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Table 23 Findings of the replicated studies compared to our results

From: Replicating medication trend studies using ad hoc information extraction in a clinical data warehouse

 

Finding

Rep.

 

Main findings

 

1

The absolute number of patients initiating OAC has increased among patients aged <65, 65 to 74, and ≥85 years

yes

2

The utilization of VKAs has decreased since the introduction of NOACs

yes

3

From 2014 [to 2015] the utilization of dabigatran has decreased, especially among patients aged ≥85 years

yes

4

Apixaban has increased significantly and was the most used NOAC drug among patients aged ≥85 years

(yes)

 

Other results

 

5

For patients aged 75 to 84 years, number of patients initiating OAC treatment stayed approximately the same

no

6

The utilization of dabigatran increased within a couple of months since its introduction to the market

yes

7

A fairly constant level of dabigatran utilization was seen from December 2011 of approximately 40%

no

8

Rivaroxaban has steadily increased usage and at study end 29%

yes

  1. Study: Non-vitamin K antagonist oral anticoagulation usage according to age among patients with atrial fibrillation: Temporal trends 2011–2015 in Denmark