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Table 3 Summary of the four PEDIS risk models. To support a more straightforward interpretation of the logistic regression model coefficients, we present them as odds ratios (OR) in this table; the logistic regression coefficients can be interpreted as odds ratios when exponentiated. The OR is the exponentiated median of the posterior coefficient distribution. Furthermore, the 95% HDI of the OR is presented. HDI is derived from the posterior distribution. Any value within the interval has a higher density than the values outside the HDI. The total mass of values inside the HDI is 95%

From: Predicting the amputation risk for patients with diabetic foot ulceration – a Bayesian decision support tool

Risk Factors (Predictors)

Any Amputation

Major Amputation

Non-Informed Model

Informed Model

Non-Informed Model

Informed Model

Beta-Coefficients

Odds Ratios

Beta-Coefficients

Odds Ratios

Beta-Coefficients

Odds Ratios

Beta-Coefficients

Odds Ratios

Perfusion

0.688 [0.264–1.152]

1.990 [1.302–3.164]

0.703 [0.352–1.116]

2.020 [1.422–3.052]

0.471 [−0.017–1.069]

1.601 [0.983–2.913]

0.586 [0.170–1.070]

1.798 [1.185–2.914]

Extend

1.484 [0.617–2.376]

4.411 [1.853–10.762]

1.283 [0.562–2.233]

3.609 [1.754–9.326]

0.985 [−0.079–2.665]

2.678 0.924–14.364]

0.799 [0.061–2.272]

2.222 [1.063–9.702]

Depth

0.665 [0.050–1.418]

1.945 [1.051–4.128]

0.656 [0.168–1.302]

1.927 [1.183–3.677]

0.932 [− 0.088–2.275]

2.540 [0.916–9.726]

0.694 [0.069–1.893]

2.001 [1.071–6.642]

Infection

− 0.112 [− 0.483–0.266]

0.894 [0.617–1.305]

−0.021 [− 0.439–0.368]

0.979 [0.644–1.446]

0.155 [− 0.296–0.635]

1.167 [0.744–1.888]

0.368 [− 0.108–0.757]

1.445 [0.898–2.131]

Sensation

0.037 [− 0.726–1.077]

1.037 [0.484–2.937]

0.516 [− 0.303–1.223]

1.675 [0.738–3.397]

0.076 [−0.861–1.782]

1.079 [0.423–5.943]

0.553 [− 0.404–1.639]

1.738 [0.668–5.149]

AUC Value

0.793

0.790

0.765

0.790

AUC HDI

[0.778–0.801]

[0.774–0.802]

[0.725–0.779]

[0.774–0.802]