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Fig. 3 | BMC Medical Informatics and Decision Making

Fig. 3

From: Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women

Fig. 3Fig. 3

Dot plots and receiver operating characteristics (ROC) curves of serum concentrations (absorbance units at 450 nm) of autoantibody isotypes: IgG anti-complement factor H (CFAH)1211–1230 (a), IgG anti-CFAH1211−1230 4-hydroxy-2-nonenal (HNE) (b), IgM anti-CFAH1211−1230 (c), IgM anti-CFAH1211−1230 HNE (d), IgG anti-haptoglobin (HPT)78–108 (e), IgG anti-HPT78−108 HNE (f), IgM anti-HPT78−108 (g), IgM anti-HPT78−108 HNE (h), IgG anti-immunoglobulin kappa chain C region (IGKC)2–19 (i), IgG anti-IGKC2−19 HNE (j), IgM anti-IGKC2−19 (k), IgM anti-IGKC2−19 HNE (l), IgG anti-prothrombin (THRB)328–345 (m), IgG anti-THRB328−345 HNE (n), IgM anti-THRB328−345 (o), and IgM anti-THRB328−345 HNE (p) in healthy controls (HCs), osteoarthritis (OA) patients, and rheumatoid arthritis (RA) patients using an ELISA. OD450, optical density at 450 nm. ANOVA was used to test levels of autoantibody isotypes among patients with RA and OA, and HCs. Scheffe’s post-hoc test was applied to compare the mean difference between any two groups. Values of mean ± 1 standard deviation are also indicated in the figure as horizontal lines

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