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Table 9 Summary statistics for the features of our dataset

From: CNFE-SE: a novel approach combining complex network-based feature engineering and stacked ensemble to predict the success of intrauterine insemination and ranking the features

Feature name Min First Q Median Third Q Max Mean SD
Time diff between cycles 0 0 0 2 6.1 1.59 4.82
  0 0 0 1 6.9 1.25 3.83
Age_x 17 25 28 31 43 28.29 4.29
  16 26 29 32 47 28.97 4.68
Family demographic information (Education_x) 1 3 3 5 7 3.43 1.17
  1 3 3 5 7 3.4 1.22
Duration of marriage (years) 0.42 4 6 7 23 6 2.94
  0.25 4 6 7.5 26 6.31 3.19
Duration of infertility (Years) 0.25 2.5 4 5 15 4.36 2.62
  0.17 2.84 4.5 6 19 4.66 2.85
Menstrual HX (menarche old year) 9 13 13 14 27 13.35 1.46
  9 13 13 14 27 13.29 1.42
Current contraception duration 0 0 0 0 3 0.02 0.17
  0 0 0 0 8 0.01 0.19
Summary-Gravida 0 0 0 0 6 0.29 0.66
  0 0 0 0 6 0.26 0.61
Summary-para 0 0 0 0 3 0.08 0.31
  0 0 0 0 4 0.08 0.3
Abortion-early 0 0 0 0 4 0.17 0.48
  0 0 0 0 6 0.15 0.45
Abortion-late 0 0 0 0 3 0.02 0.16
  0 0 0 0 4 0.01 0.11
Summary-IUFD 0 0 0 0 2 0.01 0.11
  0 0 0 0 2 0 0.07
Summary-mole 0 0 0 0 1 0 0.06
  0 0 0 0 2 0 0.04
Summary-EP 0 0 0 0 1 0.01 0.11
  0 0 0 0 1 0.02 0.12
Summary-Preterm 0 0 0 0 3 0.03 0.2
  0 0 0 0 5 0.02 0.16
Summary-term 0 0 0 0 2 0.06 0.25
  0 0 0 0 4 0.06 0.26
Summary-living child 0 0 0 0 2 0.06 0.24
  0 0 0 0 4 0.06 0.25
IUI Hx-total 2 2 2 3 10 2.73 1.47
  2 2 2 3 11 2.7 1.4
Result-failed 0 0 0 0.41 6 0.39 0.78
  0 0 0 1 10 0.41 0.78
Result-pregnant 0 0 0 0 2 0.04 0.2
  0 0 0 0 2 0.02 0.14
Summary of ART cycle-IVF 0 0 0 0 2 0.01 0.13
  0 0 0 0 6 0.03 0.24
Summary of ART cycle-ZIFT 0 0 0 0 1 0 0.02
  0 0 0 0 3 0 0.06
Summary of ART cycle-E.T freeze 1 1 1 1 4 1.01 0.11
  1 1 1 1 5 1.01 0.1
Summary of ART cycle-Total 0 0 0 0 4 0.02 0.2
  0 0 0 0 9 0.04 0.31
Physical exam-height 142 158 161.05 165 187 161.61 5.74
  142 157 161.05 164 187 160.96 5.7
Physical exam-weight 40 61 67.31 74 170 68.14 12.54
  36 60 67 73 171 67.18 11.65
Physical exam-BMI 15.02 23.53 25.93 28.04 52.11 26.01 4.23
  14.19 23.34 25.93 28.01 57.09 25.92 4.22
IUI clinic-number of cycle 1 1 1 2 5 1.35 0.63
  1 1 1 2 7 1.31 0.59
Infertility medical treatment-Starting day of Stimulation (menstrual day) 1 3 3 3.42 8 3.39 0.73
  1 3 3 3.42 14 3.42 0.82
Letrosol dose (mg/day) 0 0 0 1.12 7.5 1.28 2.04
  0 0 0 1.12 7.5 1.1 1.9
