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Table 1 Clinical Characteristics of all patients included in the Irish prostate cancer risk calculator study cohort

From: A risk calculator to inform the need for a prostate biopsy: a rapid access clinic cohort

  All patients (n = 4801) PCa patients (n = 2548)
PCa No PCa P-value High grade PCa Low grade PCa P-value
Patients 2548 (53%) 2253 (47%)   1579 (62%) 969 (38%)  
Median Age (mean) 64.37 (63.70) 63.00 (62.28) < 0.001 (< 0.001) 65.00 (64.40) 63.01 (62.57) < 0.001 (< 0.001)
Family history of PCa
 Yes 182 (7%) 128 (6%) < 0.001 114 (7%) 68 (7%) 0.173
 Not recorded 1919 (75%) 1624 (72%)   1171 (74%) 748 (77%)  
 No 447 (18%) 501 (22%)   294 (19%) 153 (16%)  
Median PSA (mean) 7.18 (18.87) 6.30 (7.31) < 0.001 (< 0.001) 8.02 (26.04) 6.20 (7.17) < 0.001 (< 0.001)
DRE
 Normal 1097 (43%) 1283 (57%) < 0.001 555 (35%) 542 (56%) < 0.001
 Not recorded 359 (14%) 506 (22%)   210 (13%) 149 (15%)  
 Abnormal 1092 (43%) 464 (21%)   814 (52%) 278 (29%)  
Previous negative biopsy
 Yes 354 (14%) 68 (20%) < 0.001 152 (10%) 202 (21%) < 0.001
 No 2194 (86%) 1810 (80%)   1427 (90%) 767 (79%)  
Gleason Score
 Gleason 6 969 (38%)     969 (100%)  
 Gleason 7 1058 (42%)    1058 (67%)   
 Gleason 8 301 (12%)    301 (19%)   
 Gleason 9 201 (8%)    201 (13%)   
 Gleason 10 19 (< 1%)    19 (1%)