Table 1 Summary of clinical trial termination rates within levels of each structured variable
From: Latent Dirichlet Allocation in predicting clinical trial terminations
Characteristic | Level | total_n | Completed | Terminated |
|---|---|---|---|---|
Primary Purpose | Missing | 29484 | 0.94 | 0.06 |
Primary Purpose | Basic Science | 4915 | 0.94 | 0.06 |
Primary Purpose | Device Feasibility | 52 | 0.83 | 0.17 |
Primary Purpose | Diagnostic | 3858 | 0.87 | 0.13 |
Primary Purpose | Educational/Counseling/Training | 118 | 0.89 | 0.11 |
Primary Purpose | Health Services Research | 1971 | 0.96 | 0.04 |
Primary Purpose | Other | 795 | 0.91 | 0.09 |
Primary Purpose | Prevention | 11939 | 0.93 | 0.07 |
Primary Purpose | Screening | 723 | 0.93 | 0.07 |
Primary Purpose | Supportive Care | 3491 | 0.91 | 0.09 |
Primary Purpose | Treatment | 76625 | 0.88 | 0.12 |
Intervention Type | Behavioral | 10147 | 0.97 | 0.03 |
Intervention Type | Biological | 7770 | 0.90 | 0.10 |
Intervention Type | Combination Product | 8 | 1.00 | 0.00 |
Intervention Type | Device | 10957 | 0.88 | 0.12 |
Intervention Type | Diagnostic Test | 73 | 0.96 | 0.04 |
Intervention Type | Dietary Supplement | 3811 | 0.95 | 0.05 |
Intervention Type | Drug | 65364 | 0.88 | 0.12 |
Intervention Type | Genetic | 500 | 0.90 | 0.10 |
Intervention Type | Other1 | 11302 | 0.93 | 0.07 |
Intervention Type | Procedure | 8908 | 0.89 | 0.11 |
Intervention Type | Radiation | 751 | 0.78 | 0.22 |
Study Phase | Early Phase 1 | 915 | 0.88 | 0.12 |
Study Phase | Missing1 | 54082 | 0.93 | 0.07 |
Study Phase | Phase 1 | 17396 | 0.91 | 0.09 |
Study Phase | Phase 1/Phase 2 | 4432 | 0.84 | 0.16 |
Study Phase | Phase 2 | 22544 | 0.85 | 0.15 |
Study Phase | Phase 2/Phase 3 | 2423 | 0.87 | 0.13 |
Study Phase | Phase 3 | 17992 | 0.89 | 0.11 |
Study Phase | Phase 4 | 14187 | 0.90 | 0.10 |
Intervention Model | Missing2 | 27542 | 0.93 | 0.07 |
Intervention Model | Crossover Assignment | 11597 | 0.95 | 0.05 |
Intervention Model | Factorial Assignment | 1836 | 0.94 | 0.06 |
Intervention Model | Parallel Assignment | 61036 | 0.90 | 0.10 |
Intervention Model | Sequential Assignment | 49 | 0.90 | 0.10 |
Intervention Model | Single Group Assignment | 31911 | 0.86 | 0.14 |
Allocation | Missing3 | 45626 | 0.90 | 0.10 |
Allocation | Non-Randomized | 14325 | 0.88 | 0.12 |
Allocation | Random Sample | 40 | 0.93 | 0.07 |
Allocation | Randomized | 73980 | 0.91 | 0.09 |
Enrollment Group | > 1000 | 7151 | 0.96 | 0.04 |
Enrollment Group | 0-100 | 80755 | 0.87 | 0.13 |
Enrollment Group | 101-1000 | 42683 | 0.94 | 0.06 |
Enrollment Group | Missing4 | 3382 | 0.95 | 0.05 |