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Table 6 Uni- and multi-variable survival analysis for CBMs were performed through KM and Cox proportional hazard model, respectively

From: Leveraging hybrid biomarkers in clinical endpoint prediction

Biomarkers Univariable Multivariable
HR 95% CI HR 95% CI
Demographic factors
Age
  ≤ 70 1   1  
  > 70 2.235 1.097–4.556a 2.257 1.240–4.111
Gender
 Male 1   
 Female 1.015 0.560–1.837
Weights
  ≤ 150 1   
  > 150 1.070 0.604–1.897
Smoking Status
 Yes 1   
 No 1.623 0.872–3.021
Clinical factors
Primary Tumor
  ≤ T2 1   
  > T2 0.904 0.446–1.830
Lymph Node
 N0 1   1  
  ≥ N1 3.797 1.038–13.887a 4.163 1.858–9.326
Metastasis
 M0 1   
 M1 4.863 0.238–99.479a
Histology
 Squamous 1   
 Non-Squamous 1.194 0.582–2.452
Tumor size
 Longest diameter 1.059 1.010–1.110a  
  1. * representing significant data; HR Hazard ration, CI Confidence interval