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Fig. 5 | BMC Medical Informatics and Decision Making

Fig. 5

From: Gene fingerprint model for literature based detection of the associations among complex diseases: a case study of COPD

Fig. 5

Enrichment analysis with DAVID 6.8 of the associated genes for the 4 novel diseases and COPD. Two enriched KEGG pathways shared by the four diseases. a Venn graph to show the number of overlapping enriched KEGG pathways among the 4 diseases. LI: Lung injury; PS: Pulmonary Sarcoidosis; COPD: Chronic Obstructive Pulmonary Disease; ALI: Acute Lung Injury. Two KEGG pathways are shared by the four diseases. b HIF-1 Signaling pathway. c Pathways in cancer. Different colors of the box represent the genes in the pathway that are shared by different diseases. Blue: ALI & COPD; red: ALI & LI & COPD & PS; yellow: ALI & COPD & PS; black: LI & COPD; purple: ALI & LI & COPD; orange: COPD & PS; gray: COPD unique except for LPAR1 which is LI unique. RELA belongs to LI & COPD, ERBB2 belongs to ALI & COPD, MMP2 and MMP9 belong to ALI & LI & COPD, LPAR1 is LI unique. Since they correspond to the same KEGG symbol with other genes, the colors are represented by the first gene in each group

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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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