PREFASEG | 2016 | 2017 | 2018 | Sum 2016–2018 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Type of MRP alert | Alerts generated | Alerts accepted | % Accepted alerts | Alerts generated | Alerts accepted | % Accepted alerts | Alerts generated | Alerts accepted | % Accepted alerts | Alerts generated | Alerts accepted | % Accepted alerts |
Interactions | 439,507 | 118,485 | 27 | 550,692 | 138,947 | 25 | 701,687 | 166,452 | 24 | 1,691,886 | 423,884 | 25 |
Duplicate therapies | 426,506 | 141,371 | 33 | 463,418 | 136,097 | 29 | 546,797 | 148,943 | 27 | 1,436,721 | 426,411 | 30 |
Advised due to age (> 75 years) | 108,974 | 32,345 | 30 | 144,807 | 41,740 | 29 | 188,139 | 50,299 | 27 | 441,920 | 124,384 | 28 |
AEMPS safety alerts | 59,146 | 18,301 | 31 | 86,308 | 21,958 | 25 | 84,158 | 18,720 | 22 | 229,612 | 58,979 | 26 |
Contraindications due to health issues | 35,164 | 13,771 | 39 | 67,452 | 21,330 | 32 | 105,749 | 28,390 | 27 | 208,365 | 63,491 | 30 |
Teratogens in pregnancy | 11,721 | 4200 | 36 | 10,938 | 3830 | 35 | 11,404 | 3709 | 33 | 34,063 | 11,739 | 34 |
Combinations of anticholinergic drugs | 1077 | 423 | 39 | 2619 | 863 | 33 | 3171 | 877 | 28 | 6867 | 2163 | 31 |
Suspicions of hypersensitivity | 76,883 | 28,952 | 38 | 84,099 | 29,759 | 35 | 93,852 | 30,568 | 33 | 254,834 | 89,279 | 35 |
Adverse drug reactions | 15,397 | 4884 | 32 | 23,712 | 6927 | 29 | 36,489 | 10,018 | 27 | 75,598 | 21,829 | 29 |
Totals | 1,174,375 | 362,732 | 31 | 1,434,045 | 401,451 | 28 | 1,771,446 | 457,976 | 26 | 4,379,866 | 1,222,159 | 28 |