ThalPred: a web-based prediction tool for discriminating thalassemia trait and iron deficiency anemia

Laengsri, V.; Shoombuatong, W.; Adirojananon, W.; Nantasenamat, C.; Prachayasittikul, V.; Nuchnoi, P.

doi:10.1186/s12911-019-0929-2

BMC Medical Informatics and Decision Making

Table 6 The prediction results derived from DT, RF and SVM models in differentiation of iron deficiency anemia (IDA) from thalassemia trait (TT)

From: ThalPred: a web-based prediction tool for discriminating thalassemia trait and iron deficiency anemia

No.	RBC	Hb	Hct	MCV	MCH	MCHC	RDW	Diagnosis	Prediction
No.	RBC	Hb	Hct	MCV	MCH	MCHC	RDW	Diagnosis	k-NN	DT	RF	ANN	SVM
1	5.35	10.6	33.0	61.7	19.8	32.1	13.7	TT	TT	TT	TT	TT	TT
2	5.40	10.9	34.1	63.2	20.2	32.0	14.5	TT	TT	TT	TT	TT	TT
3	5.40	10.3	33.0	61.1	19.1	31.2	14.2	TT	TT	TT	TT	TT	TT
4	6.01	12.3	38.3	63.7	20.5	32.1	13.2	TT	TT	TT	TT	TT	TT
5	5.55	11.0	33.4	60.2	19.8	32.9	13.2	TT	TT	TT	TT	TT	TT
6	6.04	12.9	39.6	65.6	21.4	32.6	13.5	TT	TT	TT	TT	TT	TT
7	5.90	13.1	40.0	67.8	22.2	32.8	12.7	TT	TT	TT	TT	TT	TT
8	5.95	12.6	39.0	65.6	21.2	32.3	13.4	TT	TT	TT	TT	TT	TT
9	6.11	12.7	39.5	64.7	20.8	32.2	13.7	TT	TT	TT	TT	TT	TT
10	5.45	11.8	36.6	67.1	21.7	32.3	14.0	TT	TT	TT	TT	TT	TT
11	5.40	11.0	34.0	63.0	20.4	32.4	12.8	TT	TT	TT	TT	TT	TT
12	5.40	11.0	34.0	63.0	20.4	32.4	14.0	TT	TT	TT	TT	TT	TT
13	6.20	12.4	37.2	60.0	20.0	33.3	12.6	TT	TT	TT	TT	TT	TT
14	5.40	10.7	33.0	61.1	19.8	32.4	13.6	TT	TT	TT	TT	TT	TT
15	6.11	12.3	38.0	62.2	20.1	32.4	12.6	TT	TT	TT	TT	TT	TT
16	3.40	7.7	24.1	70.9	22.7	32.0	20.1	IDA	IDA	IDA	IDA	IDA	IDA
17	4.66	11.3	34.4	73.8	24.3	32.9	21.0	IDA	TT	TT	TT	IDA	TT
18	4.54	10.6	32.8	72.3	23.4	32.3	21.0	IDA	IDA	IDA	IDA	IDA	IDA
19	3.50	7.9	25.2	72.0	22.6	31.4	21.2	IDA	IDA	IDA	IDA	IDA	IDA
20	4.15	9.9	29.0	69.9	23.9	34.1	20.2	IDA	TT	IDA	IDA	IDA	IDA
21	3.90	8.9	28.0	71.8	22.8	31.8	20.2	IDA	IDA	IDA	IDA	IDA	IDA
22	4.17	9.9	29.0	69.5	23.7	34.1	21.1	IDA	IDA	IDA	IDA	IDA	IDA
23	3.85	8.5	27.5	71.4	22.1	30.9	21.3	IDA	IDA	IDA	IDA	IDA	IDA
24	4.24	9.8	30.5	71.9	23.1	32.1	20.2	IDA	IDA	IDA	IDA	IDA	IDA
25	4.83	11.1	34.0	70.4	23.0	32.7	19.0	IDA	TT	TT	TT	TT	TT
