52.5 (34.3) |
Total bilirubin (mg/dL) | 0.706 (0.407) | 0.696 (0.373) | 0.691 (0.369) | 0.716 (0.472) |
Blood urea nitrogen (mmol/L) | 14.1 (7.15) | 14.0 (6.84) | 14.0 (6.61) | 14.1 (7.44) |
Chloride (mmol/L) | 103 (3.57) | 103 (3.52) | 103 (3.51) | 103 (3.60) |
Creatinine (mg/dL) | 1.04 (0.743) | 1.04 (0.713) | 1.04 (0.686) | 1.05 (0.769) |
Glucose (mg/dL) | 115 (59.6) | 115 (59.5) | 115 (59.6) | 115 (59.5) |
Hemoglobin (g/dL) | 14.9 (1.59) | 15.0 (1.56) | 15.0 (1.54) | 14.9 (1.62) |
INR | 1.05 (0.282) | 1.05 (0.287) | 1.05 (0.278) | 1.06 (0.282) |
Platelet (1000/µL) | 229 (72.5) | 231 (71.3) | 233 (70.7) | 228 (73.7) |
Potassium (mEq/dL) | 4.23 (0.441) | 4.23 (0.439) | 4.23 (0.438) | 4.22 (0.444) |
Total protein (g/dL) | 7.55 (0.670) | 7.55 (0.664) | 7.55 (0.661) | 7.55 (0.678) |
Sodium (mEq/dL) | 139 (3.11) | 139 (3.09) | 139 (3.08) | 139 (3.14) |
White blood cell count (1000/µL) | 7.19 (2.56) | 7.20 (2.54) | 7.20 (2.54) | 7.20 (2.62) |