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Table 4 Degree of detection and acceptance of the AEMPS safety alerts in 2016, 2017, and 2018

From: Safer prescription of drugs: impact of the PREFASEG system to aid clinical decision-making in primary care in Catalonia

  2016 2017 2018
AEMPS alert Alerts Alerts accepted % Accepted Alerts Alerts accepted % Accepted Alerts Alerts accepted % Accepted
"TRIPLE WHAMMY"* 46,020 13,867 30 76,107 18,992 25 73,860 15,988 22
DICLOFENAC 7288 2588 36 5734 1774 31 5137 1511 29
COXIBS 3131 888 28 2535 616 24 2986 644 22
ACECLOFENAC 805 204 25 665 127 19 487 101 21
ESCITALOPRAM 645 204 32 270 95 35 305 72 24
CITALOPRAM 495 189 38 217 67 31 302 104 34
CILOSTAZOL 193 70 36 181 66 36 289 65 22
AGOMELATINE 133 54 41 175 54 31 249 72 29
IVABRADINE 130 51 39 153 56 37 200 48 24
CANAGLIFLOZIN 128 42 33 177 40 23
TRIMETAZIDINE 115 62 54 82 36 44 111 47 42
RALOXIFENE and BAZEDOXIFENE 106 64 60 23 11 48 30 20 67
STRONTIUM RENALATE 53 39 74 21 11 52 22 5 23
ALISKIREN 32 21 66 17 11 65 3 3 100
Total 59,146 18,301 31 86,308 21,958 25 84,158 18,720 22
  1. *Triple Whammy: NSAIDs + RAS inhibitors + diuretics