BMC Medical Informatics and Decision Making

Table 5 Feature importance ranking of 4-hydroxy-2-nonenal (HNE)-protein adducts and autoantibody isotypes against unmodified and HNE-modified peptides in rheumatoid arthritis (RA) patients versus healthy controls (HCs) and osteoarthritis (OA) patients

From: Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women

HC versus RA		OA versus RA
Score	Feature	Score	Feature
0.3496	IgM anti-HPT⁷⁸⁻¹⁰⁸ HNE	0.352	IgM anti-HPT⁷⁸⁻¹⁰⁸ HNE
0.2967	IgM anti-IGKC²⁻¹⁹	0.245	IgM anti-IGKC²⁻¹⁹
0.2921	IgM anti-IGKC²⁻¹⁹ HNE	0.223	IgM anti-IGKC²⁻¹⁹ HNE
0.1689	IgM anti-THRB HNE	0.186	IgG anti-HPT⁷⁸⁻¹⁰⁸ HNE
0.1395	IgG anti-THRB^328−345	0.172	IgG anti-CFAH^1121−1230
0.1382	IgG anti-THRB^328−345 HNE	0.139	HNE adducts
0.1312	IgG anti-HPT⁷⁸⁻¹⁰⁸ HNE	0.134	IgM anti-THRB^328−345 HNE
0.1186	IgG anti-IGKC²⁻¹⁹	0.128	IgG anti-CFAH^1121−1230 HNE
0.1123	IgG anti-CFAH^1121−1230	0.126	IgG anti-HPT⁷⁸⁻¹⁰⁸
0.1108	IgM anti-CFAH^1121−1230	0.114	IgG anti-THRB^328−345
0.1007	IgG anti-HPT⁷⁸⁻¹⁰⁸
0.0994	HNE adducts
0.0980	IgG anti-CFAH^1121−1230 HNE

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ISSN: 1472-6947

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