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Table 2 Clinical characteristics and outcomes by occurrence of hyperchloremia in days 1–7

From: Hyperchloremia in critically ill patients: association with outcomes and prediction using electronic health record data

  Hyperchloremic Non-hyperchloremic All patients  
(n = 18181) (n = 29893) (n = 48074) p value
Demographics     
 Age, median (IQR) 66.9 (53.8–78.5) 65.0 (52.4–77.4) 65.7 (52.9–77.8) < 0.001
 Female, n (%) 8324 (45.8) 12684 (42.4) 21008 (43.7) < 0.001
Race, n (%)     
 Asian 518 (2.8) 603 (2.0) 1121 (2.3) < 0.001
 Black 1614 (8.9) 3006 (10.1) 4620 (9.6)  
 Hispanic 598 (3.3) 1053 (3.5) 1651 (3.4)  
 White 12930 (71.1) 21477 (71.8) 34407 (71.6)  
 Other (unreported) 2521 (13.9) 3754 (12.6) 6275 (13.1)  
Comorbid conditions, n (%)     
 Cancer 1488 (8.2) 3088 (10.3) 4576 (9.5) < 0.001
 Cardiovascular 9838 (54.1) 16385 (54.8) 26223 (54.5) 0.137
 Diabetes 4625 (25.4) 8436 (28.2) 13061 (27.2) < 0.001
 Hepatic 1989 (10.9) 2960 (9.9) 4949 (10.3) < 0.001
 Renal 2589 (14.2) 5279 (17.7) 7868 (16.4) < 0.001
 Respiratory 3434 (18.9) 7263 (24.3) 10697 (22.2) < 0.001
 Multiple comorbidities 15304 (84.2) 24819 (83.0) 40123 (83.5) 0.001
Outcome, n (%)     
 ICU mortality 1855 (10.2) 1703 (5.7) 3558 (7.4) < 0.001
 New AKI by day 7 7788 (42.8) 9445 (31.6) 17233 (35.8) < 0.001
 MODS on day 7 1109 (6.1) 781 (2.6) 1890 (3.9) < 0.001