Table 1 Input parameters of the DES model

Patient arrivals

Patient arrival rates per weekday, per tumor site (8 independent generators)

Poisson

–

Care plan

Proportion of patients in each of the 62 possible care trajectories depending on tumor site (generators)

Empirical

Tumor site

Urgency level

Proportion of acute, subacute, and regular per care plan

Empirical

Care plan

Steps needed

Proportion of patients with CT, MRI, PET-CT, warping, image registration, contouring, and treatment planning type, per care plan, per urgency level

Empirical

Care plan Urgency level

CT/MRI/PET-CT processing times

CT = 25 min. MRI = 45 min, and PET-CT = 45 min, regardless of other parameters.

–

–

Image Post-processing times

Mean and standard deviation of the duration for processing warping and image registration.

Lognormal

–

Contouring time

60 min for tumor contouring, and 60 min for peer-review review.

–

–

Treatment planning times

Processing times of P2, P3, and P4, depending on the care plan.

–

Care plan

Scheduling of first fraction

Proportion of patients for each possible duration of the time-to-treatment (0 … 21 days) per urgency level, per weekday

Empirical

Weekday Urgency level

Planned delay

Proportion of patients with a planned delay before pre-treatment, and the length of the delay (1 … 8 weeks), per care plan

Empirical

Care plan

Machine availability

Time of the day each CT, MRI, and PET-CT is available to be operated

–

–

Doctors’ agenda

Start time and end time for each day of the simulation period, and parts of the day the doctor is unavailable due to other scheduled activities (meetings, research, etc.)

–

–

RTTs’ agenda

Start time and end time for each day of the simulation period

–

–

Public holidays and days-off

Days of the simulation period in which the clinic is not operating, and days each RTT and doctor is unavailable (days-off)

–

–