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Table 4 Outcomes, instruments used, and effects of decisions aids evaluated in the included one-group pretest-posttest design study

From: Effectiveness of decision aids for female BRCA1 and BRCA2 mutation carriers: a systematic review

Outcomes

Instruments used for assessment

Pretest-posttest study using the instrument

Score (S.D.)

p-value

Main results

Decision related outcomes

 Decisional conflict

Decisional Conflict Scalea

Metcalfe 2007 [27]

Pre-test 36.2 (16.4), Post-test 23.0 (15.2)

0.001

Significantly less decisional conflict after using the DA.

 Strenght of treatment preference

15-point scale

Metcalfe 2007 [27]

RR-M:

 

Significantly fewer women in the DA group were uncertain about RR-M and RR-O.

Pre-test No 14, Yes 3, Unsure 3

 

Post-test No 10, Yes 4, Unsure 6

0.009

RR-O:

 

Pre-test No 5, Yes 12, Unsure 3

 

Post-test No 2, Yes 15, Unsure 3

0.003

Tamoxifen:

 

Pre-test No 10, Yes 1, Unsure 9

 

Post-test No 11, Yes 5, Unsure 4

0.12

Information related outcomes

 Risk perception

BC risk, mutation carriersb

Metcalfe 2007 [27]

Pre-test 65.1 (16.1), Post-test 73.6 (13.4)

0.05

Significantly better risk perception after using the DA.

BC, risk after RR-M, mutation carriersb

Metcalfe 2007 [27]

Pre-test 71.8 (22.0), Post-test 84.2 (18.2)

0.005

Significantly better risk perception after using the DA.

BC, risk after RR-O, mutation carriersb

Metcalfe 2007 [27]

Pre-test 43.2 (20.0), Post-test 65.0 (13.3)

0.001

Significantly better risk perception after using the DA.

BC, risk with Tamoxifen, mutation carriersb

Metcalfe 2007 [27]

Pre-test 50.0 (19.0), Post-test 56.6 (10.0)

0.17

No significant difference.

BC, risk with mammography, mutation carriersb

Metcalfe 2007 [27]

Pre-test 21.5 (28.0), Post-test 13.5 (22.8)

0.11

No significant difference.

Health outcomes

 Distress

Impact of Event Scalea

Metcalfe 2007 [27]

Pre-test 22.7 (13.7), Post-test 19.9 (14.5)

0.24

No significant difference.

  1. DA decision aid, BC breast cancer, RR-M risk-reducing mastectomy, RR-O risk-reducing oophorectomy
  2. ainstrument was validated in a study
  3. brisk estimates from 0 to 100%