Fig. 5

Screenshot of Sparklis on PEGASE data illustrating the process of building a query (version 2019–05). The current query (at the top) selects PT in MedDRA whose finding site is “Skin and subcutaneous tissue structure”, and whose associated morphology is various morphologic abnormalities. A first abnormality, “Blister”, has already been selected, and the user is in the process of selecting (at the center) a disjunction of three more abnormalities (“Vesicle”, “Vesiculobullous rash”, “Vesicular rash”). The keyword “vesic” was input at the top of the list of suggested terms in order to ease their retrieval among a long list of suggestions. Sparklis suggests changes to be applied to the current focus (here, the focus is on the associated morphology of the selected PT): at the middle left, Sparklis suggests types and relations to refine the query; at the middle center, terms denoting associated morphologies relevant to the query; and at the middle right, query modifiers and operators (e.g., “and”, “or”). The table of results of the current query is shown at each step. Here, it shows the selected PT along with their finding sites and associated morphologies