Evaluation of standard and semantically-augmented distance metrics for neurology patients

Hier, Daniel B.; Kopel, Jonathan; Brint, Steven U.; Wunsch, Donald C.; Olbricht, Gayla R.; Azizi, Sima; Allen, Blaine

doi:10.1186/s12911-020-01217-8

BMC Medical Informatics and Decision Making

Table 2 Four test groups and 32 diagnoses used in clustering and classification analyses. The first column is an abbreviation used in Tables and Figures. Typical findings are listed illustratively for non-neurologists and are not meant to be a definitive reference on each condition

From: Evaluation of standard and semantically-augmented distance metrics for neurology patients

	Test Group	Typical Findings	N
	Patient with weakness	Group 1	148
GBS	Guillain Barré syndrome*	weakness, areflexia, sensory loss, paresthesias	20
MYL	myelopathy	weakness, sensory level, urinary retention, hyperreflexia	29
CE	cauda equina	leg weakness, urinary retention, sensory loss	6
ALS	amyotrophic lateral sclerosis	weakness, hyperreflexia, fasciculations	21
MS	multiple sclerosis	weakness, sensory changes, hyperreflexia, diplopia	19
MYO	myopathy	proximal muscle weakness	15
MG	myasthenia gravis	weakness, diplopia, ptosis	18
PN	polyneuropathy	weakness, sensory loss, hyporeflexia	20
	Patient with abnormal movements	Group 2	75
HD	Huntington disease*	chorea, personality change	16
PAR	Parkinson disease*	tremor, bradykinesia, rigidity	19
PSP	progressive supranuclear palsy	bradykinesia, rigidity, gaze palsies	8
SND	striatonigral degeneration	bradykinesia, rigidity	8
ET	essential tremor	tremor	7
HB	hemiballismus	hemiballismus	4
DYS	dystonia	dystonia	9
WIL	Wilson disease*	tremor, ataxia, dystonia, bradykinesia, personality change	4
	Patient with altered mental status	Group 3	102
LBD	Lewy body dementia	dementia, bradykinesia, hallucinations	6
B12	B₁₂ deficiency	paresthesias, confusion, weakness, sensory loss	9
NPH	normal pressure hydrocephalus	urinary incontinence, dementia, gait apraxia	14
AW	acute Wernicke encephalopathy*	confusion, diplopia, ataxia, disorientation	19
CJD	Creutzfeldt-Jakob disease*	myoclonus, personality change, memory loss, disorientation	12
ALZ	Alzheimer disease*	amnesia, dementia	16
FTD	frontotemporal dementia	aphasia, dementia, executive dysfunction	14
SDH	subdural hematoma	headache, lethargy, weakness, confusion	12
	Patient with cranial neuropathy	Group 4	67
BPV	benign positional vertigo	vertigo	9
MNR	Meniere disease*	vertigo, dizziness, hearing loss	7
RH	Ramsay Hunt syndrome*	facial weakness, hearing loss	6
BEL	Bell palsy*	facial weakness	10
THD	third nerve palsy	diplopia, ptosis	8
AN	acoustic neuroma	tinnitus, hearing loss, nystagmus	11
ON	optic neuritis	blurred vision, papilledema	6
TN	trigeminal neuralgia	face pain	10

*The non-possessive form of eponymous diseases has been used uniformly [61]

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