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Table 4 Top 15 ADRs ranked by AUPR

From: Towards early detection of adverse drug reactions: combining pre-clinical drug structures and post-market safety reports

ADR concept ID

ADR name

Number of positive drugs

AUPR

AUC

   

MGPS

LP-MGPS

MGPS

LP-MGPS

36009756

Anaphylactic reaction

373

0.968

0.973

0.779

0.798

35104877

Febrile neutropenia

52

0.968

0.972

0.955

0.962

35707713

Pancreatitis

197

0.956

0.959

0.862

0.865

36009762

Angioedema

328

0.949

0.955

0.794

0.807

35406359

Deafness

123

0.932

0.940

0.819

0.832

37019318

Renal failure

207

0.937

0.939

0.824

0.828

36009760

Anaphylactoid shock

151

0.869

0.928

0.681

0.756

35104879

Granulocytopenia

224

0.901

0.925

0.756

0.789

36009724

Stevens-Johnson syndrome

209

0.917

0.922

0.815

0.825

36516888

Rhabdomyolysis

90

0.914

0.920

0.866

0.868

35104103

Bone marrow failure

195

0.914

0.920

0.758

0.756

36009707

Erythema multiforme

252

0.911

0.918

0.777

0.782

35104281

Haemolytic anaemia

128

0.901

0.916

0.788

0.785

35909518

Hepatic failure

136

0.910

0.915

0.813

0.820

35104101

Aplastic anaemia

109

0.885

0.913

0.748

0.802

  1. The bold in the table is maximum values of that evaluation metrics