Skip to main content
Fig. 1 | BMC Medical Informatics and Decision Making

Fig. 1

From: Efficient framework for predicting MiRNA-disease associations based on improved hybrid collaborative filtering

Fig. 1

Flowchart of miRNA-disease association prediction based on HCFMDA. (1) Construct integrated similarities by incorporating the miRNA functional similarity, disease semantic similarity, Gaussian kernel similarity and experimentally verified MDA; (2) Calculate and fuse three different association sources: similar disease associations (SDA), similar miRNA associations (SMA), and similar disease-miRNA associations (SDMA); (3) Apply the proposed model to calculate the recommend score for test associations. Then, the predicted disease-related miRNAs could be further analyzed and experimentally validated

Back to article page

BMC Medical Informatics and Decision Making

ISSN: 1472-6947

Contact us