Table 2 Basic structural elements in the identified DAs

Target group

Women with BRCA1/2 mutation

[57, 58]

Women at high risk of breast cancer

[59, 61, 64]

Women at high risk of ovarian cancer

[60, 62, 63]

Addressed target decision

Preventive options related to breast and ovarian cancer

[58]

Preventive options only/mainly related to breast cancer

[57, 59, 61, 64]

Preventive options only/mainly related to ovarian cancer

[60, 62, 63]

Medical information

Family history of breast and/or ovarian cancer (explanations, even if brief)

[59,60,61,62,63,64]

Impact of a pathogenic BRCA1/2 mutation (reason for high risk of breast and/or ovarian cancer)

[57,58,59,60,61,62,63,64]

Average morbidity rates for breast and/or ovarian cancer (text and/or number values and/or graphics)

[57, 58, 61,62,63,64]

(a) Lifetime risks

(a) [57, 58, 61,62,63]

(b) Time and/or age-related morbidity rates

(b) [62,63,64] (example information)

Preventive options (explanations, even if brief)

[57,58,59,60,61,62,63,64]

Outcomes with and without preventive measure (text and/or number values and/or graphics)

[57, 58, 60,61,62,63,64]

Consequences of the different preventive measures (text and/or number values and/or graphics)

[57,58,59,60,61,62,63,64]

Hormone replacement therapy to counteract consequences of risk-reducing removal of both ovaries and Fallopian tubes

[60, 62, 63]

Benefits and risks of the different preventive measures and/or comparison of the options (option grid)

[57, 59,60,61,62,63,64]

Personal stories (testimonies)

[61, 64]

Appendix with fact boxes

[57, 61]

Tools for decision-making support

General information on dealing with decision-making

[57, 64]

Step-by-step guide to decision-making

[57, 62, 63]

Tools to assist with clarifying own values and preferences, e.g

To reflect on personal opinions regarding the advantages and disadvantages of the options by answering set response options (box-ticking) and/or using note spaces for free-form reflections

To reflect on the current tendency towards or against a certain option

[57, 61,62,63]

Question lists addressing medical information and/or doctor-patient dialogue

[60, 64]

Other

Glossary

[57, 58]

Contact addresses and/or internet links

[58, 62,63,64]

References, further literature

[57,58,59,60,61,62,63,64]