Table 5 Univariate and multivariate logistic regression analyses of predictive variables for having psychotropic interactions in 2000, and 2016, among patients in three nursing homes with 386 and 416 patients the respective years
Predictive variables | 2000 | 2016 | ||||||
|---|---|---|---|---|---|---|---|---|
n = 386 | n = 416 | |||||||
Unadjusted model | Adjusted model | Unadjusted model | Adjusted model | |||||
OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
Gender | 1.60 (0.59–4.31) | 0.358 | 1.26 (0.72–2.18) | 0.425 | ||||
Age | 0.99 (0.94–1.05) | 0.741 | 0.99 (0.96–1.02) | 0.457 | ||||
Number of psychotropic drugs | 4.28 (1.25–14.64) | 0.021 | 6.06 (1.61–22.81) | 0.008 | 2.95 (1.97–4.42) | < 0.001 | 2.58 (1.43–4.63) | 0.002 |
Prescribed antidepressants | 4.52 (1.80–11.34) | 0.001 | 3.18 (1.12–9.04) | 0.030 | 45.98 (20.80–101.67) | < 0.001 | 29.00 (12.23–68.77) | < 0.001 |
Prescribed antipsychotics | 1.62 (0.68–3.86) | 0.274 | 0.54 (0.31–0.92) | 0.023 | 0.61 (0.24–1.51) | 0.282 | ||
Prescribed anxiolytics-hypnotics | 0.09 (0.02–0.42) | 0.002 | 0.07 (0.02–0.35) | 0.001 | 0.57 (0.24–1.35) | 0.200 | 0.51 (0.15–1.78) | 0.293 |
Prescribed antiepileptics | 1.97 (0.51–7.67) | 0.326 | 0.95 (0.49–1.84) | 0.879 | ||||