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Table 5 Feature importance ranking of 4-hydroxy-2-nonenal (HNE)-protein adducts and autoantibody isotypes against unmodified and HNE-modified peptides in rheumatoid arthritis (RA) patients versus healthy controls (HCs) and osteoarthritis (OA) patients

From: Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women

HC versus RA OA versus RA
Score Feature Score Feature
0.3496 IgM anti-HPT78−108 HNE 0.352 IgM anti-HPT78−108 HNE
0.2967 IgM anti-IGKC2−19 0.245 IgM anti-IGKC2−19
0.2921 IgM anti-IGKC2−19 HNE 0.223 IgM anti-IGKC2−19 HNE
0.1689 IgM anti-THRB HNE 0.186 IgG anti-HPT78−108 HNE
0.1395 IgG anti-THRB328−345 0.172 IgG anti-CFAH1121−1230
0.1382 IgG anti-THRB328−345 HNE 0.139 HNE adducts
0.1312 IgG anti-HPT78−108 HNE 0.134 IgM anti-THRB328−345 HNE
0.1186 IgG anti-IGKC2−19 0.128 IgG anti-CFAH1121−1230 HNE
0.1123 IgG anti-CFAH1121−1230 0.126 IgG anti-HPT78−108
0.1108 IgM anti-CFAH1121−1230 0.114 IgG anti-THRB328−345
0.1007 IgG anti-HPT78−108   
0.0994 HNE adducts   
0.0980 IgG anti-CFAH1121−1230 HNE