Towards early detection of adverse drug reactions: combining pre-clinical drug structures and post-market safety reports

Table 3 Comparison of the proposed methods and corresponding baseline methods on all years reports

Method	AUC	AUPR	Precision	Recall	Accuracy	F1
PRR	0.716	0.517	0.786	0.466	0.629	0.586
LP-PRR	0.728	0.534	0.801	0.478	0.644	0.588
ROR	0.716	0.518	0.786	0.466	0.629	0.585
LP-ROR	0.728	0.534	0.801	0.477	0.643	0.588
MGPS	0.727	0.544	0.746	0.483	0.649	0.586
LP-MGPS	0.751	0.574	0.770	0.498	0.665	0.601
BCPNN	0.670	0.445	0.867	0.428	0.570	0.573
LP-BCPNN	0.671	0.449	0.911	0.428	0.574	0.573

Evaluation metrics of fixed levels of sensitivities and specificities values can be found in Table S1 of Additional file 1. The bold in the table is maximum values of that evaluation metrics on different methods

ISSN: 1472-6947