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Table 3 Associations of DIABETIMSS program and glycemic control indicator by clinic and pooled over all clinics

From: Application of machine learning methodology to assess the performance of DIABETIMSS program for patients with type 2 diabetes in family medicine clinics in Mexico

ClinicDIABETIMSSnUnadjusted logistic regressionAdjusted logistic regressionTMLE
   HbA1c < 7% (95% CI)HbA1c < 7% (95% CI)HbA1c < 7% (95% CI)
ANo47780.3599 (0.3517, 0.3680)0.3692 (0.3574, 0.3810)0.3694 (0.3577, 0.3812)
Yes5730.4122 (0.3864, 0.4381)0.3907 (0.3564, 0.4249)0.3997 (0.3665, 0.4329)
RD 0.0524 (0.0252, 0.0795)0.0215 (−0.0141, 0.0570)0.0302 (−0.0131, 0.0736)
BNo63350.4027 (0.3950, 0.4103)0.4028 (0.3918, 0.4138)0.4034 (0.3926, 0.4143)
Yes23240.3901 (0.3777, 0.4025)0.4530 (0.4368, 0.4693)0.4598 (0.4444, 0.4752)
RD -0.0125 (−0.0271, 0.0020)0.0502 (0.0312, 0.0693)0.0564 (0.0334, 0.0794)
CNo115350.3419 (0.3369, 0.3470)0.3285 (0.3222, 0.3349)0.3291 (0.3228, 0.3354)
Yes32690.3713 (0.3612, 0.3814)0.3694 (0.3554, 0.3833)0.3815 (0.3673, 0.3957)
RD 0.0293 (0.0181, 0.0406)0.0408 (0.0255, 0.0561)0.0524 (0.0310, 0.0737)
DNo35000.3067 (0.2982, 0.3151)0.2911 (0.2801, 0.3022)0.2917 (0.2809, 0.3026)
Yes22080.3446 (0.3330, 0.3563)0.3382 (0.3252, 0.3513)0.3385 (0.3257, 0.3513)
RD 0.0380 (0.0236, 0.0523)0.0471 (0.0307, 0.0635)0.0468 (0.0272, 0.0663)
ENo10500.1570 (0.1483, 0.1657)0.1624 (0.1503, 0.1746)0.1623 (0.1501, 0.1744)
Yes2290.1717 (0.1514, 0.1919)0.1860 (0.1551, 0.2169)0.1781 (0.1493, 0.2069)
RD 0.0147 (−0.0073, 0.0367)0.0236 (−0.0095, 0.0567)0.0158 (−0.0239, 0.0555)
FNo11600.2049 (0.1944, 0.2154)0.2370 (0.2219, 0.2520)0.2376 (0.2226, 0.2527)
Yes3370.2590 (0.2352, 0.2828)0.3073 (0.2753, 0.3393)0.3169 (0.2844, 0.3494)
RD 0.0542 (0.0281, 0.0802)0.0703 (0.0351, 0.1056)0.0793 (0.0360, 0.1226)
AllNo283250.3278 (0.3247, 0.3309)0.3225 (0.3184, 0.3266)0.3227 (0.3185, 0.3268)
Yes89400.3548 (0.3489, 0.3608)0.3692 (0.3617, 0.3768)0.3716 (0.3639, 0.3794)
RD 0.027 (0.0204, 0.0337)0.0467 (0.0383, 0.0552)0.0490 (0.0377, 0.0602)
  1. The estimates displayed in this table represent the proportion of subjects with HbA1c < 7% within each group (DIABETIMSS Yes/No) as well as the difference of these proportions in the two groups. We show three estimators as discussed in text: unadjusted, adjusted within a logistic regression and finally using targeted maximum likelihood estimation (TMLE)