Table 5 Adverse drug reactions obtained from PubMed and probability of their occurrence according to our model
From: Prediction of adverse drug reactions based on knowledge graph embedding
Study | Drug | Adverse Drug Reaction | Probability |
|---|---|---|---|
Kuniyosh et al. [27] | Atorvastatin (DB01076) | Liver injury (C0160390) | 0.955 |
Brehm et al. [28] | Acetaminophen (DBDB00316) | Acute liver injury (C2242583) | 0.62 |
Moon et al. [29] | Albendazole (DB00518) | Liver injury (C0160390) | 0.919 |
Kopecky et al. [30] | Nivolumab (DB09035) | Liver injury (C0160390) | 0.854 |
Gisi et al. [31] | Azathioprine (DB00993) | Hepatitis cholestatic (C0149904) | 0.958 |
Carretero et al. [32] | Osimertinib (DB09330; one of the tyrosine-kinase inhibitors) | Hepatotoxicity (C0235378) | 0.797 |
Ota et al. [33] | Crizotinib (DB08865) | Liver injury (C0160390) | 0.83 |
Kawaguchi et al. [18] | Laninamivir octanoate (DB11888) | Liver injury (C0160390) | Drug not in KG |
Kwan et al. [19] | Pembrolizumab (DB09037) | Hepatotoxicity (C0235378) | Drug not in KG |
Rajan et al. [34] | Sevoflurane anaesthesia (DB01236) | Hepatotoxicity (C0235378) | 0.959 |