Letrosol duration 0 0 0 1.19 12 1.34 2.17
  0 0 0 1.19 15 1.16 2.05
Letrosol start day of stimulation 0 0 0 0.77 5 0.86 1.41
  0 0 0 0.77 17 0.76 1.38
Clomiphen dose (mg/day) 0 0 59.87 100 150 57.97 45.82
  0 0 100 100 150 60.19 45.54
Clomiphen duration 0 0 3 5 12 2.94 2.33
  0 0 5 5 15 3.07 2.36
Clomiphen Start day of stimulation 0 0 2.08 3 6 2 1.66
  0 0 2.08 3 18 2.09 1.7
Summary of foliculogenesis-duration of stimulation 1 9 10.23 11 25 10.41 2.59
  1 9 10.23 11 31 10.2 2.63
Fostimon dose IU 0 0 0 77.03 337.5 91.4 23.39
  0 0 0 77.03 247.5 74.61 18.54
Gonal.F dose IU 0 0 0 0 3750 60.96 26.71
  0 0 0 0 6847 60.2 23.93
Menopour Dose IU 0 0 0 0 2700 10.65 125.74
  0 0 0 0 3300 9.74 104.92
HMG dose IU 0 0 0 150 2625 116.59 221.67
  0 0 0 150 3300 125.45 230.94
Merional dose IU 0 0 0 0 3900 66.25 295.78
  0 0 0 0 9075 44.76 202.57
Hemogon dose IU 0 0 0 0 1200 3.09 44.01
  0 0 0 0 3000 4.95 55.65
Menogan dose IU 0 0 0 0 3450 46.63 195.23
  0 0 0 0 3600 44.2 163.25
Bravelle dose IU 0 0 0 0 1050 7.93 57.94
  0 0 0 0 2100 9.55 77.96
Gonadotropin total dose 0 225 375 450 4500 453.57 502.6
  0 225 375 450 4424 411.52 410.99
Esteradiol dose 0 0 0 0 6 0.33 0.99
  0 0 0 0 8 0.42 1.16
Esteradiol duration 0 0 0 0 15 0.25 0.95
  0 0 0 0 14 0.3 0.96
No of dominate follicle at HCG day_17 0 1 1.65 2 10 1.81 1.46
  0 1 1.65 2 11 1.61 1.38
No of dominate follicle at HCG day_18 0 0 0.95 1 7 0.97 0.95
  0 0 0.94 1 9 0.92 0.87
HCG day endometrium (endometrial thickness) 4.3 8 8.51 9 19 8.67 1.47
  1 8 8.52 9 18 8.48 1.51
Age_y 20 30 33 35 72 32.82 4.7
  20 30 33 36 80 33.35 4.88
Family demographic information (Education_y) 1 2 3 4 7 3.38 1.23
  1 2 3 4 7 3.31 1.25
Specimen characteristics-abstinence 0.41 3 4 4.59 20 4.42 1.79
  0.41 3 4 4.59 20 4.43 1.89
Specimen characteristics-volume (normal range 2.7 mL) 0.1 2 3.2 4 9.5 3.29 1.56
  0.1 2 3 4 10.5 3.23 1.54
Specimen characteristics-PH 6 7.8 7.8 7.8 8.5 7.8 0.11
  6 7.8 7.8 7.8 85 7.8 0.10
Specimen characteristics liquefaction time (normal range15-30 min) 20 20 20 30 60 26.10 8.60
  15 20 20 25.53 60 25.34 8.48
Sperm concentration- total sperm count 10 104 170.1 202.72 399 165.46 84.57
  10 92.5 168 204 400 163.60 88.18
Sperm motility-total motility (normal range 50) 10 40 57.3 72.22 98.8 55.94 19.87
  10 37.6 55.9 72.22 100 54.51 21.10
Total motile sperm count 1.14 41.06 86.70 132.90 354.88 95.29 64.21
  1 35.52 81.55 132.90 370.11 93.71 69.08
Sperm motility-shaking grade 0 0 0 0 5 0.03 0.36