26	4.64	10.6	33.0	71.1	22.8	32.1	20.5	IDA	IDA	IDA	IDA	IDA	IDA
27	4.01	9.5	29.0	72.3	23.7	32.8	20.4	IDA	IDA	IDA	IDA	IDA	IDA
28	4.80	11.0	34.0	70.8	22.9	32.4	21.1	IDA	TT	TT	TT	IDA	IDA
29	3.65	8.4	26.0	71.2	23.0	32.3	20.4	IDA	IDA	IDA	IDA	IDA	IDA
30	4.00	9.2	28.0	70.0	23.0	32.9	20.1	IDA	IDA	IDA	IDA	IDA	IDA
31	4.45	10.2	31.4	70.6	22.9	32.5	19.8	IDA	IDA	IDA	IDA	IDA	IDA
32	4.44	10.3	32.0	72.1	23.2	32.2	21.3	IDA	IDA	IDA	IDA	IDA	IDA
33	4.56	10.4	32.0	70.2	22.8	32.5	19.4	IDA	IDA	IDA	IDA	IDA	IDA
34	4.84	11.0	34.0	70.3	22.7	32.4	20.7	IDA	TT	TT	TT	IDA	IDA
36	3.83	8.7	27.0	70.5	22.72	32.22	20.0	IDA	IDA	IDA	IDA	IDA	IDA
37	3.6	8.7	25.0	69.44	24.17	34.8	19.3	IDA	IDA	IDA	IDA	IDA	IDA
38	3.52	8.0	25.0	71.02	22.73	32	21.1	IDA	IDA	IDA	IDA	IDA	IDA
39	3.98	9.0	27.8	69.85	22.61	32.37	20.7	IDA	IDA	IDA	IDA	IDA	IDA
40	4.02	9.0	28.5	70.9	22.39	31.58	21.1	IDA	IDA	IDA	IDA	IDA	IDA
41	4.43	10.1	31.4	70.88	22.8	32.17	19.8	IDA	IDA	IDA	IDA	IDA	IDA
42	4.24	9.6	30.0	70.75	22.64	32.0	21.0	TT	TT	TT	TT	TT	TT
43	5.94	12.6	39.0	65.7	21.2	32.3	13.0	TT	IDA	TT	TT	IDA	TT
44	5.80	11.7	36.3	62.6	20.2	32.2	13.1	TT	IDA	TT	TT	IDA	TT
45	5.45	11.4	35.0	64.2	20.9	32.6	13.0	TT	IDA	TT	TT	IDA	TT
46	5.40	11.0	33.7	62.4	20.4	32.6	12.5	TT	IDA	TT	TT	IDA	TT
47	6.11	12.6	38.5	63.0	20.6	32.7	14.3	TT	IDA	TT	TT	IDA	TT
48	5.80	12.2	36.4	62.8	21.0	33.5	14.0	TT	IDA	TT	TT	IDA	TT
49	5.44	10.8	34.0	62.5	19.9	31.8	12.7	TT	IDA	TT	TT	IDA	TT
50	5.40	10.8	33.0	61.1	20.0	32.7	13.6	TT	TT	TT	TT	TT	TT
51	6.05	12.3	38.0	62.8	20.3	32.4	14.0	TT	TT	TT	TT	TT	TT

ANN Artificial neural network; DT Decision tree; Hb Hemoglobin; Hct Hematocrit; IDA Iron deficiency anemia; k-NN k-nearest neighbor; MCH mean corpuscular hemoglobin; MCHC mean corpuscular hemoglobin concentration; MCV mean corpuscular volume; RBC red blood cell count; RDW red blood cell distribution width; RF Random forest; SVM Support vector machine; TT Thalassemia trait. Parameters of k-NN (k), RF (ntree, mtry), ANN (size, decay) and SVM (cost, γ) were optimized by a 5-fold CV procedure. Values of k, ntree, mtry, size, decay, cost and γ are 5, 200, 2, 4, 0.5, 8 and 0.5

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