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Fig. 1 | BMC Medical Informatics and Decision Making

Fig. 1

From: Computational analysis to repurpose drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2

Fig. 1

(Upper) Activated signaling pathways (with 244 genes) within NHBE and also appeared in lung A549_ACE2 and CALU3 cells after SARS-CoV-2 infection. Red nodes are transcription factors (TFs); green—receptors; purple—ligands; orange—activated target genes of TFs; and cyan—the linking genes. (Lower) 220 drugs (cyan) (with 97 target genes) targeting on the activated signaling pathways

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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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