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Table 3 Analysis of Cohort Characteristics Between Mayo and TMC

From: Assessment of the impact of EHR heterogeneity for clinical research through a case study of silent brain infarction

VariablesMayo (n = 500)TMC (n = 500)p Value
Age (mean)65 (+ − 10.6)66 (+ − 9.7)0.1197
Gender (female)243 (48.6)274 (54.8)0.0576
SBI57 (11.4)38 (7.6)0.0516
Acuity
 Acuity/subacute6 (1.2)6 (1.2)1.0000
 Chronic44 (8.8)29 (5.8)0.0882
 Non-specified7 (1.4)3 (0.6)0.3407
Location
 Lacunar/subcortical27 (5.4)10 (2.0)0.0065
 Cortical/juxtacortical9 (1.8)13 (2.6)0.5188
 Both0 (0)3 (0.6)0.2492
 Non-specified21(4.2)12 (2.4)0.1558
WMD291 (58.2)264 (52.8)0.9800
WMD grading
 Mild191 (38.2)154 (30.8)0.0165
 Mild/moderate21 (4.2)0 (0.0)7.6963e-7
 Moderate42 (8.4)45 (9.0)0.8226
 Moderate/severe2 (0.4)0 (0)0.4995
 Severe8 (1.6)11 (2.2)0.6443
 No mention of quantification27 (5.4)54 (10.8)0.0024
  1. Definition of abbreviations: CI confidence interval, OR odds ratio