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Fig. 1 | BMC Medical Informatics and Decision Making

Fig. 1

From: Trio-R: a script for assessing maternity and paternity in trio studies performed on Agilent chromosomal microarrays

Fig. 1

Performance of the script in a test involving 10 putative trios. a The distributions for the proportions of discordant loci for true-pairs (“Parents”; median = 0.0031, range = 0.0013–0.0072) and false-pairs (“Non-parents”; median = 0.092, range = 0.077 to 0.19) were clearly distinct. b A similar result was obtained for the numbers of discordant loci (for true-pairs/“Parents”; median = 39.5, range = 18–62; for false pairs/“Non-parents”; median = 1129, range = 920–2165). c By contrast, the numbers of concordant loci overlapped, suggesting that these do not reliably separate true-pairs from false-pairs. Overall, we considered the proportion of discordant loci to be the most reliable measure (see Implementation section)

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