Table 3 Top 10 alerts related to drug interactions between January 2016 and December 2018
Original active ingredient | Conflicting active ingredient | Alerts generated | Acceptance (%) |
|---|---|---|---|
Ibuprofen | Acetylsalicylic acid | 97,847 | 19 |
Amlodipine | Simvastatin | 85,358 | 24 |
Naproxen | Acetylsalicylic acid | 64,913 | 16 |
Simvastatin | Amlodipine | 59,453 | 26 |
Dexketoprofen | Acetylsalicylic acid | 32,455 | 16 |
Acenocoumarol | Simvastatin | 31,349 | 29 |
Simvastatin | Acenocoumarol | 31,349 | 26 |
Tramadol and paracetamol | Citalopram | 27,479 | 24 |
Tramadol and paracetamol | Sertraline | 26,872 | 24 |
Diclofenac | Acetylsalicylic acid | 25,292 | 24 |
Enoxaparin | Acetylsalicylic acid | 23,715 | 16 |