Table 1 Clinical Characteristics of all patients included in the Irish prostate cancer risk calculator study cohort
From: A risk calculator to inform the need for a prostate biopsy: a rapid access clinic cohort
All patients (n = 4801) | PCa patients (n = 2548) | |||||
|---|---|---|---|---|---|---|
PCa | No PCa | P-value | High grade PCa | Low grade PCa | P-value | |
Patients | 2548 (53%) | 2253 (47%) | 1579 (62%) | 969 (38%) | ||
Median Age (mean) | 64.37 (63.70) | 63.00 (62.28) | < 0.001 (< 0.001) | 65.00 (64.40) | 63.01 (62.57) | < 0.001 (< 0.001) |
Family history of PCa | ||||||
Yes | 182 (7%) | 128 (6%) | < 0.001 | 114 (7%) | 68 (7%) | 0.173 |
Not recorded | 1919 (75%) | 1624 (72%) | 1171 (74%) | 748 (77%) | ||
No | 447 (18%) | 501 (22%) | 294 (19%) | 153 (16%) | ||
Median PSA (mean) | 7.18 (18.87) | 6.30 (7.31) | < 0.001 (< 0.001) | 8.02 (26.04) | 6.20 (7.17) | < 0.001 (< 0.001) |
DRE | ||||||
Normal | 1097 (43%) | 1283 (57%) | < 0.001 | 555 (35%) | 542 (56%) | < 0.001 |
Not recorded | 359 (14%) | 506 (22%) | 210 (13%) | 149 (15%) | ||
Abnormal | 1092 (43%) | 464 (21%) | 814 (52%) | 278 (29%) | ||
Previous negative biopsy | ||||||
Yes | 354 (14%) | 68 (20%) | < 0.001 | 152 (10%) | 202 (21%) | < 0.001 |
No | 2194 (86%) | 1810 (80%) | 1427 (90%) | 767 (79%) | ||
Gleason Score | ||||||
Gleason 6 | 969 (38%) | 969 (100%) | ||||
Gleason 7 | 1058 (42%) | 1058 (67%) | ||||
Gleason 8 | 301 (12%) | 301 (19%) | ||||
Gleason 9 | 201 (8%) | 201 (13%) | ||||
Gleason 10 | 19 (< 1%) | 19 (1%) | ||||