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Fig. 1 | BMC Medical Informatics and Decision Making

Fig. 1

From: Network analysis of autistic disease comorbidities in Chinese children based on ICD-10 codes

Fig. 1

Description of the procedures and steps used in this study. In the data preparation stage, the diagnostic codes for children with autism were extracted from the hospital CDR (Clinical Data Repository) database and were then generalized in the next step. In the disease rule discovery stage, the FP-growth algorithm was first applied to discover all the rules for the relationships between the diseases, and the discovered rules were examined internally using 10-fold cross-validation. All of the rules were further validated by using the public database (COHD) and by searching the literature. Finally, a disease network was constructed using Cytoscape 3.7

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