  0 0 0 0 15 0.03 0.48
Sperm motility-grade I- 0 0 0 0 19 0.12 1.14
  0 0 0 0 34.3 0.12 1.16
Sperm motility-grade I (grade d) 0 0 3.6 8.2 37.3 5.3 5.92
  0 0 3.6 8.2 46.4 5.40 6.18
Sperm motility Grade II- 0 0 0 0 50.3 0.27 3.04
  0 0 0 0 57.6 0.21 2.57
Sperm motility Grade II (grade c) 0 10.27 26.7 36.8 64.7 24.11 16.26
  0 11.9 26.4 36.7 70.0 24.25 15.97
Sperm motility Grade II +  0 0 0 0 23.2 0.01 0.58
  0 0 0 0 37.3 0 0.38
Sperm motility Grade III (a + b) 0 2.7 9.8 18.6 48.9 11.96 10.76
  0 3.3 9.8 17.8 49.8 11.96 10.82
Sperm morphology-normal morphology (normal range 30) 0 4 5.62 7 20 5.72 2.99
  0 4 5.62 7 28 5.6 3.1
Sperm morphology-abnormal morphology (normal range 70) 80 93 94.38 96 100 94.27 2.99
  72 93 94.38 96 133 94.4 3.13
Sperm morphology-amorph 0 69 76 80 92 68.59 22.61
  0 68.66 75 80 96 68.68 21.7
Sperm morphology-double head 0 0 0 1.02 8 0.85 1.20
  0 0 1 2 11 1.02 1.36
Sperm morphology-giant head 0 1 2 4 20 2.40 2.51
  0 1 2 4 25 2.53 2.61
Sperm morphology-pin head 0 1 2 4 30 2.95 3.47
  0 1 2 4 30 3.14 3.37
Sperm morphology-round head 0 1 2 4 20 2.85 2.92
  0 1 2 4 20 2.66 2.69
Sperm morphology-double tail 0 0 0 0 4 0.14 0.47
  0 0 0 0 10 0.19 0.63
Sperm morphology-coiled tail 0 1 3 5 25 3.79 3.48
  0 2 3 6 28 4.17 3.84
Sperm morphology-short tail 0 1 1 2.31 24 1.90 2.37
  0 1 1 3 28 2.20 2.75
Sperm morphology-cytoplasmic droplet 1 4 7 14 20 8.08 4.94
  1 4 7 12 30 8.12 4.85
Other tests-germinal cell 0 1 2 3 15 2.14 1.87
  0 1 2 3 21 2.20 1.79
Therapeutic duration of liquefaction (min) 5 15 16.13 16.13 145 16.16 5.70
  5 15 16.13 16.13 200 16.15 5.22
Therapeutic volume 0.5 2.5 3.59 4 13 3.6 1.64
  0.01 2.5 3.5 4 13 3.54 1.66
Therapeutic PH 5 7.76 7.8 7.8 7.9 7.77 0.09
  0.33 7.76 7.8 7.8 10 7.76 0.19
Before processing motility 0.04 0.3 0.37 0.45 0.92 0.38 0.14
  0.01 0.28 0.37 0.45 0.98 0.37 0.14
Before processing sperm concentration 4 45 54.62 68 110 55.57 18.7
  1 42 54.62 68 110 54.15 20.23
After processing motility 0.2 0.96 0.98 1 1 0.97 0.06
  0.02 0.96 0.98 1 1 0.96 0.09
Post wash total motile sperm count 1 127.4 209.88 264.87 460 213.81 27.49
  0.16 102.9 195 252 450 198.81 35.09
After processing sperm concentration 2 50 60.7 72 120 60.82 21.94
  1 42 60.7 72 120 57.23 24.87
  1. *Statistical description of numeric variables: Each row is divided into two parts in which the top row is related to the positive class and the bottom row represents the negative class